Immunogenicity 12022

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ANK3
Transcript ID
uc001jky.3
HLA INFO
C*02:02
TCR INFO

No TCR info found!

T cell Tumor cell C*02:02
sequence
Full length protein sequence (4377 aa)
MAHAA
1
SQLKK
6
NRDLE
11
INAEE
16
EPEKK
21
RKHRK
26
RSRDR
31
KKKSD
36
ANASY
41
LRAAR
46
AGHLE
51
KALDY
56
IKNGV
61
DINIC
66
NQNGL
71
NALHL
76
ASKEG
81
HVEVV
86
SELLQ
91
REANV
96
DAATK
101
KGNTA
106
LHIAS
111
LAGQA
116
EVVKV
121
LVTNG
126
ANVNA
131
QSQNG
136
FTPLY
141
MAAQE
146
NHLEV
151
VKFLL
156
DNGAS
161
QSLAT
166
EDGFT
171
PLAVA
176
LQQGH
181
DQVVS
186
LLLEN
191
DTKGK
196
VRLPA
201
LHIAA
206
RKDDT
211
KAAAL
216
LLQND
221
NNADV
226
ESKSG
231
FTPLH
236
IAAHY
241
GNINV
246
ATLLL
251
NRAAA
256
VDFTA
261
RNDIT
266
PLHVA
271
SKRGN
276
ANMVK
281
LLLDR
286
GAKID
291
AKTRD
296
GLTPL
301
HCGAR
306
SGHEQ
311
VVEML
316
LDRAA
321
PILSK
326
TKNGL
331
SPLHM
336
ATQGD
341
HLNCV
346
QLLLQ
351
HNVPV
356
DDVTN
361
DYLTA
366
LHVAA
371
HCGHY
376
KVAKV
381
LLDKK
386
ANPNA
391
KALNG
396
FTPLH
401
IACKK
406
NRIKV
411
MELLL
416
KHGAS
421
IQAVT
426
ESGLT
431
PIHVA
436
AFMGH
441
VNIVS
446
QLMHH
451
GASPN
456
TTNVR
461
GETAL
466
HMAAR
471
SGQAE
476
VVRYL
481
VQDGA
486
QVEAK
491
AKDDQ
496
TPLHI
501
SARLG
506
KADIV
511
QQLLQ
516
QGASP
521
NAATT
526
SGYTP
531
LHLSA
536
REGHE
541
DVAAF
546
LLDHG
551
ASLSI
556
TTKKG
561
FTPLH
566
VAAKY
571
GKLEV
576
ANLLL
581
QKSAS
586
PDAAG
591
KSGLT
596
PLHVA
601
AHYDN
606
QKVAL
611
LLLDQ
616
GASPH
621
AAAKN
626
GYTPL
631
HIAAK
636
KNQMD
641
IATTL
646
LEYGA
651
DANAV
656
TRQGI
661
ASVHL
666
AAQEG
671
HVDMV
676
SLLLG
681
RNANV
686
NLSNK
691
SGLTP
696
LHLAA
701
QEDRV
706
NVAEV
711
LVNQG
716
AHVDA
721
QTKMG
726
YTPLH
731
VGCHY
736
GNIKI
741
VNFLL
746
QHSAK
751
VNAKT
756
KNGYT
761
PLHQA
766
AQQGH
771
THIIN
776
VLLQN
781
NASPN
786
ELTVN
791
GNTAL
796
GIARR
801
LGYIS
806
VVDTL
811
KIVTE
816
ETMTT
821
TTVTE
826
KHKMN
831
VPETM
836
NEVLD
841
MSDDE
846
VRKAN
851
APEML
856
SDGEY
861
ISDVE
866
EGEDA
871
MTGDT
876
DKYLG
881
PQDLK
886
ELGDD
891
SLPAE
896
GYMGF
901
SLGAR
906
SASLR
911
SFSSD
916
RSYTL
921
NRSSY
926
ARDSM
931
MIEEL
936
LVPSK
941
EQHLT
946
FTREF
951
DSDSL
956
RHYSW
961
AADTL
966
DNVNL
971
VSSPI
976
HSGFL
981
VSFMV
986
DARGG
991
SMRGS
996
RHHGM
1001
RIIIP
1006
PRKCT
1011
APTRI
1016
TCRLV
1021
KRHKL
1026
ANPPP
1031
MVEGE
1036
GLASR
1041
LVEMG
1046
PAGAQ
1051
FLGPV
1056
IVEIP
1061
HFGSM
1066
RGKER
1071
ELIVL
1076
RSENG
1081
ETWKE
1086
HQFDS
1091
KNEDL
1096
TELLN
1101
GMDEE
1106
LDSPE
1111
ELGKK
1116
RICRI
1121
ITKDF
1126
PQYFA
1131
VVSRI
1136
KQESN
1141
QIGPE
1146
GGILS
1151
STTVP
1156
LVQAS
1161
FPEGA
1166
LTKRI
1171
RVGLQ
1176
AQPVP
1181
DEIVK
1186
KILGN
1191
KATFS
1196
PIVTV
1201
EPRRR
1206
KFHKP
1211
ITMTI
1216
PVPPP
1221
SGEGV
1226
SNGYK
1231
GDTTP
1236
NLRLL
1241
CSITG
1246
GTSPA
1251
QWEDI
1256
TGTTP
1261
LTFIK
1266
DCVSF
1271
TTNVS
1276
ARFWL
1281
ADCHQ
1286
VLETV
1291
GLATQ
1296
LYREL
1301
ICVPY
1306
MAKFV
1311
VFAKM
1316
NDPVE
1321
SSLRC
1326
FCMTD
1331
DKVDK
1336
TLEQQ
1341
ENFEE
1346
VARSK
1351
DIEVL
1356
EGKPI
1361
YVDCY
1366
GNLAP
1371
LTKGG
1376
QQLVF
1381
NFYSF
1386
KENRL
1391
PFSIK
1396
IRDTS
1401
QEPCG
1406
RLSFL
1411
KEPKT
1416
TKGLP
1421
QTAVC
1426
NLNIT
1431
LPAHK
1436
KETES
1441
DQDDE
1446
IEKTD
1451
RRQSF
1456
ASLAL
1461
RKRYS
1466
YLTEP
1471
GMIER
1476
STGAT
1481
RSLPT
1486
TYSYK
1491
PFFST
1496
RPYQS
1501
WTTAP
1506
ITVPG
1511
PAKSG
1516
FTSLS
1521
SSSSN
1526
TPSAS
1531
PLKSI
1536
WSVST
1541
PSPIK
1546
STLGA
1551
STTSS
1556
VKSIS
1561
DVASP
1566
IRSFR
1571
TMSSP
1576
IKTVV
1581
SQSPY
1586
NIQVS
1591
SGTLA
1596
RAPAV
1601
TEATP
1606
LKGLA
1611
SNSTF
1616
SSRTS
1621
PVTTA
1626
GSLLE
1631
RSSIT
1636
MTPPA
1641
SPKSN
1646
INMYS
1651
SSLPF
1656
KSIIT
1661
SAAPL
1666
ISSPL
1671
KSVVS
1676
PVKSA
1681
VDVIS
1686
SAKIT
1691
MASSL
1696
SSPVK
1701
QMPGH
1706
AEVAL
1711
VNGSI
1716
SPLKY
1721
PSSST
1726
LINGC
1731
KATAT
1736
LQEKI
1741
SSATN
1746
SVSSV
1751
VSAAT
1756
DTVEK
1761
VFSTT
1766
TAMPF
1771
SPLRS
1776
YVSAA
1781
PSAFQ
1786
SLRTP
1791
SASAL
1796
YTSLG
1801
SSISA
1806
TTSSV
1811
TSSII
1816
TVPVY
1821
SVVNV
1826
LPEPA
1831
LKKLP
1836
DSNSF
1841
TKSAA
1846
ALLSP
1851
IKTLT
1856
TETHP
1861
QPHFS
1866
RTSSP
1871
VKSSL
1876
FLAPS
1881
ALKLS
1886
TPSSL
1891
SSSQE
1896
ILKDV
1901
AEMKE
1906
DLMRM
1911
TAILQ
1916
TDVPE
1921
EKPFQ
1926
PELPK
1931
EGRID
1936
DEEPF
1941
KIVEK
1946
VKEDL
1951
VKVSE
1956
ILKKD
1961
VCVDN
1966
KGSPK
1971
SPKSD
1976
KGHSP
1981
EDDWI
1986
EFSSE
1991
EIREA
1996
RQQAA
2001
ASQSP
2006
SLPER
2011
VQVKA
2016
KAASE
2021
KDYNL
2026
TKVID
2031
YLTND
2036
IGSSS
2041
LTNLK
2046
YKFED
2051
AKKDG
2056
EERQK
2061
RVLKP
2066
AIALQ
2071
EHKLK
2076
MPPAS
2081
MRTST
2086
SEKEL
2091
CKMAD
2096
SFFGT
2101
DTILE
2106
SPDDF
2111
SQHDQ
2116
DKSPL
2121
SDSGF
2126
ETRSE
2131
KTPSA
2136
PQSAE
2141
STGPK
2146
PLFHE
2151
VPIPP
2156
VITET
2161
RTEVV
2166
HVIRS
2171
YDPSA
2176
GDVPQ
2181
TQPEE
2186
PVSPK
2191
PSPTF
2196
MELEP
2201
KPTTS
2206
SIKEK
2211
VKAFQ
2216
MKASS
2221
EEDDH
2226
NRVLS
2231
KGMRV
2236
KEETH
2241
ITTTT
2246
RMVYH
2251
SPPGG
2256
EGASE
2261
RIEET
2266
MSVHD
2271
IMKAF
2276
QSGRD
2281
PSKEL
2286
AGLFE
2291
HKSAV
2296
SPDVH
2301
KSAAE
2306
TSAQH
2311
AEKDN
2316
QMKPK
2321
LERII
2326
EVHIE
2331
KGNQA
2336
EPTEV
2341
IIRET
2346
KKHPE
2351
KEMYV
2356
YQKDL
2361
SRGDI
2366
NLKDF
2371
LPEKH
2376
DAFPC
2381
SEEQG
2386
QQEEE
2391
ELTAE
2396
ESLPS
2401
YLESS
2406
RVNTP
2411
VSQEE
2416
DSRPS
2421
SAQLI
2426
SDDSY
2431
KTLKL
2436
LSQHS
2441
IEYHD
2446
DELSE
2451
LRGES
2456
YRFAE
2461
KMLLS
2466
EKLDV
2471
SHSDT
2476
EESVT
2481
DHAGP
2486
PSSEL
2491
QGSDK
2496
RSREK
2501
IATAP
2506
KKEIL
2511
SKIYK
2516
DVSEN
2521
GVGKV
2526
SKDEH
2531
FDKVT
2536
VLHYS
2541
GNVSS
2546
PKHAM
2551
WMRFT
2556
EDRLD
2561
RGREK
2566
LIYED
2571
RVDRT
2576
VKEAE
2581
EKLTE
2586
VSQFF
2591
RDKTE
2596
KLNDE
2601
LQSPE
2606
KKARP
2611
KNGKE
2616
YSSQS
2621
PTSSS
2626
PEKVL
2631
LTELL
2636
ASNDE
2641
WVKAR
2646
QHGPD
2651
GQGFP
2656
KAEEK
2661
APSLP
2666
SSPEK
2671
MVLSQ
2676
QTEDS
2681
KSTVE
2686
AKGSI
2691
SQSKA
2696
PDGPQ
2701
SGFQL
2706
KQSKL
2711
SSIRL
2716
KFEQG
2721
THAKS
2726
KDMSQ
2731
EDRKS
2736
DGQSR
2741
IPVKK
2746
IQESK
2751
LPVYQ
2756
VFARE
2761
KQQKA
2766
IDLPD
2771
ESVSV
2776
QKDFM
2781
VLKTK
2786
DEHAQ
2791
SNEIV
2796
VNDSG
2801
SDNVK
2806
KQRTE
2811
MSSKA
2816
MPDSF
2821
SEQQA
2826
KDLAC
2831
HITSD
2836
LATRG
2841
PWDKK
2846
VFRTW
2851
ESSGA
2856
TNNKS
2861
QKEKL
2866
SHVLV
2871
HDVRE
2876
NHIGH
2881
PESKS
2886
VDQKN
2891
EFMSV
2896
TERER
2901
KLLTN
2906
GSLSE
2911
IKEMT
2916
VKSPS
2921
KKVLY
2926
REYVV
2931
KEGDH
2936
PGGLL
2941
DQPSR
2946
RSESS
2951
AVSHI
2956
PVRVA
2961
DERRM
2966
LSSNI
2971
PDGFC
2976
EQSAF
2981
PKHEL
2986
SQKLS
2991
QSSMS
2996
KETVE
3001
TQHFN
3006
SIEDE
3011
KVTYS
3016
EISKV
3021
SKHQS
3026
YVGLC
3031
PPLEE
3036
TETSP
3041
TKSPD
3046
SLEFS
3051
PGKES
3056
PSSDV
3061
FDHSP
3066
IDGLE
3071
KLAPL
3076
AQTEG
3081
GKEIK
3086
TLPVY
3091
VSFVQ
3096
VGKQY
3101
EKEIQ
3106
QGGVK
3111
KIISQ
3116
ECKTV
3121
QETRG
3126
TFYTT
3131
RQQKQ
3136
PPSPQ
3141
GSPED
3146
DTLEQ
3151
VSFLD
3156
SSGKS
3161
PLTPE
3166
TPSSE
3171
EVSYE
3176
FTSKT
3181
PDSLI
3186
AYIPG
3191
KPSPI
3196
PEVSE
3201
ESEEE
3206
EQAKS
3211
TSLKQ
3216
TTVEE
3221
TAVER
3226
EMPND
3231
VSKDS
3236
NQRPK
3241
NNRVA
3246
YIEFP
3251
PPPPL
3256
DADQI
3261
ESDKK
3266
HHYLP
3271
EKEVD
3276
MIEVN
3281
LQDEH
3286
DKYQL
3291
AEPVI
3296
RVQPP
3301
SPVPP
3306
GADVS
3311
DSSDD
3316
ESIYQ
3321
PVPVK
3326
KYTFK
3331
LKEVD
3336
DEQKE
3341
KPKAS
3346
AEKAS
3351
NQKEL
3356
ESNGS
3361
GKDNE
3366
FGLGL
3371
DSPQN
3376
EIAQN
3381
GNNDQ
3386
SITEC
3391
SIATT
3396
AEFSH
3401
DTDAT
3406
EIDSL
3411
DGYDL
3416
QDEDD
3421
GLTES
3426
DSKLP
3431
IQAME
3436
IKKDI
3441
WNTEG
3446
ILKPA
3451
DRSFS
3456
QSKLE
3461
VIEEE
3466
GKVGP
3471
DEDKP
3476
PSKSS
3481
SSEKT
3486
PDKTD
3491
QKSGA
3496
QFFTL
3501
EGRHP
3506
DRSVF
3511
PDTYF
3516
SYKVD
3521
EEFAT
3526
PFKTV
3531
ATKGL
3536
DFDPW
3541
SNNRG
3546
DDEVF
3551
DSKSR
3556
EDETK
3561
PFGLA
3566
VEDRS
3571
PATTP
3576
DTTPA
3581
RTPTD
3586
ESTPT
3591
SEPNP
3596
FPFHE
3601
GKMFE
3606
MTRSG
3611
AIDMS
3616
KRDFV
3621
EERLQ
3626
FFQIG
3631
EHTSE
3636
GKSGD
3641
QGEGD
3646
KSMVT
3651
ATPQP
3656
QSGDT
3661
TVETN
3666
LERNV
3671
ETPTV
3676
EPNPS
3681
IPTSG
3686
ECQEG
3691
TSSSG
3696
SLEKS
3701
AAATN
3706
TSKVD
3711
PKLRT
3716
PIKMG
3721
ISAST
3726
MTMKK
3731
EGPGE
3736
ITDKI
3741
EAVMT
3746
SCQGL
3751
ENETI
3756
TMISN
3761
TANSQ
3766
MGVRP
3771
HEKHD
3776
FQKDN
3781
FNNNN
3786
NLDSS
3791
TIQTD
3796
NIMSN
3801
IVLTE
3806
HSAPT
3811
CTTEK
3816
DNPVK
3821
VSSGK
3826
KTGVL
3831
QGHCV
3836
RDKQK
3841
VLGEQ
3846
QKTKE
3851
LIGIR
3856
QKSKL
3861
PIKAT
3866
SPKDT
3871
FPPNH
3876
MSNTK
3881
ASKMK
3886
QVSQS
3891
EKTKA
3896
LTTSS
3901
CVDVK
3906
SRIPV
3911
KNTHR
3916
DNIIA
3921
VRKAC
3926
ATQKQ
3931
GQPEK
3936
GKAKQ
3941
LPSKL
3946
PVKVR
3951
STCVT
3956
TTTTT
3961
ATTTT
3966
TTTTT
3971
TTTSC
3976
TVKVR
3981
KSQLK
3986
EVCKH
3991
SIEYF
3996
KGISG
4001
ETLKL
4006
VDRLS
4011
EEEKK
4016
MQSEL
4021
SDEEE
4026
STSRN
4031
TSLSE
4036
TSRGG
4041
QPSVT
4046
TKSAR
4051
DKKTE
4056
AAPLK
4061
SKSEK
4066
AGSEK
4071
RSSRR
4076
TGPQS
4081
PCERT
4086
DIRMA
4091
IVADH
4096
LGLSW
4101
TELAR
4106
ELNFS
4111
VDEIN
4116
QIRVE
4121
NPNSL
4126
ISQSF
4131
MLLKK
4136
WVTRD
4141
GKNAT
4146
TDALT
4151
SVLTK
4156
INRID
4161
IVTLL
4166
EGPIF
4171
DYGNI
4176
SGTRS
4181
FADEN
4186
NVFHD
4191
PVDGW
4196
QNETS
4201
SGNLE
4206
SCAQA
4211
RRVTG
4216
GLLDR
4221
LDDSP
4226
DQCRD
4231
SITSY
4236
LKGEA
4241
GKFEA
4246
NGSHT
4251
EITPE
4256
AKTKS
4261
YFPES
4266
QNDVG
4271
KQSTK
4276
ETLKP
4281
KIHGS
4286
GHVEE
4291
PASPL
4296
AAYQK
4301
SLEET
4306
SKLII
4311
EETKP
4316
CVPVS
4321
MKKMS
4326
RTSPA
4331
DGKPR
4336
LSLHE
4341
EEGSS
4346
GSEQK
4351
QGEGF
4356
KVKTK
4361
KEIRH
4366
VEKKS
4371
HS
4376
Mutation Information
DNA mutation:
None
Peptide Range:
2129 ~ 2153
Mut AA position:
2141 (13 in Wild Type peptide)
Alignment
Wild Type:
"GFETRSEKTPSAPQSAESTGPKPLF
||||||||||||.||||||||||||
Mutant:
GFETRSEKTPSASQSAESTGPKPLF"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay