Immunogenicity 1189

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
NRXN3
Transcript ID
ENST00000428277
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (459 aa)
MHLRI
1
HARRS
6
PPRRP
11
AWTLG
16
IWFLF
21
WGCIV
26
SSVWS
31
SSNVA
36
SSSST
41
SSSPG
46
SHSQH
51
EHHFH
56
GSKHH
61
SVPIS
66
IYRSP
71
VSLRG
76
GHAGA
81
TYIFG
86
KSGGL
91
ILYTW
96
PANDR
101
PSTRS
106
DRLAV
111
GFSTT
116
VKDGI
121
LVRID
126
SAPGL
131
GDFLQ
136
LHIEQ
141
GKIGV
146
VFNIG
151
TVDIS
156
IKEER
161
TPVND
166
GKYHV
171
VRFTR
176
NGGNA
181
TLQVD
186
NWPVN
191
EHYPT
196
GNTDN
201
ERFQM
206
VKQKI
211
PFKYN
216
RPVEE
221
WLQEK
226
GRQLT
231
IFNTQ
236
AQIAI
241
GGKDK
246
GRLFQ
251
GQLSG
256
LYYDG
261
LKVLN
266
MAAEN
271
NPNIK
276
INGSV
281
RLVGE
286
VPSIL
291
GTTQT
296
TSMPP
301
EMSTT
306
VMETT
311
TTMAT
316
TTTRK
321
NRSTA
326
SIQPT
331
SDDLV
336
SSAEC
341
SSDDE
346
DFVEC
351
EPSTA
356
NPTEP
361
GIRRV
366
PGASE
371
VIRES
376
SSTTG
381
MVVGI
386
VAAAA
391
LCILI
396
LLYAM
401
YKYRN
406
RDEGS
411
YQVDE
416
TRNYI
421
SNSAQ
426
SNGTL
431
MKEKQ
436
QSSKS
441
GHKKQ
446
KNKDR
451
EYYV
456
Mutation Information
DNA mutation:
None
Peptide Range:
357 ~ 381
Mut AA position:
369 (13 in Wild Type peptide)
Alignment
Wild Type:
"PSTANPTEPGIRRVPGASEVIRESS
||||||||||||.||||||||||||
Mutant:
PSTANPTEPGIRQVPGASEVIRESS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NRXN3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay