Immunogenicity 116
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
SPTA1
Transcript ID
uc001fst.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (2419 aa)
MEQFP
1
KETVV
6
ESSGP
11
KVLET
16
AEEIQ
21
ERRQE
26
VLTRY
31
QSFKE
36
RVAER
41
GQKLE
46
DSYHL
51
QVFKR
56
DADDL
61
GKWIM
66
EKVNI
71
LTDKS
76
YEDPT
81
NIQGK
86
YQKHQ
91
SLEAE
96
VQTKS
101
RLMSE
106
LEKTR
111
EERFT
116
MGHSA
121
HEETK
126
AHIEE
131
LRHLW
136
DLLLE
141
LTLEK
146
GDQLL
151
RALKF
156
QQYVQ
161
ECADI
166
LEWIG
171
DKEAI
176
ATSVE
181
LGEDW
186
ERTEV
191
LHKKF
196
EDFQV
201
ELVAK
206
EGRVV
211
EVNQY
216
ANECA
221
EENHP
226
DLPLI
231
QSKQN
236
EVNAA
241
WERLR
246
GLALQ
251
RQKAL
256
SNAAN
261
LQRFK
266
RDVTE
271
AIQWI
276
KEKEP
281
VLTSE
286
DYGKD
291
LVASE
296
GLFHS
301
HKGLE
306
RNLAV
311
MSDKV
316
KELCA
321
KAEKL
326
TLSHP
331
SDAPQ
336
IQEMK
341
EDLVS
346
SWEHI
351
RALAT
356
SRYEK
361
LQATY
366
WYHRF
371
SSDFD
376
ELSGW
381
MNEKT
386
AAINA
391
DELPT
396
DVAGG
401
EVLLD
406
RHQQH
411
KHEID
416
SYDDR
421
FQSAD
426
ETGQD
431
LVNAN
436
HEASD
441
EVREK
446
MEILD
451
NNWTA
456
LLELW
461
DERHR
466
QYEQC
471
LDFHL
476
FYRDS
481
EQVDS
486
WMSRQ
491
EAFLE
496
NEDLG
501
NSLGS
506
AEALL
511
QKHED
516
FEEAF
521
TAQEE
526
KIITV
531
DKTAT
536
KLIGD
541
DHYDS
546
ENIKA
551
IRDGL
556
LARRD
561
ALREK
566
AATRR
571
RLLKE
576
SLLLQ
581
KLYED
586
SDDLK
591
NWINK
596
KKKLA
601
DDEDY
606
KDIQN
611
LKSRV
616
QKQQV
621
FEKEL
626
AVNKT
631
QLENI
636
QKTGQ
641
EMIEG
646
GHYAS
651
DNVTT
656
RLSEV
661
ASLWE
666
ELLEA
671
TKQKG
676
TQLHE
681
ANQQL
686
QFENN
691
AEDLQ
696
RWLED
701
VEWQV
706
TSEDY
711
GKGLA
716
EVQNR
721
LRKHG
726
LLESA
731
VAARQ
736
DQVDI
741
LTDLA
746
AYFEE
751
IGHPD
756
SKDIR
761
ARQES
766
LVCRF
771
EALKE
776
PLATR
781
KKKLL
786
DLLHL
791
QLICR
796
DTEDE
801
EAWIQ
806
ETEPS
811
ATSTY
816
LGKDL
821
IASKK
826
LLNRH
831
RVILE
836
NIASH
841
EPRIQ
846
EITER
851
GNKMV
856
EEGHF
861
AAEDV
866
ASRVK
871
SLNQN
876
MESLR
881
ARAAR
886
RQNDL
891
EANVQ
896
FQQYL
901
ADLHE
906
AETWI
911
REKEP
916
IVDNT
921
NYGAD
926
EEAAG
931
ALLKK
936
HEAFL
941
LDLNS
946
FGDSM
951
KALRN
956
QANAC
961
QQQQA
966
APVEG
971
VAGEQ
976
RVMAL
981
YDFQA
986
RSPRE
991
VTMKK
996
GDVLT
1001
LLSSI
1006
NKDWW
1011
KVEAA
1016
DHQGI
1021
VPAVY
1026
VRRLA
1031
HDEFP
1036
MLPQR
1041
RREEP
1046
GNITQ
1051
RQEQI
1056
ENQYR
1061
SLLDR
1066
AEERR
1071
RRLLQ
1076
RYNEF
1081
LLAYE
1086
AGDML
1091
EWIQE
1096
KKAEN
1101
TGVEL
1106
DDVWE
1111
LQKKF
1116
DEFQK
1121
DLNTN
1126
EPRLR
1131
DINKV
1136
ADDLL
1141
FEGLL
1146
TPEGA
1151
QIRQE
1156
LNSRW
1161
GSLQR
1166
LADEQ
1171
RQLLG
1176
SAHAV
1181
EVFHR
1186
EADDT
1191
KEQIE
1196
KKCQA
1201
LSAAD
1206
PGSDL
1211
FSVQA
1216
LQRRH
1221
EGFER
1226
DLVPL
1231
GDKVT
1236
ILGET
1241
AERLS
1246
ESHPD
1251
ATEDL
1256
QRQKM
1261
ELNEA
1266
WEDLQ
1271
GRTKD
1276
RKESL
1281
NEAQK
1286
FYLFL
1291
SKARD
1296
LQNWI
1301
SSIGG
1306
MVSSQ
1311
ELAED
1316
LTGIE
1321
ILLER
1326
HQEHR
1331
ADMEA
1336
EAPTF
1341
QALED
1346
FSAEL
1351
IDSGH
1356
HASPE
1361
IEKKL
1366
QAVKL
1371
ERDDL
1376
EKAWE
1381
KRKKI
1386
LDQCL
1391
ELQMF
1396
QGNCD
1401
QVESW
1406
MVARE
1411
NSLRS
1416
DDKSS
1421
LDSLE
1426
ALMKK
1431
RDDLD
1436
KAITA
1441
QEGKI
1446
TDLEH
1451
FAESL
1456
IADEH
1461
YAKEE
1466
IATRL
1471
QRVLD
1476
RWKAL
1481
KAQLI
1486
DERTK
1491
LGDYA
1496
NLKQF
1501
YRDLE
1506
ELEEW
1511
ISEML
1516
PTACD
1521
ESYKD
1526
ATNIQ
1531
RKYLK
1536
HQTFA
1541
HEVDG
1546
RSEQV
1551
HGVIN
1556
LGNSL
1561
IECSA
1566
CDGNE
1571
EAMKE
1576
QLEQL
1581
KEHWD
1586
HLLER
1591
TNDKG
1596
KKLNE
1601
ASRQQ
1606
RFNTS
1611
IRDFE
1616
FWLSE
1621
AETLL
1626
AMKDQ
1631
ARDLA
1636
SAGNL
1641
LKKHQ
1646
LLERE
1651
MLARE
1656
DALKD
1661
LNTLA
1666
EDLLS
1671
SGTFN
1676
VDQIV
1681
KKKDN
1686
VNKRF
1691
LNVQE
1696
LAAAH
1701
HEKLK
1706
EAYAL
1711
FQFFQ
1716
DLDDE
1721
ESWIE
1726
EKLIR
1731
VSSQD
1736
YGRDL
1741
QGVQN
1746
LLKKH
1751
KRLEG
1756
ELVAH
1761
EPAIQ
1766
NVLDM
1771
AEKLK
1776
DKAAV
1781
GQEEI
1786
QLRLA
1791
QFVEH
1796
WEKLK
1801
ELAKA
1806
RGLKL
1811
EESLE
1816
YLQFM
1821
QNAEE
1826
EEAWI
1831
NEKNA
1836
LAVRG
1841
DCGDT
1846
LAATQ
1851
SLLMK
1856
HEALE
1861
NDFAV
1866
HETRV
1871
QNVCA
1876
QGEDI
1881
LNKVL
1886
QEESQ
1891
NKEIS
1896
SKIEA
1901
LNEKT
1906
PSLAK
1911
AIAAW
1916
KLQLE
1921
DDYAF
1926
QEFNW
1931
KADVV
1936
EAWIA
1941
DKETS
1946
LKTNG
1951
NGADL
1956
GDFLT
1961
LLAKQ
1966
DTLDA
1971
SLQSF
1976
QQERL
1981
PEITD
1986
LKDKL
1991
ISAQH
1996
NQSKA
2001
IEERY
2006
AALLK
2011
RWEQL
2016
LEASA
2021
VHRQK
2026
LLEKQ
2031
LPLQK
2036
AEDLF
2041
VEFAH
2046
KASAL
2051
NNWCE
2056
KMEEN
2061
LSEPV
2066
HCVSL
2071
NEIRQ
2076
LQKDH
2081
EDFLA
2086
SLARA
2091
QADFK
2096
CLLEL
2101
DQQIK
2106
ALGVP
2111
SSPYT
2116
WLTVE
2121
VLERT
2126
WKHLS
2131
DIIEE
2136
REQEL
2141
QKEEA
2146
RQVKN
2151
FEMCQ
2156
EFEQN
2161
ASTFL
2166
QWILE
2171
TRAYF
2176
LDGSL
2181
LKETG
2186
TLESQ
2191
LEANK
2196
RKQKE
2201
IQAMK
2206
RQLTK
2211
IVDLG
2216
DNLED
2221
ALILD
2226
IKYST
2231
IGLAQ
2236
QWDQL
2241
YQLGL
2246
RMQHN
2251
LEQQI
2256
QAKDI
2261
KGVSE
2266
ETLKE
2271
FSTIY
2276
KHFDE
2281
NLTGR
2286
LTHKE
2291
FRSCL
2296
RGLNY
2301
YLPMV
2306
EEDEH
2311
EPKFE
2316
KFLDA
2321
VDPGR
2326
KGYVS
2331
LEDYT
2336
AFLID
2341
KESEN
2346
IKSSD
2351
EIENA
2356
FQALA
2361
EGKSY
2366
ITKED
2371
MKQAL
2376
TPEQV
2381
SFCAT
2386
HMQQY
2391
MDPRG
2396
RSHLS
2401
GYDYV
2406
GFTNS
2411
YFGN
2416
Mutation Information
DNA mutation:
c.C3193T
Peptide Range:
1053 ~ 1077
Mut AA position:
1065 (13 in Wild Type peptide)
Alignment
Wild Type:
"ITQRQEQIENQYRSLLDRAEERRRR
||||||||||||.||||||||||||
Mutant:
ITQRQEQIENQYCSLLDRAEERRRR"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) SPTA1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
ITQRQEQIENQYCSLLDRAEERRRR
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT