Immunogenicity 11608
Sample ID
2098
Response
Negative
Tumor Type
Melanoma
Gene Symbol
UNC13A
Transcript ID
uc021uqk.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1702 aa)
MSLLC
1
VGVKK
6
AKFDG
11
AQEKF
16
NTYVT
21
LKVQN
26
VKSTT
31
IAVRG
36
SQPSW
41
EQDFM
46
FEINR
51
LDLGL
56
TVEVW
61
NKGLI
66
WDTMV
71
GTVWI
76
PLRTI
81
RQSNE
86
EGPGE
91
WLTLD
96
SQVIM
101
ADSEI
106
CGTKD
111
PTFHR
116
ILLDT
121
RFELP
126
LDIPE
131
EEARY
136
WAKKL
141
EQLNA
146
MRDQD
151
EYSFQ
156
DEQDK
161
PLPVP
166
SNQCC
171
NWNYF
176
GWGEQ
181
HNDDP
186
DSAVD
191
DRDSD
196
YRSET
201
SNSIP
206
PPYYT
211
TSQPN
216
ASVHQ
221
YSVRP
226
PPLGS
231
RESYS
236
DSMHS
241
YEEFS
246
EPQAL
251
SPTGS
256
SRYAS
261
SGELS
266
QGSSQ
271
LSEDF
276
DPDEH
281
SLQGS
286
DMEDE
291
RDRDS
296
YHSCH
301
SSVSY
306
HKDSP
311
RWDQD
316
EEELE
321
EDLED
326
FLEEE
331
ELPED
336
EEELE
341
EEEEE
346
VPDDL
351
GSYAQ
356
REDVA
361
VAEPK
366
DFKRI
371
SLPPA
376
APGKE
381
DKAPV
386
APTEA
391
PDMAK
396
VAPKP
401
ATPDK
406
VPAAE
411
QIPEA
416
EPPKD
421
EESFR
426
PREDE
431
EGQEG
436
QDSMS
441
RAKAN
446
WLRAF
451
NKVRM
456
QLQEA
461
RGEGE
466
MSKSL
471
WFKGG
476
PGGGL
481
IIIDS
486
MPDIR
491
KRKPI
496
PLVSD
501
LAMSL
506
VQSRK
511
AGITS
516
ALASS
521
TLNNE
526
ELKNH
531
VYKKT
536
LQALI
541
YPISC
546
TTPHN
551
FEVWT
556
ATTPT
561
YCYEC
566
EGLLW
571
GIARQ
576
GMRCT
581
ECGVK
586
CHEKC
591
QDLLN
596
ADCLQ
601
RAAEK
606
SSKHG
611
AEDRT
616
QNIIM
621
VLKDR
626
MKIRE
631
RNKPE
636
IFELI
641
QEIFA
646
VTKTA
651
HTQQM
656
KAVKQ
661
SVLDG
666
TSKWS
671
AKISI
676
TVVCA
681
QGLQA
686
KDKTG
691
SSDPY
696
VTVQV
701
GKTKK
706
RTKTI
711
YGNLN
716
PVWEE
721
NFHFE
726
CHNSS
731
DRIKV
736
RVWDE
741
DDDIK
746
SRVKQ
751
RFKRE
756
SDDFL
761
GQTII
766
EVRTL
771
SGEMD
776
VWYNL
781
DKRTD
786
KSAVS
791
GAIRL
796
HISVE
801
IKGEE
806
KVAPY
811
HVQYT
816
CLHEN
821
LFHFV
826
TDVQN
831
NGVVK
836
IPDAK
841
GDDAW
846
KVYYD
851
ETAQE
856
IVDEF
861
AMRYG
866
VESIY
871
QAMTH
876
FACLS
881
SKYMC
886
PGVPA
891
VMSTL
896
LANIN
901
AYYAH
906
TTAST
911
NVSAS
916
DRFAA
921
SNFGK
926
ERFVK
931
LLDQL
936
HNSLR
941
IDLSM
946
YRNNF
951
PASSP
956
ERLQD
961
LKSTV
966
DLLTS
971
ITFFR
976
MKVQE
981
LQSPP
986
RASQV
991
VKDCV
996
KACLN
1001
STYEY
1006
IFNNC
1011
HELYS
1016
REYQT
1021
DPAKK
1026
GEVLP
1031
EEQGP
1036
SIKNL
1041
DFWSK
1046
LITLI
1051
VSIIE
1056
EDKNS
1061
YTPCL
1066
NQFPQ
1071
ELNVG
1076
KISAE
1081
VMWNL
1086
FAQDM
1091
KYAME
1096
EHDKH
1101
RLCKS
1106
ADYMN
1111
LHFKV
1116
KWLYN
1121
EYVTE
1126
LPAFK
1131
DRVPE
1136
YPAWF
1141
EPFVI
1146
QWLDE
1151
NEEVS
1156
RDFLH
1161
GALER
1166
DKKDG
1171
FQQTS
1176
EHALF
1181
SCSVV
1186
DVFSQ
1191
LNQSF
1196
EIIKK
1201
LECPD
1206
PQIVG
1211
HYMRR
1216
FAKTI
1221
SNVLL
1226
QYADI
1231
ISKDF
1236
ASYCS
1241
KEKEK
1246
PCILM
1251
NNTQQ
1256
LRVQL
1261
EKMFE
1266
AMGGK
1271
ELDAE
1276
ASDIL
1281
KELQV
1286
KLNNV
1291
LDELS
1296
RVFAT
1301
SFQPH
1306
IEECV
1311
KQMGD
1316
ILSQV
1321
KGTGN
1326
VPASA
1331
CSSVA
1336
QDADN
1341
VLQPI
1346
MDLLD
1351
SNLTL
1356
FAKIC
1361
EKTVL
1366
KRVLK
1371
ELWKL
1376
VMNTM
1381
EKTIV
1386
LPPLT
1391
DQTMI
1396
GNLLR
1401
KHGKG
1406
LEKGR
1411
VKLPS
1416
HSDGT
1421
QMIFN
1426
AAKEL
1431
GQLSK
1436
LKDHM
1441
VREEA
1446
KSLTP
1451
KQCAV
1456
VELAL
1461
DTIKQ
1466
YFHAG
1471
GVGLK
1476
KTFLE
1481
KSPDL
1486
QSLRY
1491
ALSLY
1496
TQATD
1501
LLIKT
1506
FVQTQ
1511
SAQGL
1516
GVEDP
1521
VGEVS
1526
VHVEL
1531
FTHPG
1536
TGEHK
1541
VTVKV
1546
VAAND
1551
LKWQT
1556
SGIFR
1561
PFIEV
1566
NIIGP
1571
QLSDK
1576
KRKFA
1581
TKSKN
1586
NSWAP
1591
KYNES
1596
FQFTL
1601
SADAG
1606
PECYE
1611
LQVCV
1616
KDYCF
1621
AREDR
1626
TVGLA
1631
VLQLR
1636
ELAQR
1641
GSAAC
1646
WLPLG
1651
RRIHM
1656
DDTGL
1661
TVLRI
1666
LSQRS
1671
NDEVA
1676
KEFVK
1681
LKSDT
1686
RSAEE
1691
GGAAP
1696
AP
1701
Mutation Information
DNA mutation:
c.3581G>A
Peptide Range:
1194 ~ 1202
Mut AA position:
1194 (1 in Wild Type peptide)
Alignment
Wild Type:
"SQLNQSFEI
.||||||||
Mutant:
FQLNQSFEI"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) UNC13A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
T2
Assay
IFNg ELISPOT assay