Immunogenicity 1178

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ZNF66
Transcript ID
ENST00000344519
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (573 aa)
MGPLQ
1
FRDVA
6
IEFSL
11
EEWHC
16
LDMAQ
21
RNLYR
26
DVMLE
31
NYRNL
36
VFLGI
41
VVSKP
46
DLITH
51
LEQGK
56
KPSTM
61
QRHEM
66
VANPS
71
VLCSH
76
FNQDL
81
WPEQS
86
IKDSF
91
QKLIL
96
RRHKK
101
CGHDN
106
LQLKK
111
GCESV
116
DKCKV
121
HKRGY
126
NGLNQ
131
CLTTT
136
QSKMF
141
QCDKH
146
GKVFH
151
QFSNT
156
NRHKI
161
RHTGK
166
NPCKF
171
TECGK
176
AFNRS
181
STFTT
186
HKKIH
191
TGEKP
196
YKCIE
201
CGKAF
206
NRSSH
211
LTTHK
216
IIHTG
221
EKRYK
226
CEDCG
231
KAFNR
236
SSNLT
241
THKKI
246
HTGEK
251
PYKCE
256
ECGKA
261
FKRSS
266
ILTTH
271
KRIHT
276
GEKPY
281
KCEEC
286
GKVFK
291
YLSSL
296
STHKI
301
IHTGE
306
KPYKC
311
EECGK
316
AFNWS
321
SHLTT
326
HKRIH
331
TGEKP
336
YKCEE
341
CGKGF
346
KYSST
351
LTKHK
356
IIHTG
361
EKPYK
366
CEECG
371
EAFKY
376
SCSLT
381
AHKII
386
HTGKK
391
PYKCE
396
ECGKV
401
FKHSS
406
PLSKH
411
KRIHT
416
GEKPY
421
KCEEC
426
GKAFS
431
RSSIL
436
TTHKI
441
IHTGE
446
KPYEC
451
EDCGK
456
AFNRS
461
SNLTK
466
HKKIH
471
TGEKP
476
YKCEE
481
CGKAF
486
KCSSI
491
LTTHK
496
RIHTA
501
DKPYK
506
CEECG
511
KDFKY
516
SSTLT
521
RHKKI
526
HTGGK
531
PHKCN
536
KCGKA
541
FISSS
546
NLSRH
551
EIIHM
556
GGNPY
561
KCENV
566
AKP
571
Mutation Information
DNA mutation:
None
Peptide Range:
516 ~ 540
Mut AA position:
528 (13 in Wild Type peptide)
Alignment
Wild Type:
"KDFKYSSTLTRHKKIHTGGKPHKCN
||||||||||||.||||||||||||
Mutant:
KDFKYSSTLTRHMKIHTGGKPHKCN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000160229

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay