Immunogenicity 11998

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
OPTN
Transcript ID
uc001ily.1
HLA INFO
C*02:02
TCR INFO

No TCR info found!

T cell Tumor cell C*02:02
sequence
Full length protein sequence (571 aa)
MSHQP
1
LSCLT
6
EKEDS
11
PSEST
16
GNGPP
21
HLAHP
26
NLDTF
31
TPEEL
36
LQQMK
41
ELLTE
46
NHQLK
51
EAMKL
56
NNQAM
61
KGRFE
66
ELSAW
71
TEKQK
76
EERQF
81
FEIQS
86
KEAKE
91
RLMAL
96
SHENE
101
KLKEE
106
LGKLK
111
GKSER
116
SSEDP
121
TDDSR
126
LPRAE
131
AEQEK
136
DQLRT
141
QVVRL
146
QAEKA
151
DLLGI
156
VSELQ
161
LKLNS
166
SGSSE
171
DSFVE
176
IRMAE
181
GEAEG
186
SVKEI
191
KHSPG
196
PTRTV
201
STGTS
206
RSADG
211
AKNYF
216
EHEEL
221
TVSQL
226
LLCLR
231
EGNQK
236
VERLE
241
VALKE
246
AKERV
251
SDFEK
256
KTSNR
261
SEIET
266
QTEGS
271
TEKEN
276
DEEKG
281
PETVG
286
SEVEA
291
LNLQV
296
TSLFK
301
ELQEA
306
HTKLS
311
KAELM
316
KKRLQ
321
EKCQA
326
LERKN
331
SAIPS
336
ELNEK
341
QELVY
346
TNKKL
351
ELQVE
356
SMLSE
361
IKMEQ
366
AKTED
371
EKSKL
376
TVLQM
381
THNKL
386
LQEHN
391
NALKT
396
IEELT
401
RKESE
406
KVDRA
411
VLKEL
416
SEKLE
421
LAEKA
426
LASKQ
431
LQMDE
436
MKQTI
441
AKQEE
446
DLETM
451
TILRA
456
QMEVY
461
CSDFH
466
AERAA
471
REKIH
476
EEKEQ
481
LALQL
486
AVLLK
491
ENDAF
496
EDGGR
501
QSLME
506
MQSRH
511
GARTS
516
DSDQQ
521
AYLVQ
526
RGAED
531
RDWRQ
536
QRNIP
541
IHSCP
546
KCGEV
551
LPDID
556
TLQIH
561
VMDCI
566
I
571
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 15
Mut AA position:
3 (3 in Wild Type peptide)
Alignment
Wild Type:
"MSHQPLSCLTEKEDS
||.||||||||||||
Mutant:
MSYQPLSCLTEKEDS"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay