Immunogenicity 11899

summary
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
NES
Transcript ID
uc001fpq.3
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (1621 aa)
MEGCM
1
GEESF
6
QMWEL
11
NRRLE
16
AYLAR
21
VKALE
26
EQNEL
31
LSAEL
36
GGLRA
41
QSADT
46
SWRAH
51
ADDEL
56
AALRA
61
LVDQR
66
WREKH
71
AAEVA
76
RDNLA
81
EELEG
86
VAGRC
91
QQLRL
96
ARERT
101
TEEVA
106
RNRRA
111
VEAEK
116
CARAW
121
LSSQV
126
AELER
131
ELEAL
136
RVAHE
141
EERVG
146
LNAQA
151
ACAPR
156
CPAPP
161
RGPPA
166
PAPEV
171
EELAR
176
RLGEA
181
WRGAV
186
RGYQE
191
RVAHM
196
ETSLG
201
QARER
206
LGRAV
211
QGARE
216
GRLEL
221
QQLQA
226
ERGGL
231
LERRA
236
ALEQR
241
LEGRW
246
QERLR
251
ATEKF
256
QLAVE
261
ALEQE
266
KQGLQ
271
SQIAQ
276
VLEGR
281
QQLAH
286
LKMSL
291
SLEVA
296
TYRTL
301
LEAEN
306
SRLQT
311
PGGGS
316
KTSLS
321
FQDPK
326
LELQF
331
PRTPE
336
GRRLG
341
SLLPV
346
LSPTS
351
LPSPL
356
PATLE
361
TPVPA
366
FLKNQ
371
EFLQA
376
RTPTL
381
ASTPI
386
PPTPQ
391
APSPA
396
VDAEI
401
RAQDA
406
PLSLL
411
QTQGG
416
RKQAP
421
EPLRA
426
EARVA
431
IPASV
436
LPGPE
441
EPGGQ
446
RQEAS
451
TGQSP
456
EDHAS
461
LAPPL
466
SPDHS
471
SLEAK
476
DGESG
481
GSRVF
486
SICRG
491
EGEGQ
496
IWGLV
501
EKETA
506
IEGKV
511
VSSLQ
516
QEIWE
521
EEDLN
526
RKEIQ
531
DSQVP
536
LEKET
541
LKSLG
546
EEIQE
551
SLKTL
556
ENQSH
561
ETLER
566
ENQEC
571
PRSLE
576
EDLET
581
LKSLE
586
KENKE
591
LLKDV
596
EVVRP
601
LEKEA
606
VGQLK
611
PTGKE
616
DTQTL
621
QSLQK
626
ENQEL
631
MKSLE
636
GNLET
641
FLFPG
646
TENQE
651
LVSSL
656
QENLE
661
SLTAL
666
EKENQ
671
EPLRS
676
PEVGD
681
EEALR
686
PLTKE
691
NQEPL
696
RSLED
701
ENKEA
706
FRSLE
711
KENQE
716
PLKTL
721
EEEDQ
726
SIVRP
731
LETEN
736
HKSLR
741
SLEEQ
746
DQETL
751
RTLEK
756
ETQQR
761
RRSLG
766
EQDQM
771
TLRPP
776
EKVDL
781
EPLKS
786
LDQEI
791
ARPLE
796
NENQE
801
FLKSL
806
KEESV
811
EAVKS
816
LETEI
821
LESLK
826
SAGQE
831
NLETL
836
KSPET
841
QAPLW
846
TPEEI
851
NQGAM
856
NPLEK
861
EIQEP
866
LESVE
871
VNQET
876
FRLLE
881
EENQE
886
SLRSL
891
GAWNL
896
ENLRS
901
PEEVD
906
KESQR
911
NLEEE
916
ENLGK
921
GEYQE
926
SLRSL
931
EEEGQ
936
ELPQS
941
ADVQR
946
WEDTV
951
EKDQE
956
LAQES
961
PPGMA
966
GVENE
971
DEAEL
976
NLREQ
981
DGFTG
986
KEEVV
991
EQGEL
996
NATEE
1001
VWIPG
1006
EGHPE
1011
SPEPK
1016
EQRGL
1021
VEGAS
1026
VKGGA
1031
EGLQD
1036
PEGQS
1041
QQVGA
1046
PGLQA
1051
PQGLP
1056
EAIEP
1061
LVEDD
1066
VAPGG
1071
DQASP
1076
EVMLG
1081
SEPAM
1086
GESAA
1091
GAEPG
1096
PGQGV
1101
GGLGD
1106
PGHLT
1111
REEVM
1116
EPPLE
1121
EESLE
1126
AKRVQ
1131
GLEGP
1136
RKDLE
1141
EAGGL
1146
GTEFS
1151
ELPGK
1156
SRDPW
1161
EPPRE
1166
GREES
1171
EAEAP
1176
RGAEE
1181
AFPAE
1186
TLGHT
1191
GSDAP
1196
SPWPL
1201
GSEEA
1206
EEDVP
1211
PVLVS
1216
PSPTY
1221
TPILE
1226
DAPGP
1231
QPQAE
1236
GSQEA
1241
SWGVQ
1246
GRAEA
1251
LGKVE
1256
SEQEE
1261
LGSGE
1266
IPEGP
1271
QEEGE
1276
ESREE
1281
SEEDE
1286
LGETL
1291
PDSTP
1296
LGFYL
1301
RSPTS
1306
PRWDP
1311
TGEQR
1316
PPPQG
1321
ETGKE
1326
GWDPA
1331
VLASE
1336
GLEAP
1341
PSEKE
1346
EGEEG
1351
EEECG
1356
RDSDL
1361
SEEFE
1366
DLGTE
1371
APFLP
1376
GVPGE
1381
VAEPL
1386
GQVPQ
1391
LLLDP
1396
AAWDR
1401
DGESD
1406
GFADE
1411
EESGE
1416
EGEED
1421
QEEGR
1426
EPGAG
1431
RWGPG
1436
SSVGS
1441
LQALS
1446
SSQRG
1451
EFLES
1456
DSVSV
1461
SVPWD
1466
DSLRG
1471
AVAGA
1476
PKTAL
1481
ETESQ
1486
DSAEP
1491
SGSEE
1496
ESDPV
1501
SLERE
1506
DKVPG
1511
PLEIP
1516
SGMED
1521
AGPGA
1526
DIIGV
1531
NGQGP
1536
NLEGK
1541
SQHVN
1546
GGVMN
1551
GLEQS
1556
EEVGQ
1561
GMPLV
1566
SEGDR
1571
GSPFQ
1576
EEEGS
1581
ALKTS
1586
WAGAP
1591
VHLGQ
1596
GQFLK
1601
FTQRE
1606
GDRES
1611
WSSGE
1616
D
1621
Mutation Information
DNA mutation:
None
Peptide Range:
193 ~ 217
Mut AA position:
205 (13 in Wild Type peptide)
Alignment
Wild Type:
"YQERVAHMETSLGQARERLGRAVQG
||||||||||||.||||||||||||
Mutant:
YQERVAHMETSLDQARERLGRAVQG"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay