Immunogenicity 11528
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
LRP2
Transcript ID
uc002ues.3
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (4655 aa)
MDRGP
1
AAVAC
6
TLLLA
11
LVACL
16
APASG
21
QECDS
26
AHFRC
31
GSGHC
36
IPADW
41
RCDGT
46
KDCSD
51
DADEI
56
GCAVV
61
TCQQG
66
YFKCQ
71
SEGQC
76
IPNSW
81
VCDQD
86
QDCDD
91
GSDER
96
QDCSQ
101
STCSS
106
HQITC
111
SNGQC
116
IPSEY
121
RCDHV
126
RDCPD
131
GADEN
136
DCQYP
141
TCEQL
146
TCDNG
151
ACYNT
156
SQKCD
161
WKVDC
166
RDSSD
171
EINCT
176
EICLH
181
NEFSC
186
GNGEC
191
IPRAY
196
VCDHD
201
NDCQD
206
GSDEH
211
ACNYP
216
TCGGY
221
QFTCP
226
SGRCI
231
YQNWV
236
CDGED
241
DCKDN
246
GDEDG
251
CESGP
256
HDVHK
261
CSPRE
266
WSCPE
271
SGRCI
276
SIYKV
281
CDGIL
286
DCPGR
291
EDENN
296
TSTGK
301
YCSMT
306
LCSAL
311
NCQYQ
316
CHETP
321
YGGAC
326
FCPPG
331
YIINH
336
NDSRT
341
CVEFD
346
DCQIW
351
GICDQ
356
KCESR
361
PGRHL
366
CHCEE
371
GYILE
376
RGQYC
381
KANDS
386
FGEAS
391
IIFSN
396
GRDLL
401
IGDIH
406
GRSFR
411
ILVES
416
QNRGV
421
AVGVA
426
FHYHL
431
QRVFW
436
TDTVQ
441
NKVFS
446
VDING
451
LNIQE
456
VLNVS
461
VETPE
466
NLAVD
471
WVNNK
476
IYLVE
481
TKVNR
486
IDMVN
491
LDGSY
496
RVTLI
501
TENLG
506
HPRGI
511
AVDPT
516
VGYLF
521
FSDWE
526
SLSGE
531
PKLER
536
AFMDG
541
SNRKD
546
LVKTK
551
LGWPA
556
GVTLD
561
MISKR
566
VYWVD
571
SRFDY
576
IETVT
581
YDGIQ
586
RKTVV
591
HGGSL
596
IPHPF
601
GVSLF
606
EGQVF
611
FTDWT
616
KMAVL
621
KANKF
626
TETNP
631
QVYYQ
636
ASLRP
641
YGVTV
646
YHSLR
651
QPYAT
656
NPCKD
661
NNGGC
666
EQVCV
671
LSHRT
676
DNDGL
681
GFRCK
686
CTFGF
691
QLDTD
696
ERHCI
701
AVQNF
706
LIFSS
711
QVAIR
716
GIPFT
721
LSTQE
726
DVMVP
731
VSGNP
736
SFFVG
741
IDFDA
746
QDSTI
751
FFSDM
756
SKHMI
761
FKQKI
766
DGTGR
771
EILAA
776
NRVEN
781
VESLA
786
FDWIS
791
KNLYW
796
TDSHY
801
KSISV
806
MRLAD
811
KTRRT
816
VVQYL
821
NNPRS
826
VVVHP
831
FAGYL
836
FFTDW
841
FRPAK
846
IMRAW
851
SDGSH
856
LLPVI
861
NTTLG
866
WPNGL
871
AIDWA
876
ASRLY
881
WVDAY
886
FDKIE
891
HSTFD
896
GLDRR
901
RLGHI
906
EQMTH
911
PFGLA
916
IFGEH
921
LFFTD
926
WRLGA
931
IIRVR
936
KADGG
941
EMTVI
946
RSGIA
951
YILHL
956
KSYDV
961
NIQTG
966
SNACN
971
QPTHP
976
NGDCS
981
HFCFP
986
VPNFQ
991
RVCGC
996
PYGMR
1001
LASNH
1006
LTCEG
1011
DPTNE
1016
PPTEQ
1021
CGLFS
1026
FPCKN
1031
GRCVP
1036
NYYLC
1041
DGVDD
1046
CHDNS
1051
DEQLC
1056
GTLNN
1061
TCSSS
1066
AFTCG
1071
HGECI
1076
PAHWR
1081
CDKRN
1086
DCVDG
1091
SDEHN
1096
CPTHA
1101
PASCL
1106
DTQYT
1111
CDNHQ
1116
CISKN
1121
WVCDT
1126
DNDCG
1131
DGSDE
1136
KNCNS
1141
TETCQ
1146
PSQFN
1151
CPNHR
1156
CIDLS
1161
FVCDG
1166
DKDCV
1171
DGSDE
1176
VGCVL
1181
NCTAS
1186
QFKCA
1191
SGDKC
1196
IGVTN
1201
RCDGV
1206
FDCSD
1211
NSDEA
1216
GCPTR
1221
PPGMC
1226
HSDEF
1231
QCQED
1236
GICIP
1241
NFWEC
1246
DGHPD
1251
CLYGS
1256
DEHNA
1261
CVPKT
1266
CPSSY
1271
FHCDN
1276
GNCIH
1281
RAWLC
1286
DRDND
1291
CGDMS
1296
DEKDC
1301
PTQPF
1306
RCPSW
1311
QWQCL
1316
GHNIC
1321
VNLSV
1326
VCDGI
1331
FDCPN
1336
GTDES
1341
PLCNG
1346
NSCSD
1351
FNGGC
1356
THECV
1361
QEPFG
1366
AKCLC
1371
PLGFL
1376
LANDS
1381
KTCED
1386
IDECD
1391
ILGSC
1396
SQHCY
1401
NMRGS
1406
FRCSC
1411
DTGYM
1416
LESDG
1421
RTCKV
1426
TASES
1431
LLLLV
1436
ASQNK
1441
IIADS
1446
VTSQV
1451
HNIYS
1456
LVENG
1461
SYIVA
1466
VDFDS
1471
ISGRI
1476
FWSDA
1481
TQGKT
1486
WSAFQ
1491
NGTDR
1496
RVVFD
1501
SSIIL
1506
TETIA
1511
IDWVG
1516
RNLYW
1521
TDYAL
1526
ETIEV
1531
SKIDG
1536
SHRTV
1541
LISKN
1546
LTNPR
1551
GLALD
1556
PRMNE
1561
HLLFW
1566
SDWGH
1571
HPRIE
1576
RASMD
1581
GSMRT
1586
VIVQD
1591
KIFWP
1596
CGLTI
1601
DYPNR
1606
LLYFM
1611
DSYLD
1616
YMDFC
1621
DYNGH
1626
HRRQV
1631
IASDL
1636
IIRHP
1641
YALTL
1646
FEDSV
1651
YWTDR
1656
ATRRV
1661
MRANK
1666
WHGGN
1671
QSVVM
1676
YNIQW
1681
PLGIV
1686
AVHPS
1691
KQPNS
1696
VNPCA
1701
FSRCS
1706
HLCLL
1711
SSQGP
1716
HFYSC
1721
VCPSG
1726
WSLSP
1731
DLLNC
1736
LRDDQ
1741
PFLIT
1746
VRQHI
1751
IFGIS
1756
LNPEV
1761
KSNDA
1766
MVPIA
1771
GIQNG
1776
LDVEF
1781
DDAEQ
1786
YIYWV
1791
ENPGE
1796
IHRVK
1801
TDGTN
1806
RTVFA
1811
SISMV
1816
GPSMN
1821
LALDW
1826
ISRNL
1831
YSTNP
1836
RTQSI
1841
EVLTL
1846
HGDIR
1851
YRKTL
1856
IANDG
1861
TALGV
1866
GFPIG
1871
ITVDP
1876
ARGKL
1881
YWSDQ
1886
GTDSG
1891
VPAKI
1896
ASANM
1901
DGTSV
1906
KTLFT
1911
GNLEH
1916
LECVT
1921
LDIEE
1926
QKLYW
1931
AVTGR
1936
GVIER
1941
GNVDG
1946
TDRMI
1951
LVHQL
1956
SHPWG
1961
IAVHD
1966
SFLYY
1971
TDEQY
1976
EVIER
1981
VDKAT
1986
GANKI
1991
VLRDN
1996
VPNLR
2001
GLQVY
2006
HRRNA
2011
AESSN
2016
GCSNN
2021
MNACQ
2026
QICLP
2031
VPGGL
2036
FSCAC
2041
ATGFK
2046
LNPDN
2051
RSCSP
2056
YNSFI
2061
VVSML
2066
SAIRG
2071
FSLEL
2076
SDHSE
2081
TMVPV
2086
AGQGR
2091
NALHV
2096
DVDVS
2101
SGFIY
2106
WCDFS
2111
SSVAS
2116
DNAIR
2121
RIKPD
2126
GSSLM
2131
NIVTH
2136
GIGEN
2141
GVRGI
2146
AVDWV
2151
AGNLY
2156
FTNAF
2161
VSETL
2166
IEVLR
2171
INTTY
2176
RRVLL
2181
KVTVD
2186
MPRHI
2191
VVDPK
2196
NRYLF
2201
WADYG
2206
QRPKI
2211
ERSFL
2216
DCTNR
2221
TVLVS
2226
EGIVT
2231
PRGLA
2236
VDRSD
2241
GYVYW
2246
VDDSL
2251
DIIAR
2256
IRING
2261
ENSEV
2266
IRYGS
2271
RYPTP
2276
YGITV
2281
FENSI
2286
IWVDR
2291
NLKKI
2296
FQASK
2301
EPENT
2306
EPPTV
2311
IRDNI
2316
NWLRD
2321
VTIFD
2326
KQVQP
2331
RSPAE
2336
VNNNP
2341
CLENN
2346
GGCSH
2351
LCFAL
2356
PGLHT
2361
PKCDC
2366
AFGTL
2371
QSDGK
2376
NCAIS
2381
TENFL
2386
IFALS
2391
NSLRS
2396
LHLDP
2401
ENHSP
2406
PFQTI
2411
NVERT
2416
VMSLD
2421
YDSVS
2426
DRIYF
2431
TQNLA
2436
SGVGQ
2441
ISYAT
2446
LSSGI
2451
HTPTV
2456
IASGI
2461
GTADG
2466
IAFDW
2471
ITRRI
2476
YYSDY
2481
LNQMI
2486
NSMAE
2491
DGSNR
2496
TVIAR
2501
VPKPR
2506
AIVLD
2511
PCQGY
2516
LYWAD
2521
WDTHA
2526
KIERA
2531
TLGGN
2536
FRVPI
2541
VNSSL
2546
VMPSG
2551
LTLDY
2556
EEDLL
2561
YWVDA
2566
SLQRI
2571
ERSTL
2576
TGVDR
2581
EVIVN
2586
AAVHA
2591
FGLTL
2596
YGQYI
2601
YWTDL
2606
YTQRI
2611
YRANK
2616
YDGSG
2621
QIAMT
2626
TNLLS
2631
QPRGI
2636
NTVVK
2641
NQKQQ
2646
CNNPC
2651
EQFNG
2656
GCSHI
2661
CAPGP
2666
NGAEC
2671
QCPHE
2676
GNWYL
2681
ANNRK
2686
HCIVD
2691
NGERC
2696
GASSF
2701
TCSNG
2706
RCISE
2711
EWKCD
2716
NDNDC
2721
GDGSD
2726
EMESV
2731
CALHT
2736
CSPTA
2741
FTCAN
2746
GRCVQ
2751
YSYRC
2756
DYYND
2761
CGDGS
2766
DEAGC
2771
LFRDC
2776
NATTE
2781
FMCNN
2786
RRCIP
2791
REFIC
2796
NGVDN
2801
CHDNN
2806
TSDEK
2811
NCPDR
2816
TCQSG
2821
YTKCH
2826
NSNIC
2831
IPRVY
2836
LCDGD
2841
NDCGD
2846
NSDEN
2851
PTYCT
2856
THTCS
2861
SSEFQ
2866
CASGR
2871
CIPQH
2876
WYCDQ
2881
ETDCF
2886
DASDE
2891
PASCG
2896
HSERT
2901
CLADE
2906
FKCDG
2911
GRCIP
2916
SEWIC
2921
DGDND
2926
CGDMS
2931
DEDKR
2936
HQCQN
2941
QNCSD
2946
SEFLC
2951
VNDRP
2956
PDRRC
2961
IPQSW
2966
VCDGD
2971
VDCTD
2976
GYDEN
2981
QNCTR
2986
RTCSE
2991
NEFTC
2996
GYGLC
3001
IPKIF
3006
RCDRH
3011
NDCGD
3016
YSDER
3021
GCLYQ
3026
TCQQN
3031
QFTCQ
3036
NGRCI
3041
SKTFV
3046
CDEDN
3051
DCGDG
3056
SDELM
3061
HLCHT
3066
PEPTC
3071
PPHEF
3076
KCDNG
3081
RCIEM
3086
MKLCN
3091
HLDDC
3096
LDNSD
3101
EKGCG
3106
INECH
3111
DPSIS
3116
GCDHN
3121
CTDTL
3126
TSFYC
3131
SCRPG
3136
YKLMS
3141
DKRTC
3146
VDIDE
3151
CTEMP
3156
FVCSQ
3161
KCENV
3166
IGSYI
3171
CKCAP
3176
GYLRE
3181
PDGKT
3186
CRQNS
3191
NIEPY
3196
LIFSN
3201
RYYLR
3206
NLTID
3211
GYFYS
3216
LILEG
3221
LDNVV
3226
ALDFD
3231
RVEKR
3236
LYWID
3241
TQRQV
3246
IERMF
3251
LNKTN
3256
KETII
3261
NHRLP
3266
AAESL
3271
AVDWV
3276
SRKLY
3281
WLDAR
3286
LDGLF
3291
VSDLN
3296
GGHRR
3301
MLAQH
3306
CVDAN
3311
NTFCF
3316
DNPRG
3321
LALHP
3326
QYGYL
3331
YWADW
3336
GHRAY
3341
IGRVG
3346
MDGTN
3351
KSVII
3356
STKLE
3361
WPNGI
3366
TIDYT
3371
NDLLY
3376
WADAH
3381
LGYIE
3386
YSDLE
3391
GHHRH
3396
TVYDG
3401
ALPHP
3406
FAITI
3411
FEDTI
3416
YWTDW
3421
NTRTV
3426
EKGNK
3431
YDGSN
3436
RQTLV
3441
NTTHR
3446
PFDIH
3451
VYHPY
3456
RQPIV
3461
SNPCG
3466
TNNGG
3471
CSHLC
3476
LIKPG
3481
GKGFT
3486
CECPD
3491
DFRTL
3496
QLSGS
3501
TYCMP
3506
MCSST
3511
QFLCA
3516
NNEKC
3521
IPIWW
3526
KCDGQ
3531
KDCSD
3536
GSDEL
3541
ALCPQ
3546
RFCRL
3551
GQFQC
3556
SDGNC
3561
TSPQT
3566
LCNAH
3571
QNCPD
3576
GSDED
3581
RLLCE
3586
NHHCD
3591
SNEWQ
3596
CANKR
3601
CIPES
3606
WQCDT
3611
FNDCE
3616
DNSDE
3621
DSSHC
3626
ASRTC
3631
RPGQF
3636
RCANG
3641
RCIPQ
3646
AWKCD
3651
VDNDC
3656
GDHSD
3661
EPIEE
3666
CMSSA
3671
HLCDN
3676
FTEFS
3681
CKTNY
3686
RCIPK
3691
WAVCN
3696
GVDDC
3701
RDNSD
3706
EQGCE
3711
ERTCH
3716
PVGDF
3721
RCKNH
3726
HCIPL
3731
RWQCD
3736
GQNDC
3741
GDNSD
3746
EENCA
3751
PRECT
3756
ESEFR
3761
CVNQQ
3766
CIPSR
3771
WICDH
3776
YNDCG
3781
DNSDE
3786
RDCEM
3791
RTCHP
3796
EYFQC
3801
TSGHC
3806
VHSEL
3811
KCDGS
3816
ADCLD
3821
ASDEA
3826
DCPTR
3831
FPDGA
3836
YCQAT
3841
MFECK
3846
NHVCI
3851
PPYWK
3856
CDGDD
3861
DCGDG
3866
SDEEL
3871
HLCLD
3876
VPCNS
3881
PNRFR
3886
CDNNR
3891
CIYSH
3896
EVCNG
3901
VDDCG
3906
DGTDE
3911
TEEHC
3916
RKPTP
3921
KPCTE
3926
YEYKC
3931
GNGHC
3936
IPHDN
3941
VCDDA
3946
DDCGD
3951
WSDEL
3956
GCNKG
3961
KERTC
3966
AENIC
3971
EQNCT
3976
QLNEG
3981
GFICS
3986
CTAGF
3991
ETNVF
3996
DRTSC
4001
LDINE
4006
CEQFG
4011
TCPQH
4016
CRNTK
4021
GSYEC
4026
VCADG
4031
FTSMS
4036
DRPGK
4041
RCAAE
4046
GSSPL
4051
LLLPD
4056
NVRIR
4061
KYNLS
4066
SERFS
4071
EYLQD
4076
EEYIQ
4081
AVDYD
4086
WDPKD
4091
IGLSV
4096
VYYTV
4101
RGEGS
4106
RFGAI
4111
KRAYI
4116
PNFES
4121
GRNNL
4126
VQEVD
4131
LKLKY
4136
VMQPD
4141
GIAVD
4146
WVGRH
4151
IYWSD
4156
VKNKR
4161
IEVAK
4166
LDGRY
4171
RKWLI
4176
STDLD
4181
QPAAI
4186
AVNPK
4191
LGLMF
4196
WTDWG
4201
KEPKI
4206
ESAWM
4211
NGEDR
4216
NILVF
4221
EDLGW
4226
PTGLS
4231
IDYLN
4236
NDRIY
4241
WSDFK
4246
EDVIE
4251
TIKYD
4256
GTDRR
4261
VIAKE
4266
AMNPY
4271
SLDIF
4276
EDQLY
4281
WISKE
4286
KGEVW
4291
KQNKF
4296
GQGKK
4301
EKTLV
4306
VNPWL
4311
TQVRI
4316
FHQLR
4321
YNKSV
4326
PNLCK
4331
QICSH
4336
LCLLR
4341
PGGYS
4346
CACPQ
4351
GSSFI
4356
EGSTT
4361
ECDAA
4366
IELPI
4371
NLPPP
4376
CRCMH
4381
GGNCY
4386
FDETD
4391
LPKCK
4396
CPSGY
4401
TGKYC
4406
EMAFS
4411
KGISP
4416
GTTAV
4421
AVLLT
4426
ILLIV
4431
VIGAL
4436
AIAGF
4441
FHYRR
4446
TGSLL
4451
PALPK
4456
LPSLS
4461
SLVKP
4466
SENGN
4471
GVTFR
4476
SGADL
4481
NMDIG
4486
VSGFG
4491
PETAI
4496
DRSMA
4501
MSEDF
4506
VMEMG
4511
KQPII
4516
FENPM
4521
YSARD
4526
SAVKV
4531
VQPIQ
4536
VTVSE
4541
NVDNK
4546
NYGSP
4551
INPSE
4556
IVPET
4561
NPTSP
4566
AADGT
4571
QVTKW
4576
NLFKR
4581
KSKQT
4586
TNFEN
4591
PIYAQ
4596
MENEQ
4601
KESVA
4606
ATPPP
4611
SPSLP
4616
AKPKP
4621
PSRRD
4626
PTPTY
4631
SATED
4636
TFKDT
4641
ANLVK
4646
EDSEV
4651
Mutation Information
DNA mutation:
c.10030C>T
Peptide Range:
3337 ~ 3345
Mut AA position:
3344 (8 in Wild Type peptide)
Alignment
Wild Type:
"WADWGHRAY
|||||||.|
Mutant:
WADWGHRTY"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) LRP2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay