Immunogenicity 1205

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GAS2L2
Transcript ID
ENST00000254466
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (880 aa)
MSQPA
1
GGRRK
6
PRTLG
11
PPVCS
16
IRPFK
21
SSEQY
26
LEAMK
31
EDLAE
36
WLRDL
41
YGLDI
46
DAANF
51
LQVLE
56
TGLVL
61
CQHAN
66
VVTDA
71
ALAFL
76
AEAPA
81
QAQKI
86
PMPRV
91
GVSCN
96
GAAQP
101
GTFQA
106
RDNVS
111
NFIQW
116
CRKEM
121
GIQEV
126
LMFET
131
EDLVL
136
RKNVK
141
NVVLC
146
LLELG
151
RRAWR
156
FGVAA
161
PTLVQ
166
LEEEI
171
EEEVR
176
RELAL
181
PPPDP
186
SPPAP
191
PRRQP
196
CHFRN
201
LDQMV
206
QSLVS
211
HCTCP
216
VQFSM
221
VKVSE
226
GKYRV
231
GDSNT
236
LIFIR
241
ILRNH
246
VMVRV
251
GGGWD
256
TLGHY
261
LDKHD
266
PCRCT
271
SLSHK
276
PGSFL
281
KPPAP
286
PVQHE
291
VRVQD
296
GPSQT
301
QPTMT
306
ISRSQ
311
SPPPP
316
VDWKT
321
YTSSD
326
RRLRP
331
PTPSS
336
PRPRR
341
ERGAG
346
TGASR
351
EMAPF
356
LRCQE
361
RSLIP
366
SWRQP
371
TAGDS
376
PPSPQ
381
SSSTQ
386
KGRDP
391
QCTSS
396
GKREE
401
RYPPE
406
LPRGR
411
IPTSW
416
VHEET
421
DSWGT
426
DAGNP
431
TPQRL
436
RAIEA
441
TTKGI
446
SARGP
451
SPLPR
456
SFGPA
461
ECLGL
466
RLPLR
471
DEAKG
476
AFFQF
481
REPES
486
VRSPT
491
PVQGL
496
TKIPI
501
RLPPA
506
RPPTP
511
GRSFP
516
GATSG
521
SPRTE
526
LGRDP
531
IPLRA
536
VTVDL
541
AGSTH
546
GDCSV
551
EVRQE
556
DQQLD
561
IQVMA
566
EARES
571
WDLGL
576
QEQEG
581
RYTPL
586
PLGGN
591
KEQAI
596
YCSLE
601
EEILG
606
NMKLL
611
EVRSA
616
CPQGT
621
RSGVI
626
PRSGV
631
YIPRL
636
AGQWP
641
EPGGP
646
YDKAI
651
QELAQ
656
GSPSL
661
LKVDL
666
EAWKA
671
APTGS
676
PKPAV
681
TPGPG
686
SLKGK
691
LGARQ
696
SGPRT
701
KASLS
706
AKGTH
711
MRKVP
716
PQGGQ
721
DCSAS
726
TVSAS
731
PEAPT
736
PSPLD
741
PNSDK
746
AKACL
751
SKGRR
756
TLRKP
761
KRVPS
766
IYKLK
771
LRPRI
776
RPRRD
781
HRPEK
786
QPSRI
791
PRPLA
796
YVFLG
801
PARQP
806
PKDRL
811
LRAVL
816
GSKGG
821
EASRV
826
DGASV
831
GEEEE
836
EGKEE
841
KEPAA
846
PLESS
851
PQPPE
856
GLQPH
861
WLNQA
866
PLPPE
871
EESWV
876
Mutation Information
DNA mutation:
None
Peptide Range:
383 ~ 407
Mut AA position:
395 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPQSSSTQKGRDPQCTSSGKREERY
||||||||||||.||||||||||||
Mutant:
SPQSSSTQKGRDSQCTSSGKREERY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GAS2L2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay