Immunogenicity 12172

summary
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SORL1
Transcript ID
uc001pxx.3
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (2214 aa)
MATRS
1
SRRES
6
RLPFL
11
FTLVA
16
LLPPG
21
ALCEV
26
WTQRL
31
HGGSA
36
PLPQD
41
RGFLV
46
VQGDP
51
RELRL
56
WARGD
61
ARGAS
66
RADEK
71
PLRRK
76
RSAAL
81
QPEPI
86
KVYGQ
91
VSLND
96
SHNQM
101
VVHWA
106
GEKSN
111
VIVAL
116
ARDSL
121
ALARP
126
KSSDV
131
YVSYD
136
YGKSF
141
KKISD
146
KLNFG
151
LGNRS
156
EAVIA
161
QFYHS
166
PADNK
171
RYIFA
176
DAYAQ
181
YLWIT
186
FDFCN
191
TLQGF
196
SIPFR
201
AADLL
206
LHSKA
211
SNLLL
216
GFDRS
221
HPNKQ
226
LWKSD
231
DFGQT
236
WIMIQ
241
EHVKS
246
FSWGI
251
DPYDK
256
PNTIY
261
IERHE
266
PSGYS
271
TVFRS
276
TDFFQ
281
SRENQ
286
EVILE
291
EVRDF
296
QLRDK
301
YMFAT
306
KVVHL
311
LGSEQ
316
QSSVQ
321
LWVSF
326
GRKPM
331
RAAQF
336
VTRHP
341
INEYY
346
IADAS
351
EDQVF
356
VCVSH
361
SNNRT
366
NLYIS
371
EAEGL
376
KFSLS
381
LENVL
386
YYSPG
391
GAGSD
396
TLVRY
401
FANEP
406
FADFH
411
RVEGL
416
QGVYI
421
ATLIN
426
GSMNE
431
ENMRS
436
VITFD
441
KGGTW
446
EFLQA
451
PAFTG
456
YGEKI
461
NCELS
466
QGCSL
471
HLAQR
476
LSQLL
481
NLQLR
486
RMPIL
491
SKESA
496
PGLII
501
ATGSV
506
GKNLA
511
SKTNV
516
YISSS
521
AGARW
526
REALP
531
GPHYY
536
TWGDH
541
GGIIT
546
AIAQG
551
METNE
556
LKYST
561
NEGET
566
WKTFI
571
FSEKP
576
VFVYG
581
LLTEP
586
GEKST
591
VFTIF
596
GSNKE
601
NVHSW
606
LILQV
611
NATDA
616
LGVPC
621
TENDY
626
KLWSP
631
SDERG
636
NECLL
641
GHKTV
646
FKRRT
651
PHATC
656
FNGED
661
FDRPV
666
VVSNC
671
SCTRE
676
DYECD
681
FGFKM
686
SEDLS
691
LEVCV
696
PDPEF
701
SGKSY
706
SPPVP
711
CPVGS
716
TYRRT
721
RGYRK
726
ISGDT
731
CSGGD
736
VEARL
741
EGELV
746
PCPLA
751
EENEF
756
ILYAV
761
RKSIY
766
RYDLA
771
SGATE
776
QLPLT
781
GLRAA
786
VALDF
791
DYEHN
796
CLYWS
801
DLALD
806
VIQRL
811
CLNGS
816
TGQEV
821
IINSG
826
LETVE
831
ALAFE
836
PLSQL
841
LYWVD
846
AGFKK
851
IEVAN
856
PDGDF
861
RLTIV
866
NSSVL
871
DRPRA
876
LVLVP
881
QEGVM
886
FWTDW
891
GDLKP
896
GIYRS
901
NMDGS
906
AAYHL
911
VSEDV
916
KWPNG
921
ISVDD
926
QWIYW
931
TDAYL
936
ECIER
941
ITFSG
946
QQRSV
951
ILDNL
956
PHPYA
961
IAVFK
966
NEIYW
971
DDWSQ
976
LSIFR
981
ASKYS
986
GSQME
991
ILANQ
996
LTGLM
1001
DMKIF
1006
YKGKN
1011
TGSNA
1016
CVPRP
1021
CSLLC
1026
LPKAN
1031
NSRSC
1036
RCPED
1041
VSSSV
1046
LPSGD
1051
LMCDC
1056
PQGYQ
1061
LKNNT
1066
CVKEE
1071
NTCLR
1076
NQYRC
1081
SNGNC
1086
INSIW
1091
WCDFD
1096
NDCGD
1101
MSDER
1106
NCPTT
1111
ICDLD
1116
TQFRC
1121
QESGT
1126
CIPLS
1131
YKCDL
1136
EDDCG
1141
DNSDE
1146
SHCEM
1151
HQCRS
1156
DEYNC
1161
SSGMC
1166
IRSSW
1171
VCDGD
1176
NDCRD
1181
WSDEA
1186
NCTAI
1191
YHTCE
1196
ASNFQ
1201
CRNGH
1206
CIPQR
1211
WACDG
1216
DTDCQ
1221
DGSDE
1226
DPVNC
1231
EKKCN
1236
GFRCP
1241
NGTCI
1246
PSSKH
1251
CDGLR
1256
DCSDG
1261
SDEQH
1266
CEPLC
1271
THFMD
1276
FVCKN
1281
RQQCL
1286
FHSMV
1291
CDGII
1296
QCRDG
1301
SDEDA
1306
AFAGC
1311
SQDPE
1316
FHKVC
1321
DEFGF
1326
QCQNG
1331
VCISL
1336
IWKCD
1341
GMDDC
1346
GDYSD
1351
EANCE
1356
NPTEA
1361
PNCSR
1366
YFQFR
1371
CENGH
1376
CIPNR
1381
WKCDR
1386
ENDCG
1391
DWSDE
1396
KDCGD
1401
SHILP
1406
FSTPG
1411
PSTCL
1416
PNYYR
1421
CSSGT
1426
CVMDT
1431
WVCDG
1436
YRDCA
1441
DGSDE
1446
EACPL
1451
LANVT
1456
AASTP
1461
TQLGR
1466
CDRFE
1471
FECHQ
1476
PKTCI
1481
PNWKR
1486
CDGHQ
1491
DCQDG
1496
RDEAN
1501
CPTHS
1506
TLTCM
1511
SREFQ
1516
CEDGE
1521
ACIVL
1526
SERCD
1531
GFLDC
1536
SDESD
1541
EKACS
1546
DELTV
1551
YKVQN
1556
LQWTA
1561
DFSGD
1566
VTLTW
1571
MRPKK
1576
MPSAS
1581
CVYNV
1586
YYRVV
1591
GESIW
1596
KTLET
1601
HSNKT
1606
NTVLK
1611
VLKPD
1616
TTYQV
1621
KVQVQ
1626
CLSKA
1631
HNTND
1636
FVTLR
1641
TPEGL
1646
PDAPR
1651
NLQLS
1656
LPREA
1661
EGVIV
1666
GHWAP
1671
PIHTH
1676
GLIRE
1681
YIVEY
1686
SRSGS
1691
KMWAS
1696
QRAAS
1701
NFTEI
1706
KNLLV
1711
NTLYT
1716
VRVAA
1721
VTSRG
1726
IGNWS
1731
DSKSI
1736
TTIKG
1741
KVIPP
1746
PDIHI
1751
DSYGE
1756
NYLSF
1761
TLTME
1766
SDIKV
1771
NGYVV
1776
NLFWA
1781
FDTHK
1786
QERRT
1791
LNFRG
1796
SILSH
1801
KVGNL
1806
TAHTS
1811
YEISA
1816
WAKTD
1821
LGDSP
1826
LAFEH
1831
VMTRG
1836
VRPPA
1841
PSLKA
1846
KAINQ
1851
TAVEC
1856
TWTGP
1861
RNVVY
1866
GIFYA
1871
TSFLD
1876
LYRNP
1881
KSLTT
1886
SLHNK
1891
TVIVS
1896
KDEQY
1901
LFLVR
1906
VVVPY
1911
QGPSS
1916
DYVVV
1921
KMIPD
1926
SRLPP
1931
RHLHV
1936
VHTGK
1941
TSVVI
1946
KWESP
1951
YDSPD
1956
QDLLY
1961
AIAVK
1966
DLIRK
1971
TDRSY
1976
KVKSR
1981
NSTVE
1986
YTLNK
1991
LEPGG
1996
KYHII
2001
VQLGN
2006
MSKDS
2011
SIKIT
2016
TVSLS
2021
APDAL
2026
KIITE
2031
NDHVL
2036
LFWKS
2041
LALKE
2046
KHFNE
2051
SRGYE
2056
IHMFD
2061
SAMNI
2066
TAYLG
2071
NTTDN
2076
FFKIS
2081
NLKMG
2086
HNYTF
2091
TVQAR
2096
CLFGN
2101
QICGE
2106
PAILL
2111
YDELG
2116
SGADA
2121
SATQA
2126
ARSTD
2131
VAAVV
2136
VPILF
2141
LILLS
2146
LGVGF
2151
AILYT
2156
KHRRL
2161
QSSFT
2166
AFANS
2171
HYSSR
2176
LGSAI
2181
FSSGD
2186
DLGED
2191
DEDAP
2196
MITGF
2201
SDDVP
2206
MVIA
2211
Mutation Information
DNA mutation:
None
Peptide Range:
287 ~ 311
Mut AA position:
299 (13 in Wild Type peptide)
Alignment
Wild Type:
"RENQEVILEEVRDFQLRDKYMFATK
||||||||||||.||||||||||||
Mutant:
RENQEVILEEVRNFQLRDKYMFATK"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay