Immunogenicity 11630
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PLCB1
Transcript ID
uc002wna.3
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1173 aa)
MAGAQ
1
PGVHA
6
LQLKP
11
VCVSD
16
SLKKG
21
TKFVK
26
WDDDS
31
TIVTP
36
IILRT
41
DPQGF
46
FFYWT
51
DQNKE
56
TELLD
61
LSLVK
66
DARCG
71
RHAKA
76
PKDPK
81
LRELL
86
DVGNI
91
GRLEQ
96
RMITV
101
VYGPD
106
LVNIS
111
HLNLV
116
AFQEE
121
VAKEW
126
TNEVF
131
SLATN
136
LLAQN
141
MSRDA
146
FLEKA
151
YTKLK
156
LQVTP
161
EGRIP
166
LKNIY
171
RLFSA
176
DRKRV
181
ETALE
186
ACSLP
191
SSRND
196
SIPQE
201
DFTPE
206
VYRVF
211
LNNLC
216
PRPEI
221
DNIFS
226
EFGAK
231
SKPYL
236
TVDQM
241
MDFIN
246
LKQRD
251
PRLNE
256
ILYPP
261
LKQEQ
266
VQVLI
271
EKYEP
276
NNSLA
281
RKGQI
286
SVDGF
291
MRYLS
296
GEENG
301
VVSPE
306
KLDLN
311
EDMSQ
316
PLSHY
321
FINSS
326
HNTYL
331
TAGQL
336
AGNSS
341
VEMYR
346
QVLLS
351
GCRCV
356
ELDCW
361
KGRTA
366
EEEPV
371
ITHGF
376
TMTTE
381
ISFKE
386
VIEAI
391
AECAF
396
KTSPF
401
PILLS
406
FENHV
411
DSPKQ
416
QAKMA
421
EYCRL
426
IFGDA
431
LLMEP
436
LEKYP
441
LESGV
446
PLPSP
451
MDLMY
456
KILVK
461
NKKKS
466
HKSSE
471
GSGKK
476
KLSEQ
481
ASNTY
486
SDSSS
491
MFEPS
496
SPGAG
501
EADTE
506
SDDDD
511
DDDDC
516
KKSSM
521
DEGTA
526
GSEAM
531
ATEEM
536
SNLVN
541
YIQPV
546
KFESF
551
EISKK
556
RNKSF
561
EMSSF
566
VETKG
571
LEQLT
576
KSPVE
581
FVEYN
586
KMQLS
591
RIYPK
596
GTRVD
601
SSNYM
606
PQLFW
611
NAGCQ
616
MVALN
621
FQTMD
626
LAMQI
631
NMGMY
636
EYNGK
641
SGYRL
646
KPEFM
651
RRPDK
656
HFDPF
661
TEGIV
666
DGIVA
671
NTLSV
676
KIISG
681
QFLSD
686
KKVGT
691
YVEVD
696
MFGLP
701
VDTRR
706
KAFKT
711
KTSQG
716
NAVNP
721
VWEEE
726
PIVFK
731
KVVLP
736
TLACL
741
RIAVY
746
EEGGK
751
FIGHR
756
ILPVQ
761
AIRPG
766
YHYIC
771
LRNER
776
NQPLT
781
LPAVF
786
VYIEV
791
KDYVP
796
DTYAD
801
VIEAL
806
SNPIR
811
YVNLM
816
EQRAK
821
QLAAL
826
TLEDE
831
EEVKK
836
EADPG
841
ETPSE
846
APSEA
851
RTTPA
856
ENGVN
861
HTTTL
866
TPKPP
871
SQALH
876
SQPAP
881
GSVKA
886
PAKTE
891
DLIQS
896
VLTEV
901
EAQTI
906
EELKQ
911
QKSFV
916
KLQKK
921
HYKEM
926
KDLVK
931
RHHKK
936
TTDLI
941
KEHTT
946
KYNEI
951
QNDYL
956
RRRAA
961
LEKSA
966
KKDSK
971
KKSEP
976
SSPDH
981
GSSTI
986
EQDLA
991
ALDAE
996
MTQKL
1001
IDLKD
1006
KQQQQ
1011
LLNLR
1016
QEQYY
1021
SEKYQ
1026
KREHI
1031
KLLIQ
1036
KLTDV
1041
AEECQ
1046
NNQLK
1051
KLKEI
1056
CEKEK
1061
KELKK
1066
KMDKK
1071
RQEKI
1076
TEAKS
1081
KDKSQ
1086
MEEEK
1091
TEMIR
1096
SYIQE
1101
VVQYI
1106
KRLEE
1111
AQSKR
1116
QEKLV
1121
EKHKE
1126
IRQQI
1131
LDEKP
1136
KGEGS
1141
SSFLS
1146
ETCHE
1151
DPSVS
1156
PNFTP
1161
PNPQA
1166
LKW
1171
Mutation Information
DNA mutation:
c.2062C>T
Peptide Range:
688 ~ 697
Mut AA position:
688 (1 in Wild Type peptide)
Alignment
Wild Type:
"LSDKKVGTYV
.|||||||||
Mutant:
FSDKKVGTYV"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) PLCB1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay