Immunogenicity 11493

summary
Sample ID
3309
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SMG1
Transcript ID
uc002dfm.3
HLA INFO
A*01:01
TCR INFO

No TCR info found!

T cell Tumor cell A*01:01
sequence
Full length protein sequence (3661 aa)
MSRRA
1
PGSRL
6
SSGGG
11
GGGTK
16
YPRSW
21
NDWQP
26
RTDSA
31
SADPD
36
NLKYS
41
SSRDR
46
GGSSS
51
YGLQP
56
SNSAV
61
VSRQR
66
HDDTR
71
VHADI
76
QNDEK
81
GGYSV
86
NGGSG
91
ENTYG
96
RKSLG
101
QELRV
106
NNVTS
111
PEFTS
116
VQHGS
121
RALAT
126
KDMRK
131
SQERS
136
MSYSD
141
ESRLS
146
NLLRR
151
ITRED
156
DRDRR
161
LATVK
166
QLKEF
171
IQQPE
176
NKLVL
181
VKQLD
186
NILAA
191
VHDVL
196
NESSK
201
LLQEL
206
RQEGA
211
CCLGL
216
LCASL
221
SYEAE
226
KIFKW
231
IFSKF
236
SSSAK
241
DEVKL
246
LYLCA
251
TYKAL
256
ETVGE
261
KKAFS
266
SVMQL
271
VMTSL
276
QSILE
281
NVDTP
286
ELLCK
291
CVKCI
296
LLVAR
301
CYPHI
306
FSTNF
311
RDTVD
316
ILVGW
321
HIDHT
326
QKPSL
331
TQQVS
336
GWLQS
341
LEPFW
346
VADLA
351
FSTTL
356
LGQFL
361
EDMEA
366
YAEDL
371
SHVAS
376
GESVD
381
EDVPP
386
PSVSL
391
PKLAA
396
LLRVF
401
STVVR
406
SIGER
411
FSPIR
416
GPPIT
421
EAYVT
426
DVLYR
431
VMRCV
436
TAANQ
441
VFFSE
446
AVLTA
451
ANECV
456
GVLLG
461
SLDPS
466
MTIHC
471
DMVIT
476
YGLDQ
481
LENCQ
486
TCGTD
491
YIISV
496
LNLLT
501
LIVEQ
506
INTKL
511
PSSFV
516
EKLFI
521
PSSKL
526
LFLRY
531
HKEKE
536
VVAVA
541
HAVYQ
546
AVLSL
551
KNIPV
556
LETAY
561
KLILG
566
EMTCA
571
LNNLL
576
HSLQL
581
PEACS
586
EIKHE
591
AFKNH
596
VFNVD
601
NAKFV
606
VIFDL
611
SALTT
616
IGNAK
621
NSLIG
626
MWALS
631
PTVFA
636
LLSKN
641
LMIVH
646
SDLAV
651
HFPAI
656
QYAVL
661
YTLYS
666
HCTRH
671
DHFIS
676
SSLSS
681
SSPSL
686
FDGAV
691
ISTVT
696
TATKK
701
HFSII
706
LNLLG
711
ILLKK
716
DNLNQ
721
DTRKL
726
LMTWA
731
LEAAV
736
LMKKS
741
ETYAP
746
LFSLP
751
SFHKF
756
CKGLL
761
ANTLV
766
EDVNI
771
CLQAC
776
SSLHA
781
LSSSL
786
PDDLL
791
QRCVD
796
VCRVQ
801
LVHSG
806
TRIRQ
811
AFGKL
816
LKSIP
821
LDVVL
826
SNNNH
831
TEIQE
836
ISLAL
841
RSHMS
846
KAPSN
851
TFHPQ
856
DFSDV
861
ISFIL
866
YGNSH
871
RTGKD
876
NWLER
881
LFYSC
886
QRLDK
891
RDQST
896
IPRNL
901
LKTDA
906
VLWQW
911
AIWEA
916
AQFTV
921
LSKLR
926
TPLGR
931
AQDTF
936
QTIEG
941
IIRSL
946
AAHTL
951
NPDQD
956
VSQWT
961
TADND
966
EGHGN
971
NQLRL
976
VLLLQ
981
YLENL
986
EKLMY
991
NAYEG
996
CANAL
1001
TSPPK
1006
VIRTF
1011
FYTNR
1016
QTCQD
1021
WLTRI
1026
RLSIM
1031
RVGLL
1036
AGQPA
1041
VTVRH
1046
GFDLL
1051
TEMKT
1056
TSLSQ
1061
GNELE
1066
VTIMM
1071
VVEAL
1076
CELHC
1081
PEAIQ
1086
GIAVW
1091
SSSIV
1096
GKNLL
1101
WINSV
1106
AQQAE
1111
GRFEK
1116
ASVEY
1121
QEHLC
1126
AMTGV
1131
DCCIS
1136
SFDKS
1141
VLTLA
1146
NAGRN
1151
SASPK
1156
HSLNG
1161
ESRKT
1166
VLSKP
1171
TDSSP
1176
EVINY
1181
LGNKA
1186
CECYI
1191
SIADW
1196
AAVQE
1201
WQNAI
1206
HDLKK
1211
STSST
1216
SLNLK
1221
ADFNY
1226
IKSLS
1231
SFESG
1236
KFVEC
1241
TEQLE
1246
LLPGE
1251
NINLL
1256
AGGSK
1261
EKIDM
1266
KKLLP
1271
NMLSP
1276
DPREL
1281
QKSIE
1286
VQLLR
1291
SSVCL
1296
ATALN
1301
PIEQD
1306
QKWQS
1311
ITENV
1316
VKYLK
1321
QTSRI
1326
AIGPL
1331
RLSTL
1336
TVSQS
1341
LPVLS
1346
TLQLY
1351
CSSAL
1356
ENTVS
1361
NRLST
1366
EDCLI
1371
PLFSE
1376
ALRSC
1381
KQHDV
1386
RPWMQ
1391
ALRYT
1396
MYQNQ
1401
LLEKI
1406
KEQTV
1411
PIRSH
1416
LMELG
1421
LTAAK
1426
FARKR
1431
GNVSL
1436
ATRLL
1441
AQCSE
1446
VQLGK
1451
TTTAQ
1456
DLVQH
1461
FKKLS
1466
TQGQV
1471
DEKWG
1476
PELDI
1481
EKTKL
1486
LYTAG
1491
QSTHA
1496
MEMLS
1501
SCAIS
1506
FCKSV
1511
KAEYA
1516
VAKSI
1521
LTLAK
1526
WIQAE
1531
WKEIS
1536
GQLKQ
1541
VYRAQ
1546
HQQNF
1551
TGLST
1556
LSKNI
1561
LTLIE
1566
LPSVN
1571
TMEEE
1576
YPRIE
1581
SESTV
1586
HIGVG
1591
EPDFI
1596
LGQLY
1601
HLSSV
1606
QAPEV
1611
AKSWA
1616
ALASW
1621
AYRWG
1626
RKVVD
1631
NASQG
1636
EGVRL
1641
LPREK
1646
SEVQN
1651
LLPDT
1656
ITEEE
1661
KERIY
1666
GILGQ
1671
AVCRP
1676
AGIQD
1681
EDITL
1686
QITES
1691
EDNEE
1696
DDMVD
1701
VIWRQ
1706
LISSC
1711
PWLSE
1716
LDESA
1721
TEGVI
1726
KVWRK
1731
VVDRI
1736
FSLYK
1741
LSCSA
1746
YFTFL
1751
KLNAG
1756
QIPLD
1761
EDDPR
1766
LHLSH
1771
RVEQS
1776
TDDMI
1781
VMATL
1786
RLLRL
1791
LVKHA
1796
GELRQ
1801
YLEHG
1806
LETTP
1811
TAPWR
1816
GIIPQ
1821
LFSRL
1826
NHPEV
1831
YVRQS
1836
ICNLL
1841
CRVAQ
1846
DSPHL
1851
ILYPA
1856
IVGTI
1861
SLSSE
1866
SQASG
1871
NKFST
1876
AIPTL
1881
LGNIQ
1886
GEELL
1891
VSECE
1896
GGSPP
1901
ASQDS
1906
NKDEP
1911
KSGLN
1916
EDQAM
1921
MQDCY
1926
SKIVD
1931
KLSSA
1936
NPTMV
1941
LQVQM
1946
LVAEL
1951
RRVTV
1956
LWDEL
1961
WLGVL
1966
LQQHM
1971
YVLRR
1976
IQQLE
1981
DEVKR
1986
VQNNN
1991
TLRKE
1996
EKIAI
2001
MREKH
2006
TALMK
2011
PIVFA
2016
LEHVR
2021
SITAA
2026
PAETP
2031
HEKWF
2036
QDNYG
2041
DAIEN
2046
ALEKL
2051
KTPLN
2056
PAKPG
2061
SSWIP
2066
FKEIM
2071
LSLQQ
2076
RAQKR
2081
ASYIL
2086
RLEEI
2091
SPWLA
2096
AMTNT
2101
EIALP
2106
GEVSA
2111
RDTVT
2116
IHSVG
2121
GTITI
2126
LPTKT
2131
KPKKL
2136
LFLGS
2141
DGKSY
2146
PYLFK
2151
GLEDL
2156
HLDER
2161
IMQFL
2166
SIVNT
2171
MFATI
2176
NRQET
2181
PRFHA
2186
RHYSV
2191
TPLGT
2196
RSGLI
2201
QWVDG
2206
ATPLF
2211
GLYKR
2216
WQQRE
2221
AALQA
2226
QKAQD
2231
SYQTP
2236
QNPGI
2241
VPRPS
2246
ELYYS
2251
KIGPA
2256
LKTVG
2261
LSLDV
2266
SRRDW
2271
PLHVM
2276
KAVLE
2281
ELMEA
2286
TPPNL
2291
LAKEL
2296
WSSCT
2301
TPDEW
2306
WRVTQ
2311
SYARS
2316
TAVMS
2321
MVGYI
2326
IGLGD
2331
RHLDN
2336
VLIDM
2341
TTGEV
2346
VHIDY
2351
NVCFE
2356
KGKSL
2361
RVPEK
2366
VPFRM
2371
TQNIE
2376
TALGV
2381
TGVEG
2386
VFRLS
2391
CEQVL
2396
HIMRR
2401
GRETL
2406
LTLLE
2411
AFVYD
2416
PLVDW
2421
TAGGE
2426
AGFAG
2431
AVYGG
2436
GGQQA
2441
ESKQS
2446
KREME
2451
REITR
2456
SLFSS
2461
RVAEI
2466
KVNWF
2471
KNRDE
2476
MLVVL
2481
PKLDG
2486
SLDEY
2491
LSLQE
2496
QLTDV
2501
EKLQG
2506
KLLEE
2511
IEFLE
2516
GAEGV
2521
DHPSH
2526
TLQHR
2531
YSEHT
2536
QLQTQ
2541
QRAVQ
2546
EAIQV
2551
KLNEF
2556
EQWIT
2561
HYQAA
2566
FNNLE
2571
ATQLA
2576
SLLQE
2581
ISTQM
2586
DLGPP
2591
SYVPA
2596
TAFLQ
2601
NAGQA
2606
HLISQ
2611
CEQLE
2616
GEVGA
2621
LLQQR
2626
RSVLR
2631
GCLEQ
2636
LHHYA
2641
TVALQ
2646
YPKAI
2651
FQKHR
2656
IEQWK
2661
TWMEE
2666
LICNT
2671
TVERC
2676
QELYR
2681
KYEMQ
2686
YAPQP
2691
PPTVC
2696
QFITA
2701
TEMTL
2706
QRYAA
2711
DINSR
2716
LIRQV
2721
ERLKQ
2726
EAVTV
2731
PVCED
2736
QLKEI
2741
ERCIK
2746
VFLHE
2751
NGEEG
2756
SLSLA
2761
SVIIS
2766
ALCTL
2771
TRRNL
2776
MMEGA
2781
ASSAG
2786
EQLVD
2791
LTSRD
2796
GAWFL
2801
EELCS
2806
MSGNV
2811
TCLVQ
2816
LLKQC
2821
HLVPQ
2826
DLDIP
2831
NPMEA
2836
SETVH
2841
LANGV
2846
YTSLQ
2851
ELNSN
2856
FRQII
2861
FPEAL
2866
RCLMK
2871
GEYTL
2876
ESMLH
2881
ELDGL
2886
IEQTT
2891
DGVPL
2896
QTLVE
2901
SLQAY
2906
LRNAA
2911
MGLEE
2916
ETHAH
2921
YIDVA
2926
RLLHA
2931
QYGEL
2936
IQPRN
2941
GSVDE
2946
TPKMS
2951
AGQML
2956
LVAFD
2961
GMFAQ
2966
VETAF
2971
SLLVE
2976
KLNKM
2981
EIPIA
2986
WRKID
2991
IIREA
2996
RSTQV
3001
NFFDD
3006
DNHRQ
3011
VLEEI
3016
FFLKR
3021
LQTIK
3026
EFFRL
3031
CGTFS
3036
KTLSG
3041
SSSLE
3046
DQNTV
3051
NGPVQ
3056
IVNVK
3061
TLFRN
3066
SCFSE
3071
DQMAK
3076
PIKAF
3081
TADFV
3086
RQLLI
3091
GLPNQ
3096
ALGLT
3101
LCSFI
3106
SALGV
3111
DIIAQ
3116
VEAKD
3121
FGAES
3126
KVSVD
3131
DLCKK
3136
AVEHN
3141
IQIGK
3146
FSQLV
3151
MNRAT
3156
VLASS
3161
YDTAW
3166
KKHDL
3171
VRRLE
3176
TSISS
3181
CKTSL
3186
QRVQL
3191
HIAMF
3196
QWQHE
3201
DLLIN
3206
RPQAM
3211
SVTPP
3216
PRSAI
3221
LTSMK
3226
KKLHT
3231
LSQIE
3236
TSIAT
3241
VQEKL
3246
AALES
3251
SIEQR
3256
LKWAG
3261
GANPA
3266
LAPVL
3271
QDFEA
3276
TIAER
3281
RNLVL
3286
KESQR
3291
ASQVT
3296
FLCSN
3301
IIHFE
3306
SLRTR
3311
TAEAL
3316
NLDAA
3321
LFELI
3326
KRCQQ
3331
MCSFA
3336
SQFNS
3341
SVSEL
3346
ELRLL
3351
QRVDT
3356
GLEHP
3361
IGSSE
3366
WLLSA
3371
HKQLT
3376
QDMST
3381
QRAIQ
3386
TEKEQ
3391
QIETV
3396
CETIQ
3401
NLVDN
3406
IKTVL
3411
TGHNR
3416
QLGDV
3421
KHLLK
3426
AMAKD
3431
EEAAL
3436
ADGED
3441
VPYEN
3446
SVRQF
3451
LGEYK
3456
SWQDN
3461
IQTVL
3466
FTLVQ
3471
AMGQV
3476
RSQEH
3481
VEMLQ
3486
EITPT
3491
LKELK
3496
TQSQS
3501
IYNNL
3506
VSFAS
3511
PLVTD
3516
ATNEC
3521
SSPTS
3526
SATYQ
3531
PSFAA
3536
AVRSN
3541
TGQKT
3546
QPDVM
3551
SQNAR
3556
KLIQK
3561
NLATS
3566
ADTPP
3571
STVPG
3576
TGKSV
3581
ACSPK
3586
KAVRD
3591
PKTGK
3596
AVQER
3601
NSYAV
3606
SVWKR
3611
VKAKL
3616
EGRDV
3621
DPNRR
3626
MSVAE
3631
QVDYV
3636
IKEAT
3641
NLDNL
3646
AQLYE
3651
GWTAW
3656
V
3661
Mutation Information
DNA mutation:
c.4127C>T
Peptide Range:
1369 ~ 1378
Mut AA position:
1376 (8 in Wild Type peptide)
Alignment
Wild Type:
"STEDCLIPLF
|||||||.||
Mutant:
STEDCLILLF"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay