Immunogenicity 1168
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
DNAH8
Transcript ID
ENST00000441566
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (4454 aa)
MMKLY
1
IDNAA
6
PDKLK
11
GLCIF
16
FVRCR
21
NDVAI
26
NVKTI
31
QEEAL
36
FTVLD
41
ASKGL
46
LNGIR
51
DMLAN
56
IFLPA
61
VLATN
66
NWGAL
71
NQSKQ
76
GESEK
81
HIFTE
86
TINRY
91
LSFLD
96
GARIS
101
IEGTV
106
KLKTI
111
DNVNF
116
SKLHT
121
FEEVT
126
AAASN
131
SETVH
136
QLEEV
141
LMVWY
146
KQIEQ
151
VLIES
156
EQMRK
161
EAGDS
166
GPLTE
171
LEHWK
176
RMSAK
181
FNYII
186
EQIKG
191
PSCKA
196
VINVL
201
NVAHS
206
KLLKN
211
WRDLD
216
ARITD
221
TANES
226
KDNVR
231
YLYTL
236
EKVCQ
241
PLYNH
246
DLVSM
251
AHGIQ
256
NLINA
261
IRMIH
266
GVSRY
271
YNTSE
276
RMTSL
281
FIKVT
286
NQMVT
291
ACKAY
296
ITDGG
301
LNHVW
306
DQETP
311
VVLKK
316
IQDCI
321
FLFKE
326
YQASF
331
HKTRK
336
LISES
341
SGEKS
346
FEVSE
351
MYIFG
356
KFEAF
361
CKRLE
366
KITEM
371
ITVVQ
376
TYSTL
381
SNSTI
386
EGIDI
391
MAIKF
396
RNIYQ
401
GVKKK
406
QYDIL
411
DPRRT
416
EFDTD
421
FLDFM
426
TKING
431
LEVQI
436
QAFMN
441
SSFGK
446
ILSSQ
451
QALQL
456
LQRFQ
461
KLNIP
466
CLGLE
471
INHTI
476
ERILQ
481
YYVAE
486
LDATK
491
KLYHS
496
QKDDP
501
PLARN
506
MPPIA
511
GKILW
516
VRQLY
521
RRISE
526
PINYF
531
FKNSD
536
ILSSP
541
DGKAV
546
IRQYN
551
KISYV
556
LVEFE
561
VVYHT
566
AWIRE
571
ISQLH
576
YALQA
581
TLFVR
586
HPETG
591
KLLVN
596
FDPKI
601
LEVVR
606
ETKCM
611
IKMKL
616
DVPEQ
621
AKRLL
626
KLESK
631
LKADK
636
LYLQG
641
LLQYY
646
DELCQ
651
EVPSV
656
FVNLM
661
TPKMK
666
KVESV
671
LRQGL
676
TVLTW
681
SSLTL
686
ESFFQ
691
EVELV
696
LDMFN
701
QLLKK
706
ISDLC
711
EMHID
716
TVLKE
721
IAKTV
726
LISLP
731
ESGAT
736
KVEDM
741
LTLNE
746
TYTKE
751
WADIL
756
NHKSK
761
HVEEA
766
VRELI
771
SIFEQ
776
IYEVK
781
YTGKV
786
GKQSE
791
QRKHV
796
VFGSE
801
TGEGE
806
NNDYE
811
ANIVN
816
EFDTH
821
DKEDE
826
FKKEC
831
KEVFA
836
FFSHQ
841
LLDSL
846
QKATR
851
LSLDT
856
MKRRI
861
FVASL
866
YGRKQ
871
SEDII
876
SFIKS
881
EVHLA
886
IPNVV
891
MIPSL
896
DDIQQ
901
AINRM
906
IQLTL
911
EVSRG
916
VAHWG
921
QQQIR
926
PIKSV
931
IPSPT
936
TTDVT
941
HQNTG
946
KLLKK
951
EERSF
956
EEAIP
961
ARKLK
966
NFYPG
971
VAEHK
976
DISKL
981
VLLLS
986
SSVNS
991
LRKAA
996
HEALQ
1001
DFQKY
1006
KTLWT
1011
EDRDV
1016
KVKEF
1021
LANNP
1026
SLTEI
1031
RSEIL
1036
HYATF
1041
EQEID
1046
ELKPI
1051
IVVGA
1056
LELHT
1061
EPMKL
1066
ALSIE
1071
AKAWK
1076
MLLCR
1081
YLNEE
1086
YKKKM
1091
SYMIA
1096
FINEY
1101
LKKLS
1106
RPIRD
1111
LDDVR
1116
FAMEA
1121
LSCIR
1126
DNEIQ
1131
MDMTL
1136
GPIEE
1141
AYAIL
1146
NRFEV
1151
EVTKE
1156
ESEAV
1161
DTLRY
1166
SFNKL
1171
QSKAV
1176
SVQED
1181
LVQVQ
1186
PKFKS
1191
NLLES
1196
VEVFR
1201
EDVIN
1206
FAEAY
1211
ELEGP
1216
MVPNI
1221
PPQEA
1226
SNRLQ
1231
IFQAS
1236
FDDLW
1241
RKFVT
1246
YSSGE
1251
QLFGL
1256
PVTDY
1261
EVLHK
1266
TRKEL
1271
NLLQK
1276
LYGLY
1281
DTVMS
1286
SISGY
1291
YEILW
1296
GDVDI
1301
EKINA
1306
ELLEF
1311
QNRCR
1316
KLPKG
1321
LKDWQ
1326
AFLDL
1331
KKRID
1336
DFSES
1341
CPLLE
1346
MMTNK
1351
AMKQR
1356
HWDRI
1361
SELTG
1366
TPFDV
1371
ESDSF
1376
CLRNI
1381
MEAPL
1386
LKHKD
1391
DIEDI
1396
CISAI
1401
KEKDI
1406
EAKLT
1411
QVIEN
1416
WTNQN
1421
LSFAA
1426
FKGKG
1431
ELLLK
1436
GTESG
1441
EIITL
1446
MEDSL
1451
MVLGS
1456
LLSNR
1461
YNAPF
1466
KKNIQ
1471
NWVYK
1476
LSTSS
1481
DIIEE
1486
WLVVQ
1491
NLWVY
1496
LEAVF
1501
VGGDI
1506
AKQLP
1511
QEAKR
1516
FQNID
1521
KSWIK
1526
IMQRA
1531
HENPN
1536
VINCC
1541
VGDET
1546
MGQLL
1551
PHLHE
1556
QLEVC
1561
QKSLT
1566
GYLEK
1571
KRLLF
1576
PRFFF
1581
VSDPV
1586
LLEIL
1591
GQASD
1596
SHTIQ
1601
PHLPA
1606
VSDNI
1611
NEVTF
1616
HAKDY
1621
DRIMA
1626
VISRE
1631
GEKIV
1636
LDNSV
1641
MAKGP
1646
VEIWL
1651
LDLLK
1656
MQMSS
1661
LHNII
1666
RSAFY
1671
QISDS
1676
GFQLL
1681
PFLSH
1686
FPAQV
1691
GLLGI
1696
QMLWT
1701
HDSEE
1706
ALRNA
1711
KDDRK
1716
IMQVT
1721
NQKFL
1726
DILNT
1731
LISQT
1736
THDLS
1741
KFDRV
1746
KFETL
1751
ITIHV
1756
HQRDI
1761
FDDLV
1766
KMHIK
1771
SPTDF
1776
EWLKQ
1781
SRFYF
1786
KEDLD
1791
QTVVS
1796
ITDVD
1801
FIYQN
1806
EFLGC
1811
TDRLV
1816
ITPLT
1821
DRCYI
1826
TLAQA
1831
LGMNM
1836
GGAPA
1841
GPAGT
1846
GKTET
1851
TKDMG
1856
RCLGK
1861
YVVVF
1866
NCSDQ
1871
MDFRG
1876
LGRIF
1881
KGLAQ
1886
SGSWG
1891
CFDEF
1896
NRIEL
1901
PVLSV
1906
AAQQI
1911
YIVLT
1916
ARKER
1921
KKQFI
1926
FSDGD
1931
CVDLN
1936
PEFGI
1941
FLTMN
1946
PGYAG
1951
RQELP
1956
ENLKI
1961
QFRTV
1966
AMMVP
1971
DRQVH
1976
YDFGL
1981
RNILS
1986
VLRTL
1991
GSQKR
1996
ARPED
2001
SELSI
2006
VMRGL
2011
RDMNL
2016
SKLVD
2021
EDEPL
2026
FLSLI
2031
NDLFP
2036
GLQLD
2041
SNTYA
2046
ELQNA
2051
VAHQV
2056
QIEGL
2061
INHPP
2066
WNLKL
2071
VQLYE
2076
TSLVR
2081
HGLMT
2086
LGPSG
2091
SGKTT
2096
VITIL
2101
MKAQT
2106
ECGRP
2111
HREMR
2116
MNPKA
2121
ITAPQ
2126
MFGRL
2131
DTATN
2136
DWTDG
2141
IFSTL
2146
WRKTL
2151
KAKKG
2156
ENIFL
2161
ILDGP
2166
VDAIW
2171
IENLN
2176
SVLDD
2181
NKTLT
2186
LANGD
2191
RIPMA
2196
PSCKL
2201
LFEVH
2206
NIENA
2211
SPATV
2216
SRMGM
2221
VYISS
2226
SALSW
2231
RPILQ
2236
AWLKK
2241
RTAQE
2246
AAVFL
2251
TLYEK
2256
VFEDT
2261
YTYMK
2266
LNLNP
2271
KMQLL
2276
ECNYI
2281
VQSLN
2286
LLEGL
2291
IPSKE
2296
EGGVS
2301
CVEHL
2306
HKLFV
2311
FGLMW
2316
SLGAL
2321
LELES
2326
REKLE
2331
AFLRQ
2336
HESKL
2341
DLPEI
2346
PKGSN
2351
QTMYE
2356
FYVTD
2361
YGDWE
2366
HWNKK
2371
LQPYY
2376
YPTDS
2381
IPEYS
2386
SILVP
2391
NVDNI
2396
RTNFL
2401
IDTIA
2406
KQHKA
2411
VLLTG
2416
EQGTA
2421
KTVMV
2426
KAYLK
2431
KYDPE
2436
VQLSK
2441
SLNFS
2446
SATEP
2451
MMFQR
2456
TIESY
2461
VDKRI
2466
GSTYG
2471
PPGGR
2476
KMTVF
2481
IDDIN
2486
MPVIN
2491
EWGDQ
2496
ITNEI
2501
VRQMM
2506
EMEGM
2511
YSLDK
2516
PGDFT
2521
TIVDV
2526
QLIAA
2531
MIHPG
2536
GGRND
2541
IPQRL
2546
KRQFT
2551
VFNCT
2556
LPSNA
2561
SIDKI
2566
FGIIG
2571
CGYFD
2576
PCRSF
2581
KPQIC
2586
EMIVN
2591
LVSVG
2596
RVLWQ
2601
WTKVK
2606
MLPTP
2611
SKFHY
2616
IFNLR
2621
DLSRI
2626
WQGML
2631
TIKAE
2636
ECASI
2641
PTLLS
2646
LFKHE
2651
CSRVI
2656
ADRFI
2661
TPEDE
2666
QWFNA
2671
HLTRA
2676
VEENI
2681
GSDAA
2686
SCILP
2691
EPYFV
2696
DFLRE
2701
MPEPT
2706
GDEPE
2711
DSVFE
2716
VPKIY
2721
ELMPS
2726
FDFLA
2731
EKLQF
2736
YQRQF
2741
NEIIR
2746
GTSLD
2751
LVFFK
2756
DAMTH
2761
LIKIS
2766
RIIRT
2771
SCGNA
2776
LLVGV
2781
GGSGK
2786
QSLSR
2791
LASFI
2796
AGYQI
2801
FQITL
2806
TRSYN
2811
VTNLT
2816
DDLKA
2821
LYKVA
2826
GADGK
2831
GITFI
2836
FTDSE
2841
IKDEA
2846
FLEYL
2851
NNLLS
2856
SGEIS
2861
NLFAR
2866
DEMDE
2871
ITQGL
2876
ISVMK
2881
RELPR
2886
HPPTF
2891
DNLYE
2896
YFISR
2901
SRKNL
2906
HVVLC
2911
FSPVG
2916
EKFRA
2921
RSLKF
2926
PGLIS
2931
GCTMD
2936
WFSRW
2941
PREAL
2946
IAVAS
2951
YFLSD
2956
YNIVC
2961
SSEIK
2966
RQVVE
2971
TMGLF
2976
HDMVS
2981
ESCES
2986
YFQRY
2991
RRRAH
2996
VTPKS
3001
YLSFI
3006
NGYKN
3011
IYAEK
3016
VKFIN
3021
EQAER
3026
MNIGL
3031
DKLME
3036
ASESV
3041
AKLSQ
3046
DLAVK
3051
EKELA
3056
VASIK
3061
ADEVL
3066
AEVTV
3071
SAQAS
3076
AKIKN
3081
EVQEV
3086
KDKAQ
3091
KIVDE
3096
IDSEK
3101
VKAES
3106
KLEAA
3111
KPALE
3116
EAEAA
3121
LNTIK
3126
PNDIA
3131
TVRKL
3136
AKPPH
3141
LIMRI
3146
MDCVL
3151
LLFQK
3156
KIDPV
3161
TMDPE
3166
KSCCK
3171
PSWGE
3176
SLKLM
3181
SATGF
3186
LWSLQ
3191
QFPKD
3196
TINEE
3201
TVELL
3206
QPYFN
3211
MDDYT
3216
FESAK
3221
KVCGN
3226
VAGLL
3231
SWTLA
3236
MAIFY
3241
GINRE
3246
VLPLK
3251
ANLAK
3256
QEGRL
3261
AVANA
3266
ELGKA
3271
QALLD
3276
EKQAE
3281
LDKVQ
3286
AKFDA
3291
AMNEK
3296
MDLLN
3301
DADTC
3306
RKKMQ
3311
AASTL
3316
IDGLS
3321
GEKIR
3326
WTQQS
3331
KEFKA
3336
QINRL
3341
VGDIL
3346
LCTGF
3351
LSYLG
3356
PFNQI
3361
FRNYL
3366
LKDQW
3371
EMELR
3376
ARKIP
3381
FTENL
3386
NLISM
3391
LVDPP
3396
TIGEW
3401
GLQGL
3406
PGDDL
3411
SIQNG
3416
IIVTK
3421
ATRYP
3426
LLIDP
3431
QTQGK
3436
TWIKS
3441
KEKEN
3446
DLQVT
3451
SLNHK
3456
YFRTH
3461
LEDSL
3466
SLGRP
3471
LLIED
3476
IHEEL
3481
DPALD
3486
NVLEK
3491
NFIKS
3496
GTTFK
3501
VKVGD
3506
KECDI
3511
MDTFK
3516
LYITT
3521
KLPNP
3526
AFTPE
3531
INAKT
3536
SVIDF
3541
TVTMK
3546
GLENQ
3551
LLRRV
3556
ILTEK
3561
QELEA
3566
ERVKL
3571
LEDVT
3576
FNKRK
3581
MKELE
3586
DNLLY
3591
KLSAT
3596
KGSLV
3601
DDESL
3606
IGVLR
3611
TTKQT
3616
AAEVS
3621
EKLHV
3626
AAETE
3631
IKINA
3636
AQEEF
3641
RPAAT
3646
RGSIL
3651
YFLIT
3656
EMSMV
3661
NIMYQ
3666
TSLAQ
3671
FLKLF
3676
DQSMA
3681
RSEKS
3686
PLPQK
3691
RITNI
3696
IEYLT
3701
YEVFT
3706
YSVRG
3711
LYENH
3716
KFLFV
3721
LLMTL
3726
KIDLQ
3731
RGTVK
3736
HREFQ
3741
ALIKG
3746
GAALD
3751
LKACP
3756
PKPYR
3761
WILDM
3766
TWLNL
3771
VELSK
3776
LPQFA
3781
EIMNQ
3786
ISRNE
3791
KGWKS
3796
WFDKD
3801
APEEE
3806
IIPDG
3811
YNDSL
3816
DTCHK
3821
LLLIR
3826
SWCPD
3831
RTVFQ
3836
ARKYI
3841
ADSLE
3846
EKYTE
3851
PVILN
3856
LEKTW
3861
EESDT
3866
RTPLI
3871
CFLSM
3876
GSDPT
3881
NQIDA
3886
LAKKL
3891
KLECR
3896
TISMG
3901
QGQEV
3906
HARKL
3911
IQMSM
3916
QQGGW
3921
VLLQN
3926
CHLGL
3931
EFMEE
3936
LLETL
3941
ITTEA
3946
SDDSF
3951
RVWIT
3956
TEPHD
3961
RFPIT
3966
LLQTS
3971
LKFTN
3976
EPPQG
3981
VRAGL
3986
KRTFA
3991
GINQD
3996
LLDIS
4001
NLPMW
4006
KPMLY
4011
TVAFL
4016
HSTVQ
4021
ERRKF
4026
GPLGW
4031
NIPYE
4036
FNSAD
4041
FSASV
4046
QFIQN
4051
HLDEC
4056
DIKKG
4061
VSWNT
4066
VRYMI
4071
GEVQY
4076
GGRVT
4081
DDFDK
4086
RLLNC
4091
FARVW
4096
FSEKM
4101
FEPSF
4106
CFYTG
4111
YKIPL
4116
CKTLD
4121
QYFEY
4126
IQSLP
4131
SLDNP
4136
EVFGL
4141
HPNAD
4146
ITYQS
4151
NTASA
4156
VLETI
4161
TNIQP
4166
KESGG
4171
GVGET
4176
REAIV
4181
YRLSE
4186
DMLSK
4191
LPPDY
4196
IPHEV
4201
KSRLI
4206
KMGHL
4211
NSMNI
4216
FLRQE
4221
IDRMQ
4226
RVISI
4231
LRSSL
4236
SDLKL
4241
AIEGT
4246
IIMSE
4251
NLRDA
4256
LDNMY
4261
DARIP
4266
QLWKR
4271
VSWDS
4276
STLGF
4281
WFTEL
4286
LERNA
4291
QFSTW
4296
IFEGR
4301
PNVFW
4306
MTGFF
4311
NPQGF
4316
LTAMR
4321
QEVTR
4326
AHKGW
4331
ALDTV
4336
TIHNE
4341
VLRQT
4346
KEEIT
4351
SPPGE
4356
GVYIY
4361
GLYMD
4366
GAAWD
4371
RRNGK
4376
LMEST
4381
PKVLF
4386
TQLPV
4391
LHIFA
4396
INSTA
4401
PKDPK
4406
LYVCP
4411
IYKKP
4416
RRTDL
4421
TFITV
4426
VYLRT
4431
VLSPD
4436
HWILR
4441
GVALL
4446
CDIK
4451
Mutation Information
DNA mutation:
None
Peptide Range:
3593 ~ 3617
Mut AA position:
3605 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLYKLSATKGSLVDDESLIGVLRTT
||||||||||||.||||||||||||
Mutant:
LLYKLSATKGSLADDESLIGVLRTT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) DNAH8
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay