Immunogenicity 11799
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
LRRC42
Transcript ID
uc001cwk.2
HLA INFO
B*27:02
TCR INFO
No TCR info found!
Full length protein sequence (428 aa)
MSYYL
1
SSENH
6
LDPGP
11
IYMRE
16
NGQLH
21
MVNLA
26
LDGVR
31
SSLQK
36
PRPFR
41
LFPKG
46
FSVEL
51
CMNRE
56
DDTAR
61
KEKTD
66
HFIFT
71
YTREG
76
NLRYS
81
AKSLF
86
SLVLG
91
FISDN
96
VDHID
101
SLIGF
106
PEQIA
111
EKLFS
116
AAEAR
121
QKFTE
126
PGAGL
131
RALQK
136
FTEAY
141
GSLVL
146
CSLCL
151
RNRYL
156
VISEK
161
LEEIK
166
SFREL
171
TCLDL
176
SCCKL
181
GDEHE
186
LLEHL
191
TNEAL
196
SSVTQ
201
LHLKD
206
NCLSD
211
AGVRK
216
MTAPV
221
RVMKR
226
GLENL
231
TLLDL
236
SCNPE
241
ITDAG
246
IGYLF
251
SFRKL
256
NCLDI
261
SGTGL
266
KDIKT
271
VKHKL
276
QTHIG
281
LVHSK
286
VPLKE
291
FDHSN
296
CKTEG
301
WADQI
306
VLQWE
311
RVTAE
316
AVKPR
321
ETSEP
326
RAAAQ
331
RFYGK
336
RSRAE
341
APLKC
346
PLADT
351
HMNSS
356
EKLQF
361
YKEKA
366
PDCHG
371
PVLKH
376
EAISS
381
QESKK
386
SKKRP
391
FEESE
396
TEQNN
401
SSQPS
406
KQKYV
411
CLAVE
416
DWDLL
421
NSY
426
Mutation Information
DNA mutation:
None
Peptide Range:
120 ~ 144
Mut AA position:
132 (13 in Wild Type peptide)
Alignment
Wild Type:
"SAAEARQKFTEPGAGLRALQKFTEA
||||||||||||.||||||||||||
Mutant:
SAAEARQKFTEPDAGLRALQKFTEA"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) LRRC42
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay