Immunogenicity 11665
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SLIT2
Transcript ID
ENST00000273739
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1542 aa)
MRGVG
1
WQMLS
6
LSLGL
11
VLAIL
16
NKVAP
21
QACPA
26
QCSCS
31
GSTVD
36
CHGLA
41
LRSVP
46
RNIPR
51
NTERL
56
DLNGN
61
NITRI
66
TKTDF
71
AGLRH
76
LRVLQ
81
LMENK
86
ISTIE
91
RGAFQ
96
DLKEL
101
ERLRL
106
NRNHL
111
QLFPE
116
LLFLG
121
TAKLY
126
RLDLS
131
ENQIQ
136
AIPRK
141
AFRGA
146
VDIKN
151
LQLDY
156
NQISC
161
IEDGA
166
FRALR
171
DLEVL
176
TLNNN
181
NITRL
186
SVASF
191
NHMPK
196
LRTFR
201
LHSNN
206
LYCDC
211
HLAWL
216
SDWLR
221
QRPRV
226
GLYTQ
231
CMGPS
236
HLRGH
241
NVAEV
246
QKREF
251
VCSDE
256
EEGHQ
261
SFMAP
266
SCSVL
271
HCPAA
276
CTCSN
281
NIVDC
286
RGKGL
291
TEIPT
296
NLPET
301
ITEIR
306
LEQNT
311
IKVIP
316
PGAFS
321
PYKKL
326
RRIDL
331
SNNQI
336
SELAP
341
DAFQG
346
LRSLN
351
SLVLY
356
GNKIT
361
ELPKS
366
LFEGL
371
FSLQL
376
LLLNA
381
NKINC
386
LRVDA
391
FQDLH
396
NLNLL
401
SLYDN
406
KLQTI
411
AKGTF
416
SPLRA
421
IQTMH
426
LAQNP
431
FICDC
436
HLKWL
441
ADYLH
446
TNPIE
451
TSGAR
456
CTSPR
461
RLANK
466
RIGQI
471
KSKKF
476
RCSAK
481
EQYFI
486
PGTED
491
YRSKL
496
SGDCF
501
ADLAC
506
PEKCR
511
CEGTT
516
VDCSN
521
QKLNK
526
IPEHI
531
PQYTA
536
ELRLN
541
NNEFT
546
VLEAT
551
GIFKK
556
LPQLR
561
KINFS
566
NNKIT
571
DIEEG
576
AFEGA
581
SGVNE
586
ILLTS
591
NRLEN
596
VQHKM
601
FKGLE
606
SLKTL
611
MLRSN
616
RITCV
621
GNDSF
626
IGLSS
631
VRLLS
636
LYDNQ
641
ITTVA
646
PGAFD
651
TLHSL
656
STLNL
661
LANPF
666
NCNCY
671
LAWLG
676
EWLRK
681
KRIVT
686
GNPRC
691
QKPYF
696
LKEIP
701
IQDVA
706
IQDFT
711
CDDGN
716
DDNSC
721
SPLSR
726
CPTEC
731
TCLDT
736
VVRCS
741
NKGLK
746
VLPKG
751
IPRDV
756
TELYL
761
DGNQF
766
TLVPK
771
ELSNY
776
KHLTL
781
IDLSN
786
NRIST
791
LSNQS
796
FSNMT
801
QLLTL
806
ILSYN
811
RLRCI
816
PPRTF
821
DGLKS
826
LRLLS
831
LHGND
836
ISVVP
841
EGAFN
846
DLSAL
851
SHLAI
856
GANPL
861
YCDCN
866
MQWLS
871
DWVKS
876
EYKEP
881
GIARC
886
AGPGE
891
MADKL
896
LLTTP
901
SKKFT
906
CQGPV
911
DVNIL
916
AKCNP
921
CLSNP
926
CKNDG
931
TCNSD
936
PVDFY
941
RCTCP
946
YGFKG
951
QDCDV
956
PIHAC
961
ISNPC
966
KHGGT
971
CHLKE
976
GEEDG
981
FWCIC
986
ADGFE
991
GENCE
996
VNVDD
1001
CEDND
1006
CENNS
1011
TCVDG
1016
INNYT
1021
CLCPP
1026
EYTAA
1031
NLNEV
1036
EKGEL
1041
CEEKL
1046
DFCAQ
1051
DLNPC
1056
QHDSK
1061
CILTP
1066
KGFKC
1071
DCTPG
1076
YVGEH
1081
CDIDF
1086
DDCQD
1091
NKCKN
1096
GAHCT
1101
DAVNG
1106
YTCIC
1111
PEGYS
1116
GLFCE
1121
FSPPM
1126
VLPRT
1131
SPCDN
1136
FDCQN
1141
GAQCI
1146
VRINE
1151
PICQC
1156
LPGYQ
1161
GEKCE
1166
KLVSV
1171
NFINK
1176
ESYLQ
1181
IPSAK
1186
VRPQT
1191
NITLQ
1196
IATDE
1201
DSGIL
1206
LYKGD
1211
KDHIA
1216
VELYR
1221
GRVRA
1226
SYDTG
1231
SHPAS
1236
AIYSV
1241
ETIND
1246
GNFHI
1251
VELLA
1256
LDQSL
1261
SLSVD
1266
GGNPK
1271
IITNL
1276
SKQST
1281
LNFDS
1286
PLYVG
1291
GMPGK
1296
SNVAS
1301
LRQAP
1306
GQNGT
1311
SFHGC
1316
IRNLY
1321
INSEL
1326
QDFQK
1331
VPMQT
1336
GILPG
1341
CEPCH
1346
KKVCA
1351
HGTCQ
1356
PSSQA
1361
GFTCE
1366
CQEGW
1371
MGPLC
1376
DQRTN
1381
DPCLG
1386
NKCVH
1391
GTCLP
1396
INAFS
1401
YSCKC
1406
LEGHG
1411
GVLCD
1416
EEEDL
1421
FNPCQ
1426
AIKCK
1431
HGKCR
1436
LSGLG
1441
QPYCE
1446
CSSGY
1451
TGDSC
1456
DREIS
1461
CRGER
1466
IRDYY
1471
QKQQG
1476
YAACQ
1481
TTKKV
1486
SRLEC
1491
RGGCA
1496
GGQCC
1501
GPLRS
1506
KRRKY
1511
SFECT
1516
DGSSF
1521
VDEVE
1526
KVVKC
1531
GCTRC
1536
VS
1541
Mutation Information
DNA mutation:
None
Peptide Range:
1022 ~ 1046
Mut AA position:
1034 (13 in Wild Type peptide)
Alignment
Wild Type:
"NNYTCLCPPEYTAANLNEVEKGELC
||||||||||||.||||||||||||
Mutant:
NNYTCLCPPEYTTANLNEVEKGELC"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) ENSG00000145147
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay