Immunogenicity 12263
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
UBE3B
Transcript ID
uc009zvj.2
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (875 aa)
MFTLS
1
QTSRA
6
WFIDR
11
ARQAR
16
EERLV
21
QKERE
26
RAAVV
31
IQAHV
36
RSFLC
41
RSRLQ
46
RDIRR
51
EIDDF
56
FKADD
61
PESTK
66
RSALC
71
IFKIA
76
RKLLF
81
LFRIK
86
EDNER
91
FEKLC
96
RSILS
101
SMDAE
106
NEPKV
111
WYVSL
116
ACSKD
121
LTLLW
126
IQQIK
131
NILWY
136
CCDFL
141
KQLKP
146
EILQD
151
SRLIT
156
LYLTM
161
LVTFT
166
DTSTW
171
KILRG
176
KGESL
181
RPAMN
186
HICAN
191
IMGHL
196
NQHGF
201
YSVLQ
206
ILLTR
211
GLARP
216
RPCLS
221
KGTLT
226
AAFSL
231
ALRPV
236
IAAQF
241
SDNLI
246
RPFLI
251
HIMSV
256
PALVT
261
HLSTV
266
TPERL
271
TVLES
276
HDMLR
281
KFIIF
286
LRDQD
291
RCRDV
296
CESLE
301
GCHTL
306
CLMGN
311
LLHLG
316
SLSPR
321
VLEEE
326
TDGFV
331
SLLTQ
336
TLCYC
341
RKYVS
346
QKKSN
351
LTHWH
356
PVLGW
361
FSQSV
366
DYGLN
371
ESMHL
376
ITKQL
381
QFLWG
386
VPLIR
391
IFFCD
396
ILSKK
401
LLESQ
406
EPAHA
411
QPASP
416
QNVLP
421
VKSLL
426
KRAFQ
431
KSASV
436
RNILR
441
PVGGK
446
RVDSA
451
EVQKV
456
CNICV
461
LYQTS
466
LTTLT
471
QIRLQ
476
ILTGL
481
TYLDD
486
LLPKL
491
WAFIC
496
ELGPH
501
GGLKL
506
FLECL
511
NNDTE
516
ESKQL
521
LAMLM
526
LFCDC
531
SRHLI
536
TILDD
541
IEVYE
546
EQISF
551
KLEEL
556
VTISS
561
FLNSF
566
VFKMI
571
WDGIV
576
ENAKG
581
ETLEL
586
FQSVH
591
GWLMV
596
LYERD
601
CRRRF
606
TPEDH
611
WLRKD
616
LKPSV
621
LFQEL
626
DRDRK
631
RAQLI
636
LQYIP
641
HVIPH
646
KNRVL
651
LFRTM
656
VTKEK
661
EKLGL
666
VETSS
671
ASPHV
676
THITI
681
RRSRM
686
LEDGY
691
EQLRQ
696
LSQHA
701
MKGVI
706
RVKFV
711
NDLGV
716
DEAGI
721
DQDGV
726
FKEFL
731
EEIIK
736
RVFDP
741
ALNLF
746
KTTSG
751
DERLY
756
PSPTS
761
YIHEN
766
YLQLF
771
EFVGK
776
MLGKA
781
VYEGI
786
VVDVP
791
FASFF
796
LSQLL
801
GHHHS
806
VFYSS
811
VDELP
816
SLDSE
821
FYKNL
826
TSIKR
831
YDGDI
836
TDLGL
841
TLSYD
846
EDVMG
851
QLVCH
856
ELIPG
861
GKTIP
866
VTNEN
871
Mutation Information
DNA mutation:
None
Peptide Range:
408 ~ 432
Mut AA position:
420 (13 in Wild Type peptide)
Alignment
Wild Type:
"ESQEPAHAQPASPQNVLPVKSLLKR
||||||||||||.||||||||||||
Mutant:
ESQEPAHAQPASSQNVLPVKSLLKR"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) UBE3B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay