Immunogenicity 11527

summary
Sample ID
3309
Response
Negative
Tumor Type
Melanoma
Gene Symbol
XIRP2
Transcript ID
uc002udy.3
HLA INFO
A*11:01
TCR INFO

No TCR info found!

T cell Tumor cell A*11:01
sequence
Full length protein sequence (3345 aa)
MSPES
1
GHSRI
6
FEATA
11
GPNKP
16
ESGFA
21
EDSAA
26
RGEGV
31
SDLHE
36
VVSLK
41
ERMAR
46
YQAAV
51
SRGDC
56
RSFSA
61
NMMEE
66
SEMCA
71
VPGGL
76
AKVKK
81
QFEDE
86
ITSSR
91
NTFAQ
96
YQYQH
101
QNRSE
106
QEAIH
111
SSQVG
116
TSRSS
121
QEMAR
126
NEQEG
131
SKVQK
136
IDVHG
141
TEMVS
146
HLEKH
151
TEEVN
156
QASQF
161
HQYVQ
166
ETVID
171
TPEDE
176
EIPKV
181
STKLL
186
KEQFE
191
KSAQE
196
KILYS
201
DKEMT
206
TPAKQ
211
IKTES
216
EYEET
221
FKPSS
226
VVSTS
231
STSCV
236
STSQR
241
KETST
246
TRYSD
251
HSVTS
256
STLAQ
261
INATS
266
SGMTE
271
EFPPP
276
PPDVL
281
QTSVD
286
VTAFS
291
QSPEL
296
PSPPR
301
RLPVP
306
KDVYS
311
KQRNL
316
YELNR
321
LYKHI
326
HPELR
331
KNLEK
336
DYISE
341
VSEIV
346
SSQMN
351
SGSSV
356
SADVQ
361
QARYV
366
FENTN
371
DSSQK
376
DLNSE
381
REYLE
386
WDEIL
391
KGEVQ
396
SIRWI
401
FENQP
406
LDSIN
411
NGSPD
416
EGDIS
421
RGIAD
426
QEIIA
431
GGDVK
436
YTTWM
441
FETQP
446
IDTLG
451
AYSSD
456
TVENA
461
EKIPE
466
LARGD
471
VCTAR
476
WMFET
481
RPLDS
486
MNKMH
491
QSQEE
496
SAVTI
501
SKDIT
506
GGDVK
511
TVRYM
516
FETQH
521
LDQLG
526
QLHSV
531
DEVHL
536
LQLRS
541
ELKEI
546
KGNVK
551
RSIKC
556
FETQP
561
LYVIR
566
DGSGQ
571
MLEIK
576
TVHRE
581
DVEKG
586
DVRTA
591
RWMFE
596
TQPLD
601
TINKD
606
ITEIK
611
VVRGI
616
SMEEN
621
VKGGV
626
SKAKW
631
LFETQ
636
PLEKI
641
KESEE
646
VIIEK
651
EKIIG
656
TDVSR
661
KCWMF
666
ETQPL
671
DILKE
676
VPDAD
681
SLQRE
686
EIIGG
691
DVQTT
696
KHLFE
701
TLPIE
706
ALKDS
711
PDIGK
716
LQKIT
721
ASEEE
726
KGDVR
731
HQKWI
736
FETQP
741
LEDIR
746
KDKKE
751
YTRTV
756
KLEEV
761
DRGDV
766
KNYTH
771
IFESN
776
NLIKF
781
DASHK
786
IEVEG
791
VTRGA
796
VELNK
801
SLFET
806
TPLYA
811
IQDPL
816
GKYHQ
821
VKTVQ
826
QEEIV
831
RGDVR
836
SCRWL
841
FETRP
846
IDQFD
851
ESIHK
856
FQIIR
861
GISAQ
866
EIQTG
871
NVKSA
876
KWLFE
881
TQPLD
886
SIKYF
891
SDVEE
896
TESKT
901
EQTRD
906
IVKGD
911
VKTCK
916
WLFET
921
QPMES
926
LYEKV
931
SLMTS
936
SEEIH
941
KGDVK
946
TCTWL
951
FETQP
956
LDTIK
961
DDSET
966
AVKLQ
971
TVKQE
976
EIQGG
981
DVRTA
986
CFLFE
991
TENLD
996
SIQGE
1001
EVKEI
1006
KPVEM
1011
DIQAG
1016
DVSSM
1021
RYKFE
1026
NQSLD
1031
SISSS
1036
SEEVL
1041
KKIKT
1046
LKTED
1051
IQKGN
1056
VLNCR
1061
WLFEN
1066
QPIDK
1071
IKESQ
1076
EGDEC
1081
VKTVT
1086
DIQGG
1091
DVRKG
1096
CFIFE
1101
TFSLD
1106
EIKEE
1111
SDYIS
1116
TKKTI
1121
TEEVI
1126
QGDVK
1131
SYRML
1136
FETQP
1141
LYAIQ
1146
DREGS
1151
YHEVT
1156
TVKKE
1161
EVIHG
1166
DVRGT
1171
RWLFE
1176
TKPLD
1181
SINKS
1186
ETVYV
1191
IKSVT
1196
QEDIQ
1201
KGDVS
1206
SVRYR
1211
FETQP
1216
LDQIS
1221
EESHN
1226
IMPSI
1231
DHIQG
1236
GNVKT
1241
SRQFF
1246
ESENF
1251
DKNNY
1256
IRTVS
1261
VNEIQ
1266
KGNVK
1271
TSTWL
1276
FETHT
1281
MDELR
1286
GEGLE
1291
YENIK
1296
TVTQE
1301
DVQKG
1306
DVKQA
1311
VWLFE
1316
NRTFD
1321
SIMEA
1326
HKGIT
1331
KMTKE
1336
EIPPS
1341
DVKTT
1346
TWLFE
1351
TTPLH
1356
EFNET
1361
RVEKI
1366
EIIGK
1371
SIKET
1376
LEDLY
1381
SQKVI
1386
QAPGI
1391
IIEAD
1396
EIGDV
1401
RMAKY
1406
KLMNQ
1411
ASPEI
1416
QKEEI
1421
IRADL
1426
RNIMV
1431
NLLSK
1436
RDCTE
1441
REILI
1446
SEEEK
1451
GNVNL
1456
TKTQL
1461
LNRST
1466
EFHAE
1471
KEEIV
1476
KGDVQ
1481
QAIKN
1486
LFSEE
1491
RSVKK
1496
GILIQ
1501
EDEKG
1506
DINMT
1511
IYCLL
1516
HENDG
1521
DTIER
1526
EEVIG
1531
GDVKR
1536
TIHNL
1541
LSSTS
1546
NNKIS
1551
ERAKI
1556
DASER
1561
GNVQF
1566
FTTCI
1571
EAGAL
1576
DYLKQ
1581
LHTES
1586
NETLT
1591
AKKQE
1596
GEKEI
1601
IGGDV
1606
EGTKL
1611
LLKKR
1616
QSLVE
1621
RTVSE
1626
TDIIP
1631
GDVHN
1636
TVKVF
1641
MTEPQ
1646
STFGK
1651
IPKEE
1656
IIKGD
1661
LTSTL
1666
NSLSQ
1671
AVNQK
1676
TVTKT
1681
EEIIK
1686
GNMLA
1691
TLKSL
1696
KESSH
1701
RWKES
1706
KQPDA
1711
IPGDI
1716
EKAIE
1721
CLEKA
1726
TNTKT
1731
EILKK
1736
ELLKD
1741
DLETS
1746
LRSLK
1751
EAQRS
1756
FKEVH
1761
KEGVI
1766
KKDAK
1771
AVMAG
1776
SSGEQ
1781
KTDIH
1786
QVAVQ
1791
RNKNS
1796
LLQPK
1801
PGPFE
1806
PAAKW
1811
QGGAD
1816
TLSQT
1821
MGKSC
1826
HGNLV
1831
EERTE
1836
VNLPK
1841
APKGT
1846
VKIVI
1851
DREQN
1856
NDALE
1861
KSLRR
1866
LSNSH
1871
HKSNV
1876
LESGD
1881
KTGVW
1886
TDTTG
1891
EQHLR
1896
DEYMS
1901
RQLTS
1906
TVSVK
1911
NNLTT
1916
KESDR
1921
AVREL
1926
KKDDV
1931
FNSIQ
1936
SAGKT
1941
VGKQQ
1946
TYELR
1951
NDHQK
1956
MEGFH
1961
IKSPK
1966
KTKNI
1971
KILTD
1976
TQSSK
1981
PSPTQ
1986
HPVSM
1991
PVGGT
1996
YDLSG
2001
DFQKQ
2006
TLLKQ
2011
ETKYS
2016
NKDIK
2021
KKNIN
2026
LQPMW
2031
QLLPV
2036
EQDTS
2041
NVTEM
2046
KVSEK
2051
SHNTF
2056
KATNK
2061
KRETD
2066
VHLKS
2071
QDFLM
2076
KTNTS
2081
TGLKM
2086
AMERS
2091
LNPIN
2096
FNPEN
2101
NVKES
2106
ECPLP
2111
PPSPP
2116
PPPPS
2121
NASSE
2126
IEFPL
2131
PPPPP
2136
LMMFP
2141
EKNGF
2146
LPSLS
2151
TEKIK
2156
AEFES
2161
FPGLP
2166
LPPPP
2171
VDEKS
2176
ERESS
2181
SMFLP
2186
PPPPP
2191
TPSQK
2196
PAHLL
2201
SSSAP
2206
EKHSG
2211
DFMQQ
2216
YSQKE
2221
ASNSQ
2226
NSQAK
2231
IITGK
2236
TGVLP
2241
PPTLP
2246
KPKLP
2251
KHIKD
2256
NKNDF
2261
SPKVE
2266
LATSL
2271
SDMEC
2276
KITTS
2281
KDQKK
2286
VMVMT
2291
SSEHT
2296
ETKQN
2301
VISKS
2306
LDERK
2311
QLSID
2316
SANCL
2321
SHTVP
2326
GTSAP
2331
RKKQI
2336
APLIK
2341
SHSFP
2346
ESSGQ
2351
QNPKP
2356
YMRKF
2361
KTPLM
2366
IAEEK
2371
YRQQK
2376
EEIEK
2381
QKQES
2386
SYYNI
2391
VKTQS
2396
QNQHI
2401
TEVEK
2406
EMPLQ
2411
KTNEE
2416
VSLSG
2421
IDSEC
2426
TVVQP
2431
SPGSQ
2436
SNARI
2441
LGVCS
2446
DNQLS
2451
TTSPE
2456
TVAAK
2461
RLHHV
2466
LAASE
2471
DKDKM
2476
KKEVL
2481
QSSRD
2486
IMQSK
2491
SACEI
2496
KQSHQ
2501
ECSTQ
2506
QTQQK
2511
KYLEQ
2516
LHLPQ
2521
SKPIS
2526
PNFKV
2531
KTIKL
2536
PTLDH
2541
TLNET
2546
DHSYE
2551
SHKQQ
2556
SEIDV
2561
QTFTK
2566
KQYLK
2571
TKKTE
2576
ASTEC
2581
SHKQS
2586
LAERH
2591
YQLPK
2596
KEKRV
2601
TVQLP
2606
TESIQ
2611
KNQED
2616
KLKMV
2621
PRKQR
2626
EFSGS
2631
DRGKL
2636
PGSEE
2641
KNQGP
2646
SMIGR
2651
KEERL
2656
ITERK
2661
HEHLK
2666
NKSAP
2671
KVVKQ
2676
KVIDA
2681
HLDSQ
2686
TQNFQ
2691
QTQIQ
2696
TAESK
2701
AEHKK
2706
LPQPY
2711
NSLQE
2716
EKCLE
2721
VKGIQ
2726
EKQVF
2731
SNTKD
2736
SKQEI
2741
TQNKS
2746
FFSSV
2751
KESQR
2756
DDGKG
2761
ALNIV
2766
EFLRK
2771
REELQ
2776
QILSR
2781
VKQFE
2786
AEPNK
2791
SGLKT
2796
FQTLL
2801
NTIPG
2806
WLISE
2811
DKREY
2816
AVHIA
2821
MENNL
2826
EKVKE
2831
EITHI
2836
KTQAE
2841
DMLVS
2846
YENII
2851
QTAMM
2856
SSKTG
2861
KPGNK
2866
PTSLD
2871
ETSSK
2876
VSNVH
2881
VSNNK
2886
NSEQK
2891
ENKIA
2896
KEKTV
2901
QHQVA
2906
AHHEA
2911
TVRSH
2916
VKTHQ
2921
EIKLD
2926
DSNIP
2931
PPSLK
2936
TRPPS
2941
PTFIT
2946
IESTA
2951
RRTEN
2956
PTKNE
2961
LSQSP
2966
KKDSY
2971
VEPPP
2976
RRPMS
2981
QKSEI
2986
HRANT
2991
SPSPP
2996
RSRSE
3001
QLVRL
3006
KDTTA
3011
KLSKG
3016
AIPCP
3021
AATPV
3026
PIVEK
3031
RSEII
3036
MSPAT
3041
LRRQI
3046
KIETR
3051
GRDSP
3056
PTITI
3061
PVNIN
3066
HAASG
3071
SFRES
3076
VDAQE
3081
EIRKV
3086
EKRAT
3091
YVHKD
3096
GLNST
3101
DHMVP
3106
DTESY
3111
DAVEI
3116
IRKVA
3121
VPPRL
3126
SEHTQ
3131
RYEAA
3136
NRTVQ
3141
MAENF
3146
VNDPE
3151
NEINR
3156
WFREF
3161
EHGPV
3166
SEAKS
3171
NRRVY
3176
AKGET
3181
NHNIQ
3186
QESRT
3191
FCKEE
3196
FGLTS
3201
LGNTS
3206
FTDFS
3211
CKHPR
3216
ELREK
3221
IPVKQ
3226
PRICS
3231
ETRSL
3236
SEHFS
3241
GMDAF
3246
ESQIV
3251
ESKMK
3256
TSSSH
3261
SSEAG
3266
KSGCD
3271
FKHAP
3276
PTYED
3281
VIAGH
3286
ILDIS
3291
DSPKE
3296
VRKNF
3301
QKTWQ
3306
ESGRV
3311
FKGLG
3316
YATAD
3321
ASATE
3326
MRTTF
3331
QEESA
3336
FISGK
3341
Mutation Information
DNA mutation:
c.6281G>A
Peptide Range:
2085 ~ 2094
Mut AA position:
2094 (10 in Wild Type peptide)
Alignment
Wild Type:
"STGLKMAMER
|||||||||.
Mutant:
STGLKMAMEK"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

TILs

APC Type

COS7

Assay

IFNg ELISPOT assay