Immunogenicity 11558
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HEG1
Transcript ID
uc003ehs.4
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1381 aa)
MASPR
1
ASRWP
6
PPLLL
11
LLLPL
16
LLLPP
21
AAPGT
26
RDPPP
31
SPARR
36
ALSLA
41
PLAGA
46
GLELQ
51
LERRP
56
EREPP
61
PTPPR
66
ERRGP
71
ATPGP
76
SYRAP
81
EPGAA
86
TQRGP
91
SGRAP
96
RGGSA
101
DAAWK
106
HWPES
111
NTEAH
116
VENIT
121
FYQNQ
126
EDFST
131
VSSKE
136
GVMVQ
141
TSGKS
146
HAASD
151
APENL
156
TLLAE
161
TADAR
166
GRSGS
171
SSRTN
176
FTILP
181
VGYSL
186
EIATA
191
LTSQS
196
GNLAS
201
ESLHL
206
PSSSS
211
EFDER
216
IAAFQ
221
TKSGT
226
ASEMG
231
TERAM
236
GLSEE
241
WTVHS
246
QEATT
251
SAWSP
256
SFLPA
261
LEMGE
266
LTTPS
271
RKRNS
276
SGPDL
281
SWLHF
286
YRTAA
291
SSPLL
296
DLSSS
301
SESTE
306
KLNNS
311
TGLQS
316
SSVSQ
321
TKTMH
326
VATVF
331
TDGGP
336
RTLRS
341
LTVSL
346
GPVSK
351
TEGFP
356
KDSRI
361
ATTSS
366
SVLLS
371
PSAVE
376
SRRNS
381
RVTGN
386
PGDEE
391
FIEPS
396
TENEF
401
GLTSL
406
RWQND
411
SPTFG
416
EHQLA
421
SSSEV
426
QNGSP
431
MSQTE
436
TVSRS
441
VAPMR
446
GGEIT
451
AHWLL
456
TNSTT
461
SADVT
466
GSSAS
471
YPEGV
476
NASVL
481
TQFSD
486
STVQS
491
GGSHT
496
ALGDR
501
SYSES
506
SSTSS
511
SESLN
516
SSAPR
521
GERSI
526
AGISY
531
GQVRG
536
TAIEQ
541
RTSSD
546
HTDHT
551
YLSST
556
FTKGE
561
RALLS
566
ITDNS
571
SSSDI
576
VESST
581
SYIKI
586
SNSSH
591
SEYSS
596
FFHAQ
601
TERSN
606
ISSYD
611
GEYAQ
616
PSTES
621
PVLHT
626
SNLPS
631
YTPTI
636
NMPNT
641
SVVLD
646
TDAEF
651
VSDSS
656
SSSSS
661
SSSSS
666
SSGPP
671
LPLPS
676
VSQSH
681
HLFSS
686
ILPST
691
RASVH
696
LLKST
701
SDAST
706
PWSSS
711
PSPLP
716
VSLTT
721
STSAP
726
LSVSQ
731
TTLPQ
736
SSSTP
741
VLPRA
746
RETPV
751
TSFQT
756
STMTS
761
FMTML
766
HSSQT
771
ADLKS
776
QSTPH
781
QEKVI
786
TESKS
791
PSLVS
796
LPTES
801
TKAVT
806
TNSPL
811
PPSLT
816
ESSTE
821
QTLPA
826
TSTNL
831
AQMSP
836
TFTTT
841
ILKTS
846
QPLMT
851
TPGTL
856
SSTAS
861
LVTGP
866
IAVQT
871
TAGKQ
876
LSLTH
881
PEILV
886
PQIST
891
EGGIS
896
TERNR
901
VIVDA
906
TTGLI
911
PLTSV
916
PTSAK
921
EMTTK
926
LGVTA
931
EYSPA
936
SRSLG
941
TSPSP
946
QTTVV
951
STAED
956
LAPKS
961
ATFAV
966
QSSTQ
971
SPTTV
976
SSSAS
981
VNSCA
986
VNPCL
991
HNGEC
996
VADNT
1001
SRGYH
1006
CRCPP
1011
SWQGD
1016
DCSVD
1021
VNECL
1026
SNPCP
1031
STAMC
1036
NNTQG
1041
SFICK
1046
CPVGY
1051
QLEKG
1056
ICNLV
1061
RTFVT
1066
EFKLK
1071
RTFLN
1076
TTVEK
1081
HSDLQ
1086
EVENE
1091
ITKTL
1096
NMCFS
1101
ALPSY
1106
IRSTV
1111
HASRE
1116
SNAVV
1121
ISLQT
1126
TFSLA
1131
SNVTL
1136
FDLAD
1141
RMQKC
1146
VNSCK
1151
SSAEV
1156
CQLLG
1161
SQRRI
1166
FRAGS
1171
LCKRK
1176
SPECD
1181
KDTSI
1186
CTDLD
1191
GVALC
1196
QCKSG
1201
YFQFN
1206
KMDHS
1211
CRACE
1216
DGYRL
1221
ENETC
1226
MSCPF
1231
GLGGL
1236
NCGNP
1241
YQLIT
1246
VVIAA
1251
AGGGL
1256
LLILG
1261
IALIV
1266
TCCRK
1271
NKNDI
1276
SKLIF
1281
KSGDF
1286
QMSPY
1291
AEYPK
1296
NPRSQ
1301
EWGRE
1306
AIEMH
1311
ENGST
1316
KNLLQ
1321
MTDVY
1326
YSPTS
1331
VRNPE
1336
LERNG
1341
LYPAY
1346
TGLPG
1351
SRHSC
1356
IFPGQ
1361
YNPSF
1366
ISDES
1371
RRRDY
1376
F
1381
Mutation Information
DNA mutation:
c.1807G>A
Peptide Range:
595 ~ 603
Mut AA position:
603 (9 in Wild Type peptide)
Alignment
Wild Type:
"HSEYSSFFH
||||||||.
Mutant:
HSEYSSFFY"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) HEG1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay