Immunogenicity 1176
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ATP2B1
Transcript ID
ENST00000428670
HLA INFO
A*29:02
TCR INFO
No TCR info found!
Full length protein sequence (1220 aa)
MGDMA
1
NNSVA
6
YSGVK
11
NSLKE
16
ANHDG
21
DFGIT
26
LAELR
31
ALMEL
36
RSTDA
41
LRKIQ
46
ESYGD
51
VYGIC
56
TKLKT
61
SPNEG
66
LSGNP
71
ADLER
76
REAVF
81
GKNFI
86
PPKKP
91
KTFLQ
96
LVWEA
101
LQDVT
106
LIILE
111
IAAIV
116
SLGLS
121
FYQPP
126
EGDNA
131
LCGEV
136
SVGEE
141
EGEGE
146
TGWIE
151
GAAIL
156
LSVVC
161
VVLVT
166
AFNDW
171
SKEKQ
176
FRGLQ
181
SRIEQ
186
EQKFT
191
VIRGG
196
QVIQI
201
PVADI
206
TVGDI
211
AQVKY
216
GDLLP
221
ADGIL
226
IQGND
231
LKIDE
236
SSLTG
241
ESDHV
246
KKSLD
251
KDPLL
256
LSGTH
261
VMEGS
266
GRMVV
271
TAVGV
276
NSQTG
281
IIFTL
286
LGAGG
291
EEEEK
296
KDEKK
301
KEKKN
306
KKQDG
311
AIENR
316
NKAKA
321
QDGAA
326
MEMQP
331
LKSEE
336
GGDGD
341
EKDKK
346
KANLP
351
KKEKS
356
VLQGK
361
LTKLA
366
VQIGK
371
AGLLM
376
SAITV
381
IILVL
386
YFVID
391
TFWVQ
396
KRPWL
401
AECTP
406
IYIQY
411
FVKFF
416
IIGVT
421
VLVVA
426
VPEGL
431
PLAVT
436
ISLAY
441
SVKKM
446
MKDNN
451
LVRHL
456
DACET
461
MGNAT
466
AICSD
471
KTGTL
476
TMNRM
481
TVVQA
486
YINEK
491
HYKKV
496
PEPEA
501
IPPNI
506
LSYLV
511
TGISV
516
NCAYT
521
SKILP
526
PEKEG
531
GLPRH
536
VGNKT
541
ECALL
546
GLLLD
551
LKRDY
556
QDVRN
561
EIPEE
566
ALYKV
571
YTFNS
576
VRKSM
581
STVLK
586
NSDGS
591
YRIFS
596
KGASE
601
IILKK
606
CFKIL
611
SANGE
616
AKVFR
621
PRDRD
626
DIVKT
631
VIEPM
636
ASEGL
641
RTICL
646
AFRDF
651
PAGEP
656
EPEWD
661
NENDI
666
VTGLT
671
CIAVV
676
GIEDP
681
VRPEV
686
PDAIK
691
KCQRA
696
GITVR
701
MVTGD
706
NINTA
711
RAIAT
716
KCGIL
721
HPGED
726
FLCLE
731
GKDFN
736
RRIRN
741
EKGEI
746
EQERI
751
DKIWP
756
KLRVL
761
ARSSP
766
TDKHT
771
LVKGI
776
IDSTV
781
SDQRQ
786
VVAVT
791
GDGTN
796
DGPAL
801
KKADV
806
GFAMG
811
IAGTD
816
VAKEA
821
SDIIL
826
TDDNF
831
TSIVK
836
AVMWG
841
RNVYD
846
SISKF
851
LQFQL
856
TVNVV
861
AVIVA
866
FTGAC
871
ITQDS
876
PLKAV
881
QMLWV
886
NLIMD
891
TLASL
896
ALATE
901
PPTES
906
LLLRK
911
PYGRN
916
KPLIS
921
RTMMK
926
NILGH
931
AFYQL
936
VVVFT
941
LLFAG
946
EKFFD
951
IDSGR
956
NAPLH
961
APPSE
966
HYTIV
971
FNTFV
976
LMQLF
981
NEINA
986
RKIHG
991
ERNVF
996
EGIFN
1001
NAIFC
1006
TIVLG
1011
TFVVQ
1016
IIIVQ
1021
FGGKP
1026
FSCSE
1031
LSIEQ
1036
WLWSI
1041
FLGMG
1046
TLLWG
1051
QLIST
1056
IPTSR
1061
LKFLK
1066
EAGHG
1071
TQKEE
1076
IPEEE
1081
LAEDV
1086
EEIDH
1091
AEREL
1096
RRGQI
1101
LWFRG
1106
LNRIQ
1111
TQIRV
1116
VNAFR
1121
SSLYE
1126
GLEKP
1131
ESRSS
1136
IHNFM
1141
THPEF
1146
RIEDS
1151
EPHIP
1156
LIDDT
1161
DAEDD
1166
APTKR
1171
NSSPP
1176
PSPNK
1181
NNNAV
1186
DSGIH
1191
LTIEM
1196
NKSAT
1201
SSSPG
1206
SPLHS
1211
LETSL
1216
Mutation Information
DNA mutation:
None
Peptide Range:
775 ~ 799
Mut AA position:
787 (13 in Wild Type peptide)
Alignment
Wild Type:
"TLVKGIIDSTVSDQRQVVAVTGDGT
||||||||||||.||||||||||||
Mutant:
TLVKGIIDSTVSNQRQVVAVTGDGT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ATP2B1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay