Immunogenicity 11601
Sample ID
3309
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TLR8
Transcript ID
uc004cvd.3
HLA INFO
A*11:01
TCR INFO
No TCR info found!
Full length protein sequence (1059 aa)
MKESS
1
LQNSS
6
CSLGK
11
ETKKE
16
NMFLQ
21
SSMLT
26
CIFLL
31
ISGSC
36
ELCAE
41
ENFSR
46
SYPCD
51
EKKQN
56
DSVIA
61
ECSNR
66
RLQEV
71
PQTVG
76
KYVTE
81
LDLSD
86
NFITH
91
ITNES
96
FQGLQ
101
NLTKI
106
NLNHN
111
PNVQH
116
QNGNP
121
GIQSN
126
GLNIT
131
DGAFL
136
NLKNL
141
RELLL
146
EDNQL
151
PQIPS
156
GLPES
161
LTELS
166
LIQNN
171
IYNIT
176
KEGIS
181
RLINL
186
KNLYL
191
AWNCY
196
FNKVC
201
EKTNI
206
EDGVF
211
ETLTN
216
LELLS
221
LSFNS
226
LSHVP
231
PKLPS
236
SLRKL
241
FLSNT
246
QIKYI
251
SEEDF
256
KGLIN
261
LTLLD
266
LSGNC
271
PRCFN
276
APFPC
281
VPCDG
286
GASIN
291
IDRFA
296
FQNLT
301
QLRYL
306
NLSST
311
SLRKI
316
NAAWF
321
KNMPH
326
LKVLD
331
LEFNY
336
LVGEI
341
ASGAF
346
LTMLP
351
RLEIL
356
DLSFN
361
YIKGS
366
YPQHI
371
NISRN
376
FSKLL
381
SLRAL
386
HLRGY
391
VFQEL
396
REDDF
401
QPLMQ
406
LPNLS
411
TINLG
416
INFIK
421
QIDFK
426
LFQNF
431
SNLEI
436
IYLSE
441
NRISP
446
LVKDT
451
RQSYA
456
NSSSF
461
QRHIR
466
KRRST
471
DFEFD
476
PHSNF
481
YHFTR
486
PLIKP
491
QCAAY
496
GKALD
501
LSLNS
506
IFFIG
511
PNQFE
516
NLPDI
521
ACLNL
526
SANSN
531
AQVLS
536
GTEFS
541
AIPHV
546
KYLDL
551
TNNRL
556
DFDNA
561
SALTE
566
LSDLE
571
VLDLS
576
YNSHY
581
FRIAG
586
VTHHL
591
EFIQN
596
FTNLK
601
VLNLS
606
HNNIY
611
TLTDK
616
YNLES
621
KSLVE
626
LVFSG
631
NRLDI
636
LWNDD
641
DNRYI
646
SIFKG
651
LKNLT
656
RLDLS
661
LNRLK
666
HIPNE
671
AFLNL
676
PASLT
681
ELHIN
686
DNMLK
691
FFNWT
696
LLQQF
701
PRLEL
706
LDLRG
711
NKLLF
716
LTDSL
721
SDFTS
726
SLRTL
731
LLSHN
736
RISHL
741
PSGFL
746
SEVSS
751
LKHLD
756
LSSNL
761
LKTIN
766
KSALE
771
TKTTT
776
KLSML
781
ELHGN
786
PFECT
791
CDIGD
796
FRRWM
801
DEHLN
806
VKIPR
811
LVDVI
816
CASPG
821
DQRGK
826
SIVSL
831
ELTTC
836
VSDVT
841
AVILF
846
FFTFF
851
ITTMV
856
MLAAL
861
AHHLF
866
YWDVW
871
FIYNV
876
CLAKV
881
KGYRS
886
LSTSQ
891
TFYDA
896
YISYD
901
TKDAS
906
VTDWV
911
INELR
916
YHLEE
921
SRDKN
926
VLLCL
931
EERDW
936
DPGLA
941
IIDNL
946
MQSIN
951
QSKKT
956
VFVLT
961
KKYAK
966
SWNFK
971
TAFYL
976
ALQRL
981
MDENM
986
DVIIF
991
ILLEP
996
VLQHS
1001
QYLRL
1006
RQRIC
1011
KSSIL
1016
QWPDN
1021
PKAEG
1026
LFWQT
1031
LRNVV
1036
LTEND
1041
SRYNN
1046
MYVDS
1051
IKQY
1056
Mutation Information
DNA mutation:
c.1757T>C
Peptide Range:
579 ~ 587
Mut AA position:
586 (8 in Wild Type peptide)
Alignment
Wild Type:
"LSYNSHYFR
|||||||.|
Mutant:
LSYNSHYSR"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) TLR8
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
COS7
Assay
IFNg ELISPOT assay