Immunogenicity 11918
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MNDA
Transcript ID
uc001fsz.1
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (407 aa)
MVNEY
1
KKILL
6
LKGFE
11
LMDDY
16
HFTSI
21
KSLLA
26
YDLGL
31
TTKMQ
36
EEYNR
41
IKITD
46
LMEKK
51
FQGVA
56
CLDKL
61
IELAK
66
DMPSL
71
KNLVN
76
NLRKE
81
KSKVA
86
KKIKT
91
QEKAP
96
VKKIN
101
QEEVG
106
LAAPA
111
PTARN
116
KLTSE
121
ARGRI
126
PVAQK
131
RKTPN
136
KEKTE
141
AKRNK
146
VSQEQ
151
SKPPG
156
PSGAS
161
TSAAV
166
DHPPL
171
PQTSS
176
STPSN
181
TSFTP
186
NQETQ
191
AQRQV
196
DARRN
201
VPQND
206
PVTVV
211
VLKAT
216
APFKY
221
ESPEN
226
GKSTM
231
FHATV
236
ASKTQ
241
YFHVK
246
VFDIN
251
LKEKF
256
VRKKV
261
ITISD
266
YSECK
271
GVMEI
276
KEASS
281
VSDFN
286
QNFEV
291
PNRII
296
EIANK
301
TPKIS
306
QLYKQ
311
ASGTM
316
VYGLF
321
MLQKK
326
SVHKK
331
NTIYE
336
IQDNT
341
GSMDV
346
VGSGK
351
WHNIK
356
CEKGD
361
KLRLF
366
CLQLR
371
TVDRK
376
LKLVC
381
GSHSF
386
IKVIK
391
AKKNK
396
EGPMN
401
VN
406
Mutation Information
DNA mutation:
None
Peptide Range:
270 ~ 294
Mut AA position:
282 (13 in Wild Type peptide)
Alignment
Wild Type:
"DYSECKGVMEIKEASSVSDFNQNFE
||||||||||||.||||||||||||
Mutant:
DYSECKGVMEIKKASSVSDFNQNFE"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) MNDA
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay