Immunogenicity 11496
Sample ID
3309
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TMC5
Transcript ID
uc002dgb.4
HLA INFO
A*11:01
TCR INFO
No TCR info found!
Full length protein sequence (948 aa)
MSAYY
1
RNNWS
6
EEDPD
11
YPDYS
16
GSQNR
21
TQGYL
26
KTQGY
31
PDVPG
36
PLNNP
41
DYPGT
46
RSNPY
51
SVASR
56
TRPDY
61
PGSLA
66
EPNYP
71
RSLSN
76
PDYSG
81
TRSNA
86
YSAAS
91
RTSPD
96
HPTSL
101
PEPDY
106
SEFQS
111
HPYHR
116
ASSRQ
121
PDYPG
126
SQRNP
131
DFAGS
136
SSSGN
141
YAGSR
146
THPDH
151
FGSLE
156
PDYPG
161
AQSNS
166
DHPGP
171
RANLN
176
HPGSR
181
KNLEH
186
TSFRI
191
NPYAD
196
SLGKP
201
DYPGA
206
DIQPN
211
SPPFF
216
GEPDY
221
PSAED
226
NQNLP
231
STWRE
236
PDYSD
241
AENGH
246
DYGSS
251
ETPKM
256
TRGVL
261
SRTSS
266
IQPSF
271
RHRSD
276
DPVGS
281
LWGEN
286
DYPEG
291
IEMAS
296
MEMAN
301
SYGHS
306
LPGAP
311
GSGYV
316
NPAYV
321
GESGP
326
VHAYG
331
NPPLS
336
ECDWH
341
KSPQG
346
QKLIA
351
SLIPM
356
TSRDR
361
IKAIR
366
NQPRT
371
MEEKR
376
NLRKI
381
VDKEK
386
SKQTH
391
RILQL
396
NCCIQ
401
CLNSI
406
SRAYR
411
RSKNS
416
LSEIL
421
NSISL
426
WQKTL
431
KIIGG
436
KFGTS
441
VLSYF
446
NFLRW
451
LLKFN
456
IFSFI
461
LNFSF
466
IIIPQ
471
FTVAK
476
KNTLQ
481
FTGLE
486
FFTGV
491
GYFRD
496
TVMYY
501
GFYTN
506
STIQH
511
GNSGA
516
SYNMQ
521
LAYIF
526
TIGAC
531
LTTCF
536
FSLLF
541
SMAKY
546
FRNNF
551
INPHI
556
YSGGI
561
TKLIF
566
CWDFT
571
VTHEK
576
AVKLK
581
QKNLS
586
TEIRE
591
NLSEL
596
RQENS
601
KLTFN
606
QLLTR
611
FSAYM
616
VAWVV
621
STGVA
626
IACCA
631
AVYYL
636
AEYNL
641
EFLKT
646
HSNPG
651
AVLLL
656
PFVVS
661
CINLA
666
VPCIY
671
SMFRL
676
VERYE
681
MPRHE
686
VYVLL
691
IRNIF
696
LKISI
701
IGILC
706
YYWLN
711
TVALS
716
GEECW
721
ETLIG
726
QDIYR
731
LLLMD
736
FVFSL
741
VNSFL
746
GEFLR
751
RIIGM
756
QLITS
761
LGLQE
766
FDIAR
771
NVLEL
776
IYAQT
781
LVWIG
786
IFFCP
791
LLPFI
796
QMIML
801
FIMFY
806
SKNIS
811
LMMNF
816
QPPSK
821
AWRAS
826
QMMTF
831
FIFLL
836
FFPSF
841
TGVLC
846
TLAIT
851
IWRII
856
TYLYW
861
QITEG
866
RKIMI
871
RLLHE
876
QIINE
881
GKDKM
886
FLIEK
891
LIKLQ
896
DMEKK
901
ANPSS
906
LVLER
911
REVEQ
916
QGFLH
921
LGEHD
926
GSLDL
931
RSRRS
936
VQEGN
941
PRA
946
Mutation Information
DNA mutation:
c.167C>T
Peptide Range:
51 ~ 60
Mut AA position:
56 (6 in Wild Type peptide)
Alignment
Wild Type:
"RSNPYSVASR
|||||.||||
Mutant:
RSNPYFVASR"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) TMC5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
COS7
Assay
IFNg ELISPOT assay