Immunogenicity 11638

summary
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DOCK3
Transcript ID
uc011bds.2
HLA INFO
A*26:01
TCR INFO

No TCR info found!

T cell Tumor cell A*26:01
sequence
Full length protein sequence (2030 aa)
MWTPT
1
EEEKY
6
GVVIC
11
SFRGS
16
VPQGL
21
VLEIG
26
ETVQI
31
LEKCE
36
GWYRG
41
VSTKK
46
PNVKG
51
IFPAN
56
YIHLK
61
KAIVS
66
NRGQY
71
ETVVP
76
LEDSI
81
VTEVT
86
ATLQE
91
WASLW
96
KQLYV
101
KHKVD
106
LFYKL
111
RHVMN
116
ELIDL
121
RRQLL
126
SGHLT
131
QDQVR
136
EVKRH
141
ITVRL
146
DWGNE
151
HLGLD
156
LVPRK
161
DFEVV
166
DSDQI
171
SVSDL
176
YKMHL
181
SSRQS
186
VQQST
191
SQVDT
196
MRPRH
201
GETCR
206
MPVPH
211
HFFLS
216
LKSFT
221
YNTIG
226
EDTDV
231
FFSLY
236
DMREG
241
KQISE
246
RFLVR
251
LNKNG
256
GPRNP
261
EKIER
266
MCALF
271
TDLSS
276
KDMKR
281
DLYIV
286
AHVIR
291
IGRML
296
LNDSK
301
KGPPH
306
LHYRR
311
PYGCA
316
VLSIL
321
DVLQS
326
LTEVK
331
EEKDF
336
VLKVY
341
TCNNE
346
SEWSQ
351
IHENI
356
IRKSS
361
AKYSA
366
PSASH
371
GLIIS
376
LQLLR
381
GDMEQ
386
IRREN
391
PMIFN
396
RGLAI
401
TRKLG
406
FPDVI
411
MPGDI
416
RNDLY
421
LTLEK
426
GDFER
431
GGKSV
436
QKNIE
441
VTMYV
446
LYADG
451
EILKD
456
CISLG
461
SGEPN
466
RSSYH
471
SFVLY
476
HSNSP
481
RWGEI
486
IKLPI
491
PIDRF
496
RGSHL
501
RFEFR
506
HCSTK
511
DKGEK
516
KLFGF
521
AFSTL
526
MRDDG
531
TTLSD
536
DIHEL
541
YVYKC
546
DENST
551
FNNHA
556
LYLGL
561
PCCKE
566
DYNGC
571
PNIPS
576
SLIFQ
581
RSTKE
586
SFFIS
591
TQLSS
596
TKLTQ
601
NVDLL
606
ALLKW
611
KAFPD
616
RIMDV
621
LGRLR
626
HVSGE
631
EIVKF
636
LQDIL
641
DTLFV
646
ILDDN
651
TEKYG
656
LLVFQ
661
SLVFI
666
INLLR
671
DIKYF
676
HFRPV
681
MDTYI
686
QKHFA
691
GALAY
696
KELIR
701
CLKWY
706
MDCSA
711
ELIRQ
716
DHIQE
721
AMRAL
726
EYLFK
731
FIVQS
736
RILYS
741
RATCG
746
MEEEQ
751
FRSSI
756
QELFQ
761
SIRFV
766
LSLDS
771
RNSET
776
LLFTQ
781
AALLN
786
SFPTI
791
FDELL
796
QMFTV
801
QEVAE
806
FVRGT
811
LGSMP
816
STVHI
821
GQSMD
826
VVKLQ
831
SIART
836
VDSRL
841
FSFSE
846
SRRIL
851
LPVVL
856
HHIHL
861
HLRQQ
866
KELLI
871
CSGIL
876
GSIFS
881
IVKTS
886
SLEAD
891
VMEEV
896
EMMVE
901
SLLDV
906
LLQTL
911
LTIMS
916
KSHAQ
921
EAVRG
926
QRCPQ
931
CTAEI
936
TGEYV
941
SCLLS
946
LLRQM
951
CDTHF
956
QHLLD
961
NFQSK
966
DELKE
971
FLLKI
976
FCVFR
981
NLMKM
986
SVFPR
991
DWMVM
996
RLLTS
1001
NIIVT
1006
TVQYL
1011
SSALH
1016
KNFTE
1021
TDFDF
1026
KVWNS
1031
YFSLA
1036
VLFIN
1041
QPSLQ
1046
LEIIT
1051
SAKRK
1056
KILDK
1061
YGDMR
1066
VMMAY
1071
ELFSM
1076
WQNLG
1081
EHKIH
1086
FIPGM
1091
IGPFL
1096
GVTLV
1101
PQPEV
1106
RNIMI
1111
PIFHD
1116
MMDWE
1121
QRKNG
1126
NFKQV
1131
EAELI
1136
DKLDS
1141
MVSEG
1146
KGDES
1151
YRELF
1156
SLLTQ
1161
LFGPY
1166
PSLLE
1171
KVEQE
1176
TWRET
1181
GISFV
1186
TSVTR
1191
LMERL
1196
LDYRD
1201
CMKGE
1206
ETENK
1211
KIGCT
1216
VNLMN
1221
FYKSE
1226
INKEE
1231
MYIRY
1236
IHKLC
1241
DMHLQ
1246
AENYT
1251
EAAFT
1256
LLLYC
1261
ELLQW
1266
EDRPL
1271
REFLH
1276
YPSQT
1281
EWQRK
1286
EGLCR
1291
KIIHY
1296
FNKGK
1301
SWEFG
1306
IPLCR
1311
ELACQ
1316
YESLY
1321
DYQSL
1326
SWIRK
1331
MEASY
1336
YDNIM
1341
EQQRL
1346
EPEFF
1351
RVGFY
1356
GRKFP
1361
FFLRN
1366
KEYVC
1371
RGHDY
1376
ERLEA
1381
FQQRM
1386
LSEFP
1391
QAVAM
1396
QHPNH
1401
PDDAI
1406
LQCDA
1411
QYLQI
1416
YAVTP
1421
IPDYV
1426
DVLQM
1431
DRVPD
1436
RVKSF
1441
YRVNN
1446
VRKFR
1451
YDRPF
1456
HKGPK
1461
DKENE
1466
FKSLW
1471
IERTT
1476
LTLTH
1481
SLPGI
1486
SRWFE
1491
VERRE
1496
LVEVS
1501
PLENA
1506
IQVVE
1511
NKNQE
1516
LRSLI
1521
SQYQH
1526
KQVHG
1531
NINLL
1536
SMCLN
1541
GVIDA
1546
AVNGG
1551
IARYQ
1556
EAFFD
1561
KDYIN
1566
KHPGD
1571
AEKIT
1576
QLKEL
1581
MQEQV
1586
HVLGV
1591
GLAVH
1596
EKFVH
1601
PEMRP
1606
LHKKL
1611
IDQFQ
1616
MMRAS
1621
LYHEF
1626
PGLDK
1631
LSPAC
1636
SGTST
1641
PRGNV
1646
LASHS
1651
PMSPE
1656
SIKMT
1661
HRHSP
1666
MNLMG
1671
TGRHS
1676
SSSLS
1681
SHASS
1686
EAGNM
1691
VMLGD
1696
GSMGD
1701
APEDL
1706
YHHMQ
1711
LAYPN
1716
PRYQG
1721
SVTNV
1726
SVLSS
1731
SQASP
1736
SSSSL
1741
SSTHS
1746
APSQM
1751
ITSAP
1756
SSARG
1761
SPSLP
1766
DKYRH
1771
AREMM
1776
LLLPT
1781
YRDRP
1786
SSAMY
1791
PAAIL
1796
ENGQP
1801
PNFQR
1806
ALFQQ
1811
VVGAC
1816
KPCSD
1821
PNLSV
1826
AEKGH
1831
YSLHF
1836
DAFHH
1841
PLGDT
1846
PPALP
1851
ARTLR
1856
KSPLH
1861
PIPAS
1866
PTSPQ
1871
SGLDG
1876
SNSTL
1881
SGSAS
1886
SGVSS
1891
LSESN
1896
FGHSS
1901
EAPPR
1906
TDTMD
1911
SMPSQ
1916
AWNAD
1921
EDLEP
1926
PYLPV
1931
HYSLS
1936
ESAVL
1941
DSIKA
1946
QPCRS
1951
HSAPG
1956
CVIPQ
1961
DPMDP
1966
PALPP
1971
KPYHP
1976
RLPAL
1981
EHDEG
1986
VLLRE
1991
ETERP
1996
RGLHR
2001
KAPLP
2006
PGSAK
2011
EEQAR
2016
MAWEH
2021
GRGEQ
2026
Mutation Information
DNA mutation:
c.3506C>T
Peptide Range:
1180 ~ 1188
Mut AA position:
1169 (9 in Wild Type peptide)
Alignment
Wild Type:
"ETWRETGIS
||||||||.
Mutant:
ETWRETGIF"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay