Immunogenicity 11635
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RHOT2
Transcript ID
uc002ciq.1
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (511 aa)
MGGPR
1
RGPVG
6
NKSDL
11
RSGSS
16
MEAVL
21
PIMSQ
26
FPEIE
31
TCVEC
36
SAKNL
41
RNISE
46
LFYYA
51
QKAVL
56
HPTAP
61
LYDPE
66
AKQLR
71
PACAQ
76
ALTRI
81
FRLSD
86
QDLDQ
91
ALSDE
96
ELNAF
101
QKSCF
106
GHPLA
111
PQALE
116
DVKTV
121
VCRNV
126
AGGVR
131
EDRLT
136
LDGFL
141
FLNTL
146
FIQRG
151
RHETT
156
WTILR
161
RFGYS
166
DALEL
171
TADYL
176
SPLIH
181
VPPGC
186
STELN
191
HLGYQ
196
FVQRV
201
FEKHD
206
QDRDG
211
ALSPV
216
ELQSL
221
FSVFP
226
AAPWG
231
PELPR
236
TVRTE
241
AGRLP
246
LHGYL
251
CQWTL
256
VTYLD
261
VRSCL
266
GHLGY
271
LGYPT
276
LCEQD
281
QAHAI
286
TVTRE
291
KRLDQ
296
EKGQT
301
QRSVL
306
LCKVV
311
GARGV
316
GKSAF
321
LQAFL
326
GRGLG
331
HQDTR
336
EQPPG
341
YAIDT
346
VQVNG
351
QEKYL
356
ILCEV
361
GTDGL
366
LATSL
371
DATCD
376
VACLM
381
FDGSD
386
PKSFA
391
HCASV
396
YKHHY
401
MDGQT
406
PCLFV
411
SSKAD
416
LPEGV
421
AVSGP
426
SPAEF
431
CRKHR
436
LPAPV
441
PFSCA
446
GPAEP
451
STTIF
456
TQLAT
461
MAAFP
466
HLVHA
471
ELHPS
476
SFWLR
481
GLLGV
486
VGAAV
491
AAVLS
496
FSLYR
501
VLVKS
506
Q
511
Mutation Information
DNA mutation:
c.799C>T
Peptide Range:
267 ~ 275
Mut AA position:
267 (1 in Wild Type peptide)
Alignment
Wild Type:
"RSCLGHLGY
.||||||||
Mutant:
WSCLGHLGY"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) RHOT2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay