Immunogenicity 11500
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CDH5
Transcript ID
uc002eom.4
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (784 aa)
MQRLM
1
MLLAT
6
SGACL
11
GLLAV
16
AAVAA
21
AGANP
26
AQRDT
31
HSLLP
36
THRRQ
41
KRDWI
46
WNQMH
51
IDEEK
56
NTSLP
61
HHVGK
66
IKSSV
71
SRKNA
76
KYLLK
81
GEYVG
86
KVFRV
91
DAETG
96
DVFAI
101
ERLDR
106
ENISE
111
YHLTA
116
VIVDK
121
DTGEN
126
LETPS
131
SFTIK
136
VHDVN
141
DNWPV
146
FTHRL
151
FNASV
156
PESSA
161
VGTSV
166
ISVTA
171
VDADD
176
PTVGD
181
HASVM
186
YQILK
191
GKEYF
196
AIDNS
201
GRIIT
206
ITKSL
211
DREKQ
216
ARYEI
221
VVEAR
226
DAQGL
231
RGDSG
236
TATVL
241
VTLQD
246
INDNF
251
PFFTQ
256
TKYTF
261
VVPED
266
TRVGT
271
SVGSL
276
FVEDP
281
DEPQN
286
RMTKY
291
SILRG
296
DYQDA
301
FTIET
306
NPAHN
311
EGIIK
316
PMKPL
321
DYEYI
326
QQYSF
331
IVEAT
336
DPTID
341
LRYMS
346
PPAGN
351
RAQVI
356
INITD
361
VDEPP
366
IFQQP
371
FYHFQ
376
LKENQ
381
KKPLI
386
GTVLA
391
MDPDA
396
ARHSI
401
GYSIR
406
RTSDK
411
GQFFR
416
VTKKG
421
DIYNE
426
KELDR
431
EVYPW
436
YNLTV
441
EAKEL
446
DSTGT
451
PTGKE
456
SIVQV
461
HIEVL
466
DENDN
471
APEFA
476
KPYQP
481
KVCEN
486
AVHGQ
491
LVLQI
496
SAIDK
501
DITPR
506
NVKFK
511
FILNT
516
ENNFT
521
LTDNH
526
DNTAN
531
ITVKY
536
GQFDR
541
EHTKV
546
HFLPV
551
VISDN
556
GMPSR
561
TGTST
566
LTVAV
571
CKCNE
576
QGEFT
581
FCEDM
586
AAQVG
591
VSIQA
596
VVAIL
601
LCILT
606
ITVIT
611
LLIFL
616
RRRLR
621
KQARA
626
HGKSV
631
PEIHE
636
QLVTY
641
DEEGG
646
GEMDT
651
TSYDV
656
SVLNS
661
VRRGG
666
AKPPR
671
PALDA
676
RPSLY
681
AQVQK
686
PPRHA
691
PGAHG
696
GPGEM
701
AAMIE
706
VKKDE
711
ADHDG
716
DGPPY
721
DTLHI
726
YGYEG
731
SESIA
736
ESLSS
741
LGTDS
746
SDSDV
751
DYDFL
756
NDWGP
761
RFKML
766
AELYG
771
SDPRE
776
ELLY
781
Mutation Information
DNA mutation:
c.1106C>T
Peptide Range:
363 ~ 371
Mut AA position:
369 (7 in Wild Type peptide)
Alignment
Wild Type:
"ITDVDEPPI
||||||.||
Mutant:
ITDVDELPI"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) CDH5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay