Immunogenicity 1161

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
PMS1
Transcript ID
ENST00000424307
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (711 aa)
MKQLP
1
AATVR
6
LLSSS
11
QIITS
16
VVSVV
21
KELIE
26
NSLDA
31
GATSV
36
DVKLV
41
LITTR
46
TAADN
51
FSTQY
56
VLDGS
61
GHILS
66
QKPSH
71
LGQGT
76
TVTAL
81
RLFKN
86
LPVRK
91
QFYST
96
AKKCK
101
DEIKK
106
IQDLL
111
MSFGI
116
LKPDL
121
RIVFV
126
HNKAV
131
IWQKS
136
RVSDH
141
KMALM
146
SVLGT
151
AVMNN
156
MESFQ
161
YHSEE
166
SQIYL
171
SGFLP
176
KCDAD
181
HSFTS
186
LSTPE
191
RSFIF
196
INSRP
201
VHQKD
206
ILKLI
211
RHHYN
216
LKCLK
221
ESTRL
226
YPVFF
231
LKIDV
236
PTADV
241
DVNLT
246
PDKSQ
251
VLLQN
256
KESVL
261
IALEN
266
LMTTC
271
YGPLP
276
STNSY
281
ENNKT
286
DVSAA
291
DIVLS
296
KTAET
301
DVLFN
306
KVESS
311
GKNYS
316
NVDTS
321
VIPFQ
326
NDMHN
331
DESGK
336
NTDDC
341
LNHQI
346
SIGDF
351
GYGHC
356
SSEIS
361
NIDKN
366
TKNAF
371
QDISM
376
SNVSW
381
ENSQT
386
EYSKT
391
CFISS
396
VKHTQ
401
SENGN
406
KDHID
411
ESGEN
416
EEEAG
421
LENSS
426
EISAD
431
EWSRG
436
NILKN
441
SVGEN
446
IEPVK
451
ILVPE
456
KSLPC
461
KVSNN
466
NYPIP
471
EQMNL
476
NEDSC
481
NKKSN
486
VIDNK
491
SGKVT
496
AYDLL
501
SNRVI
506
KKPMS
511
ASALF
516
VQDHR
521
PQFLI
526
ENPKT
531
SLEDA
536
TLQIE
541
ELWKT
546
LSEEE
551
KLKYE
556
EKATK
561
DLERY
566
NSQMK
571
RAIEQ
576
ESQMS
581
LKDGR
586
KKIKP
591
TSAWN
596
LAQKH
601
KLKTS
606
LSNQP
611
KLDEL
616
LQSQI
621
EKRRS
626
QNIKM
631
VQIPF
636
SMKNL
641
KINFK
646
KQNKV
651
DLEEK
656
DEPCL
661
IHNLR
666
FPDAW
671
LMTSK
676
TEVML
681
LNPYR
686
VEEAL
691
LFKRL
696
LENHK
701
LPAEP
706
L
711
Mutation Information
DNA mutation:
None
Peptide Range:
154 ~ 178
Mut AA position:
166 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTAVMNNMESFQYHSEESQIYLSGF
||||||||||||.||||||||||||
Mutant:
GTAVMNNMESFQNHSEESQIYLSGF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PMS1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay