Immunogenicity 11606
Sample ID
2098
Response
Negative
Tumor Type
Melanoma
Gene Symbol
A2ML1
Transcript ID
uc001quz.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1454 aa)
MWAQL
1
LLGML
6
ALSPA
11
IAEEL
16
PNYLV
21
TLPAR
26
LNFPS
31
VQKVC
36
LDLSP
41
GYSDV
46
KFTVT
51
LETKD
56
KTQKL
61
LEYSG
66
LKKRH
71
LHCIS
76
FLVPP
81
PAGGT
86
EEVAT
91
IRVSG
96
VGNNI
101
SFEEK
106
KKVLI
111
QRQGN
116
GTFVQ
121
TDKPL
126
YTPGQ
131
QVYFR
136
IVTMD
141
SNFVP
146
VNDKY
151
SMVEL
156
QDPNS
161
NRIAQ
166
WLEVV
171
PEQGI
176
VDLSF
181
QLAPE
186
AMLGT
191
YTVAV
196
AEGKT
201
FGTFS
206
VEEYV
211
LPKFK
216
VEVVE
221
PKELS
226
TVQES
231
FLVKI
236
CCRYT
241
YGKPM
246
LGAVQ
251
VSVCQ
256
KANTY
261
WYREV
266
EREQL
271
PDKCR
276
NLSGQ
281
TDKTG
286
CFSAP
291
VDMAT
296
FDLIG
301
YAYSH
306
QINIV
311
ATVVE
316
EGTGV
321
EANAT
326
QNIYI
331
SPQMG
336
SMTFE
341
DTSNF
346
YHPNF
351
PFSGK
356
IRVRG
361
HDDSF
366
LKNHL
371
VFLVI
376
YGTNG
381
TFNQT
386
LVTDN
391
NGLAP
396
FTLET
401
SGWNG
406
TDVSL
411
EGKFQ
416
MEDLV
421
YNPEQ
426
VPRYY
431
QNAYL
436
HLRPF
441
YSTTR
446
SFLGI
451
HRLNG
456
PLKCG
461
QPQEV
466
LVDYY
471
IDPAD
476
ASPDQ
481
EISFS
486
YYLIG
491
KGSLV
496
MEGQK
501
HLNSK
506
KKGLK
511
ASFSL
516
SLTFT
521
SRLAP
526
DPSLV
531
IYAIF
536
PSGGV
541
VADKI
546
QFSVE
551
MCFDN
556
QVSLG
561
FSPSQ
566
QLPGA
571
EVELQ
576
LQAAP
581
GSLCA
586
LRAVD
591
ESVLL
596
LRPDR
601
ELSNR
606
SVYGM
611
FPFWY
616
GHYPY
621
QVAEY
626
DQCPV
631
SGPWD
636
FPQPL
641
IDPMP
646
QGHSS
651
QRSII
656
WRPSF
661
SEGTD
666
LFSFF
671
RDVGL
676
KILSN
681
AKIKK
686
PVDCS
691
HRSPE
696
YSTAM
701
GAGGG
706
HPEAF
711
ESSTP
716
LHQAE
721
DSQVR
726
QYFPE
731
TWLWD
736
LFPIG
741
NSGKE
746
AVHVT
751
VPDAI
756
TEWKA
761
MSFCT
766
SQSRG
771
FGLSP
776
TVGLT
781
AFKPF
786
FVDLT
791
LPYSV
796
VRGES
801
FRLTA
806
TIFNY
811
LKDCI
816
RVQTD
821
LAKSH
826
EYQLE
831
SWADS
836
QTSSC
841
LCADD
846
AKTHH
851
WNITA
856
VKLGH
861
INFTI
866
STKIL
871
DSNEP
876
CGGQK
881
GFVPQ
886
KGRSD
891
TLIKP
896
VLVKP
901
EGVLV
906
EKTHS
911
SLLCP
916
KGKVA
921
SESVS
926
LELPV
931
DIVPD
936
STKAY
941
VTVLG
946
DIMGT
951
ALQNL
956
DGLVQ
961
MPSGC
966
GEQNM
971
VLFAP
976
IIYVL
981
QYLEK
986
AGLLT
991
EEIRS
996
RAVGF
1001
LEIGY
1006
QKELM
1011
YKHSN
1016
GSYSA
1021
FGERD
1026
GNGNT
1031
WLTAF
1036
VTKCF
1041
GQAQK
1046
FIFID
1051
PKNIQ
1056
DALKW
1061
MAGNQ
1066
LPSGC
1071
YANVG
1076
NLLHT
1081
AMKGG
1086
VDDEV
1091
SLTAY
1096
VTAAL
1101
LEMGK
1106
DVDDP
1111
MVSQG
1116
LRCLK
1121
NSATS
1126
TTNLY
1131
TQALL
1136
AYIFS
1141
LAGEM
1146
DIRNI
1151
LLKQL
1156
DQQAI
1161
ISGES
1166
IYWSQ
1171
KPTPS
1176
SNASP
1181
WSEPA
1186
AVDVE
1191
LTAYA
1196
LLAQL
1201
TKPSL
1206
TQKEI
1211
AKATS
1216
IVAWL
1221
AKQHN
1226
AYGGF
1231
SSTQD
1236
TVVAL
1241
QALAK
1246
YATTA
1251
YMPSE
1256
EINLV
1261
VKSTE
1266
NFQRT
1271
FNIQS
1276
VNRLV
1281
FQQDT
1286
LPNVP
1291
GMYTL
1296
EASGQ
1301
GCVYV
1306
QTVLR
1311
YNILP
1316
PTNMK
1321
TFSLS
1326
VEIGK
1331
ARCEQ
1336
PTSPR
1341
SLTLT
1346
IHTSY
1351
VGSRS
1356
SSNMA
1361
IVEVK
1366
MLSGF
1371
SPMEG
1376
TNQLL
1381
LQQPL
1386
VKKVE
1391
FGTDT
1396
LNIYL
1401
DELIK
1406
NTQTY
1411
TFTIS
1416
QSVLV
1421
TNLKP
1426
ATIKV
1431
YDYYL
1436
PDEQA
1441
TIQYS
1446
DPCE
1451
Mutation Information
DNA mutation:
c.4229A>G
Peptide Range:
1404 ~ 1412
Mut AA position:
1410 (7 in Wild Type peptide)
Alignment
Wild Type:
"YLDELIKNT
||||||.||
Mutant:
YLDELIRNT"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) A2ML1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
T2
Assay
IFNg ELISPOT assay