Immunogenicity 12070
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
KNDC1
Transcript ID
uc001llz.1
HLA INFO
C*12:03
TCR INFO
No TCR info found!
Full length protein sequence (1749 aa)
MQAMD
1
PAAAD
6
LYEED
11
GKDLD
16
FYDFE
21
PLPTL
26
PEDEE
31
NVSLA
36
DILSL
41
RDRGL
46
SEQEA
51
WAVCL
56
ECSLS
61
MRSVA
66
HAAIF
71
QSLCI
76
TPDTL
81
AFNTS
86
GNVCF
91
MEQLS
96
DDPEG
101
AFVPP
106
EFDVT
111
GNTFE
116
AHIYS
121
LGATL
126
KAALE
131
YVAEP
136
TLEPR
141
LSQDL
146
EALLS
151
RMQAE
156
DPGDR
161
PDLES
166
IIALC
171
EEKLQ
176
LTSSC
181
RVCRS
186
LSAVG
191
RRVLS
196
IESFG
201
ALQDV
206
SESSW
211
RERPA
216
PGNAG
221
PRRPP
226
GDPST
231
DPEVL
236
PTPEG
241
PESET
246
SRGPR
251
ASPTK
256
ALLST
261
PVRNG
266
ESHSR
271
EGLAG
276
LVLDA
281
ERTLG
286
ELDRD
291
ALRRS
296
RLRKV
301
QTFPR
306
LLSDS
311
PEATL
316
CLPLT
321
RGKSQ
326
LPISE
331
LFSPD
336
PRKAF
341
LDRKN
346
GLSSF
351
QAQPK
356
CRLWP
361
EQEPE
366
HQLGR
371
VPCAG
376
RSTDR
381
GPGVP
386
GSPGQ
391
PETSH
396
PSQGP
401
AEAPA
406
DPRDA
411
SGEAQ
416
TPRDD
421
ERIPE
426
GARQL
431
ESAAA
436
EQWVS
441
LQDLL
446
SQLGR
451
PFREY
456
ELWAL
461
CLACL
466
RALQT
471
RPEHP
476
AYLCL
481
DSVLV
486
AEDGA
491
VLFQP
496
PPANG
501
SYDSF
506
FLAPE
511
LAEER
516
LVTEK
521
ASVYC
526
VAAVL
531
WTAAK
536
FSVPR
541
NHKLA
546
LPRRL
551
KTLLL
556
DMARR
561
SAPER
566
PSAAE
571
AIKVC
576
GSYLL
581
QRGMD
586
SRKIL
591
AHLRA
596
SICQV
601
YQEEE
606
TISLQ
611
NAFSV
616
VELKP
621
SVAPA
626
PEPSP
631
GFLPV
636
NSDTG
641
LVAVP
646
GPVPG
651
QHPCG
656
EEATQ
661
LPAAF
666
TSEAT
671
HFKPI
676
VLAQN
681
ASVAR
686
DQPAL
691
AQEES
696
EERGG
701
QREGE
706
GEEKL
711
SLEAH
716
AGSPS
721
LKTPD
726
GPVPG
731
PGPQG
736
AAPEP
741
LGASV
746
QRDSA
751
QGRPC
756
PPPQA
761
PANQP
766
EGASS
771
AAPGS
776
PVPAP
781
PTKAS
786
ALPVE
791
QGPAE
796
PIPPG
801
VASGG
806
LRPDA
811
LGPTT
816
AHHGP
821
RHPPK
826
PPRSK
831
ATERP
836
GQEPE
841
GPGAT
846
PAGER
851
DDQSP
856
DSVPE
861
RPRPA
866
DRRLC
871
LPCVD
876
ASPLP
881
GRTAC
886
PSLQE
891
ATRLI
896
QEEFA
901
FDGYL
906
DNGLE
911
ALIMG
916
EYIFA
921
LKDLT
926
FATFC
931
GAISE
936
KFCDL
941
YWDEK
946
LLQNL
951
FKVVN
956
GQASP
961
SPSTA
966
EEAGS
971
QLEGS
976
QSPRS
981
PSSKR
986
PSLHR
991
LGKEK
996
PAMAR
1001
TSSRA
1006
PCSPT
1011
SVSDV
1016
DSDAL
1021
SRGNF
1026
EVGFR
1031
PQRSV
1036
KAERA
1041
QQPEA
1046
GEDRR
1051
PAGGA
1056
SDVEA
1061
VTRLA
1066
RSKGV
1071
GPALS
1076
PGPAG
1081
FQSCS
1086
PGWCS
1091
AFYEA
1096
DCFGA
1101
DVHNY
1106
VKDLG
1111
RQQAD
1116
GALPD
1121
AQSPE
1126
LEQQL
1131
MMEKR
1136
NYRKT
1141
LKFYQ
1146
KLLQK
1151
EKRNK
1156
GSDVK
1161
TMLSK
1166
LKGQL
1171
EEMKS
1176
RVQFL
1181
SLVKK
1186
YLQVM
1191
YAERW
1196
GLEPC
1201
TLPVI
1206
VNIAA
1211
APCDT
1216
LDFSP
1221
LDESS
1226
SLIFY
1231
NVNKH
1236
PGGRQ
1241
KARIL
1246
QAGTP
1251
LGLMA
1256
YLYSS
1261
DAFLE
1266
GYVQQ
1271
FLYTF
1276
RYFCT
1281
PHDFL
1286
HFLLD
1291
RINST
1296
LTRAH
1301
QDPTS
1306
TFTKI
1311
YRRSL
1316
CVLQA
1321
WVEDC
1326
YAVDF
1331
PRNSG
1336
LLGKL
1341
EDFIS
1346
SKILP
1351
LDGSA
1356
KHLLG
1361
LLEVG
1366
MDRRA
1371
EGNPR
1376
GTDLE
1381
NPREA
1386
EEDAR
1391
PFNAL
1396
CKRLS
1401
EDGIS
1406
RKSFP
1411
WRLPR
1416
GNGLV
1421
LPPHK
1426
ERPYT
1431
IAAAL
1436
PKPCF
1441
LEDFY
1446
GPCAK
1451
TSEKG
1456
PYFLT
1461
EYSTH
1466
QLFSQ
1471
LTLLQ
1476
QELFQ
1481
KCHPV
1486
HFLNS
1491
RALGV
1496
MDKST
1501
AIPKA
1506
SSSES
1511
LSAKT
1516
CSLFL
1521
PNYVQ
1526
DKYLL
1531
QLLRN
1536
ADDVS
1541
TWVAA
1546
EIVTS
1551
HTSKL
1556
QVNLL
1561
SKFLL
1566
IAKSC
1571
YEQRN
1576
FATAM
1581
QILSG
1586
LEHLA
1591
VRQSP
1596
AWRIL
1601
PAKIA
1606
EVMEE
1611
LKAVE
1616
VFLKS
1621
DSLCL
1626
MEGRR
1631
FRAQP
1636
TLPSA
1641
HLLAM
1646
HIQQL
1651
ETGGF
1656
TMTNG
1661
AHRWS
1666
KLRNI
1671
AKVVS
1676
QVHAF
1681
QENPY
1686
TFSPD
1691
PKLQS
1696
YLKQR
1701
IARFS
1706
GADIS
1711
TLAAD
1716
SRANF
1721
HQVSS
1726
EKHSR
1731
KIQDK
1736
LRRMK
1741
ATFQ
1746
Mutation Information
DNA mutation:
None
Peptide Range:
1588 ~ 1612
Mut AA position:
1600 (13 in Wild Type peptide)
Alignment
Wild Type:
"LSGLEHLAVRQSPAWRILPAKIAEV
||||||||||||.||||||||||||
Mutant:
LSGLEHLAVRQSSAWRILPAKIAEV"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) KNDC1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay