Immunogenicity 12268

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HECTD4
Transcript ID
uc021reb.1
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (4284 aa)
MGLLL
1
VFPLI
6
QSQSR
11
TDPSL
16
CNITA
21
EVLLN
26
CLRDC
31
QPLSL
36
TKEPA
41
DCLNG
46
IETLL
51
CSWLE
56
ETSDT
61
GRHIP
66
HKQKE
71
NAAAA
76
LVALA
81
CARGS
86
LKTFV
91
HTVHL
96
LQKQT
101
DLGSL
106
PVADV
111
LYRLL
116
LLEGG
121
PGSPS
126
CLLGG
131
KHIVS
136
WGYED
141
MLPAP
146
DSNTG
151
SSSEN
156
KDADL
161
GRCLT
166
ADGLY
171
LYTTN
176
SVGRG
181
VSKLG
186
SGLHG
191
TLRGF
196
VYCRN
201
EELEP
206
GWVAF
211
GSGSL
216
LHRPV
221
SFDNK
226
PHSLF
231
QVIDQ
236
NTLQV
241
CQVVP
246
MPANH
251
LPIGS
256
TMSTV
261
HLSSD
266
GTYFY
271
WIWSP
276
ASLNE
281
KTPKG
286
HSVFM
291
DIFEL
296
VVENG
301
VFVAN
306
PLQER
311
TILMR
316
KEGES
321
AKSIN
326
EMLLS
331
RLSRY
336
RASPS
341
ATLAA
346
LTGST
351
ISNTL
356
KEDQA
361
ANTSC
366
GLPLK
371
MLRKT
376
PIYTC
381
GTYLV
386
MLVPP
391
PGGSG
396
SSATR
401
SLFGG
406
TSGLS
411
SLKIL
416
ASSLV
421
YNISD
426
GQFTS
431
RADLI
436
DAAGS
441
SLGRG
446
ALVPG
451
LGACY
456
DTVNN
461
MLWTC
466
SNDYI
471
DQWCN
476
PGNQA
481
FHYVC
486
QRLGV
491
SHIIT
496
EPKEE
501
AITTN
506
EVINQ
511
LLHHV
516
GAMCI
521
HQLNL
526
LATNP
531
NLPIT
536
SVLGK
541
QHPIE
546
AHHLS
551
SICDI
556
MEKAM
561
VNGDT
566
CIIRC
571
ILVVF
576
QVVFK
581
FFFSP
586
QTERN
591
RDIIR
596
RSGLL
601
LWQLL
606
MAPKD
611
QICPE
616
IQKEV
621
CLAIS
626
SGLNI
631
LYPGE
636
TEINN
641
LLKLV
646
LTEGE
651
RNSGL
656
SQLRD
661
VILTN
666
LAEQL
671
QNNRF
676
GSDED
681
DHYRL
686
NDELL
691
HYILK
696
IVVRE
701
SCILI
706
TKCQT
711
VSKDD
716
FQKLL
721
STVPA
726
ASSCL
731
RYLMA
736
VQNHL
741
LSNTI
746
LIKPD
751
ENDDS
756
DSSLQ
761
GETLK
766
VQELK
771
VSILA
776
LATQI
781
LTGCD
786
EVLEM
791
LQQVT
796
TALIN
801
SDIAD
806
REQRL
811
KGLEQ
816
VTKAT
821
MLGHL
826
LPVLL
831
TSLMH
836
PNLQT
841
LIMAD
846
ALMPQ
851
LVQLV
856
LYTSQ
861
TALLL
866
KTQCP
871
VFAEV
876
GCSPC
881
GAPDQ
886
KCRLF
891
PDERM
896
LEEKE
901
EPGFL
906
TGLKI
911
PAPWA
916
AGKTV
921
ETVHP
926
VRDNY
931
KFKET
936
VHIPG
941
ARCLY
946
LRFDS
951
RCSSQ
956
YDYDK
961
LVIYA
966
GPNTN
971
SRKVA
976
EYGGN
981
TLGYG
986
SRSVL
991
GTGWP
996
KDLVK
1001
CISPP
1006
SLNFK
1011
VEGDT
1016
VTFSF
1021
EMRSG
1026
REHNT
1031
PDKAM
1036
WGFAC
1041
TVRAQ
1046
ESSED
1051
VSGGL
1056
PFLVD
1061
LALGL
1066
SVLAC
1071
SMLRI
1076
LYNGP
1081
EITKE
1086
EEACQ
1091
ELLRS
1096
KLLQR
1101
CQWQV
1106
EANGV
1111
ISPAL
1116
TPSPS
1121
PLPLT
1126
IEEDR
1131
EFTYP
1136
SDVLV
1141
PPVGN
1146
YFDLP
1151
RIRLP
1156
PGIMI
1161
KLREI
1166
SGRAR
1171
PQFRP
1176
SIKEV
1181
IQPDV
1186
MEEMV
1191
VSCVI
1196
KHLNL
1201
VDALQ
1206
SLINF
1211
QYQEE
1216
HAEEY
1221
DLLCK
1226
IMGET
1231
FKKLN
1236
AMERQ
1241
LQSVA
1246
ELEQK
1251
WQSEV
1256
DDAMQ
1261
GKLEN
1266
NMPFF
1271
YDYHF
1276
NENKM
1281
KELEL
1286
LCSMK
1291
EVSFD
1296
GNDLE
1301
NMVLS
1306
LREKF
1311
LQEVN
1316
SLIQK
1321
PSHPL
1326
AKTKT
1331
LVKSL
1336
MNRAE
1341
LLLHV
1346
TIAAQ
1351
SGLTR
1356
SISGT
1361
PAETP
1366
ACKSA
1371
SETKV
1376
ISHAV
1381
RQPVF
1386
LRSMS
1391
APSDL
1396
EMIGN
1401
EDLEF
1406
TRANQ
1411
RRRHV
1416
TSHRS
1421
SSFTL
1426
LQSLA
1431
IEDSR
1436
DKPTY
1441
SVLLG
1446
QLFAF
1451
IGTNP
1456
DQAVS
1461
SSSFL
1466
LAAQT
1471
RWRRG
1476
NTRKQ
1481
ALVHM
1486
RELLT
1491
AAVRV
1496
GGVTH
1501
LVGPV
1506
TMVLQ
1511
GGPRI
1516
EELTC
1521
GGMVE
1526
QVQEA
1531
FGETM
1536
TSVVS
1541
LCARY
1546
PIACA
1551
NSIGL
1556
LCTIP
1561
YTRSE
1566
EKCLV
1571
RSGLV
1576
QLMDR
1581
LCSLS
1586
NQTES
1591
SSSEK
1596
QTKKQ
1601
KVATM
1606
AWAAF
1611
QVLAN
1616
RCVEW
1621
EKEEG
1626
GSTEA
1631
VHSGL
1636
ARQVS
1641
SLLTN
1646
HLARA
1651
TECCG
1656
NQAAG
1661
NDALQ
1666
DVLSL
1671
LNDLS
1676
RSHIG
1681
KAILS
1686
QPACV
1691
SKLLS
1696
LLLDQ
1701
RPSPK
1706
LVLII
1711
LQLCR
1716
AALPL
1721
MSVED
1726
CGNVE
1731
LPPWS
1736
YSVPS
1741
LNSEQ
1746
EDPSD
1751
PASKI
1756
ASLLL
1761
AKLAD
1766
YVVPG
1771
CQTVL
1776
SPTAS
1781
EPDTT
1786
LTKTS
1791
PKNSL
1796
KGDKD
1801
PGEES
1806
EAVDG
1811
KLSIF
1816
IHKRE
1821
DQSSH
1826
EVLQP
1831
LLSSS
1836
EGRPF
1841
RLGTG
1846
ANMEK
1851
VVKMD
1856
RDMTK
1861
GGCCE
1866
VITEE
1871
AAAAL
1876
RKATK
1881
WAQSG
1886
LIVSI
1891
GPPVE
1896
SINPE
1901
TVSGL
1906
STGDK
1911
KKTAQ
1916
TSICR
1921
ERNSE
1926
LARTD
1931
PVRPF
1936
ISGHV
1941
ANSMA
1946
AEVIA
1951
LLHSL
1956
LMAPE
1961
SNAAQ
1966
IWTTT
1971
AEKVL
1976
SRALM
1981
YIPQL
1986
GKYAE
1991
SILEN
1996
GSSSG
2001
RKLAK
2006
LQRIA
2011
RQAVA
2016
ALCAL
2021
GGFKE
2026
TIKIG
2031
SEVQV
2036
LGRGI
2041
SGSIG
2046
VVASI
2051
NEQEG
2056
IATVR
2061
FPPID
2066
CRKTS
2071
QASDT
2076
LTIPL
2081
SRLCV
2086
PRSEA
2091
LPLHK
2096
LSITE
2101
KVVQA
2106
VQSML
2111
LPQEG
2116
SLSIH
2121
TSLPA
2126
TGDGS
2131
APVMA
2136
VVRLL
2141
AEIRT
2146
RACLV
2151
MAQLL
2156
EDSLF
2161
CEEFI
2166
QQCPA
2171
AVEVL
2176
NLVAQ
2181
ECSAG
2186
ERLAV
2191
VEVQC
2196
ERLRM
2201
LYRDC
2206
ARPPP
2211
PPLQA
2216
DRRQP
2221
KEITW
2226
SPSRV
2231
FPPVR
2236
ACMFS
2241
SHLTS
2246
VTFLA
2251
DPSAG
2256
GGLPR
2261
GTFIY
2266
ATSPL
2271
PVQAP
2276
SFYWE
2281
IEIVS
2286
YGDTD
2291
DDTGP
2296
IVSFG
2301
FTTEA
2306
EKRDG
2311
AWTNP
2316
VGTCL
2321
FHNNG
2326
RAVHY
2331
NGSSL
2336
LQWKS
2341
VRLDV
2346
TLSPG
2351
DVAGI
2356
GWERT
2361
EGTPP
2366
PPGQP
2371
AKGRV
2376
YFTYC
2381
GQRLS
2386
PYLED
2391
VSGGM
2396
WPVVH
2401
IQKKN
2406
TKTRA
2411
NFGSR
2416
PFAYA
2421
EGQAH
2426
RNAAD
2431
LCTDL
2436
AEEIS
2441
ANFEA
2446
LPFAM
2451
ASDSD
2456
NDAGT
2461
SIASD
2466
PGTHG
2471
PPCRI
2476
AAVAT
2481
AQQQY
2486
DSDTS
2491
CHYKV
2496
ELSYE
2501
NFITS
2506
GPDPH
2511
PPPIA
2516
DDESD
2521
DDDDD
2526
DIPQE
2531
DHYAL
2536
LVKAW
2541
ETKVF
2546
PTIRR
2551
RFRNE
2556
AERKS
2561
GLDQI
2566
KGALQ
2571
LGMVD
2576
IARQT
2581
VEFLY
2586
EENGG
2591
IPRDL
2596
YLPTI
2601
EDIKD
2606
EANKF
2611
TIDKV
2616
RKGLT
2621
VVTRS
2626
PDSNN
2631
VASSA
2636
VGTAL
2641
PKFAI
2646
RGMLK
2651
TFGLH
2656
GVVLD
2661
VDSVN
2666
ELVQV
2671
ETYLR
2676
SEGVL
2681
VRYWY
2686
PIDML
2691
ERPPA
2696
GYRRT
2701
ATNGL
2706
VTLDN
2711
TNLQI
2716
HRELL
2721
RCEAA
2726
LARLY
2731
CRMAL
2736
LNIFA
2741
PKLPH
2746
LFTRL
2751
FHIPA
2756
IRDIT
2761
LEHLQ
2766
LLSNQ
2771
LLAPP
2776
LPDGT
2781
ISSSS
2786
ILLAQ
2791
SLQHC
2796
IHSQN
2801
CSATD
2806
LFYQG
2811
NSQTV
2816
REWLN
2821
VAITR
2826
TLHQG
2831
EESLL
2836
ELTKQ
2841
ICSFL
2846
QTAPE
2851
QFPSE
2856
EFPIS
2861
ESKVN
2866
MDVNF
2871
PGAAF
2876
VVVSC
2881
KESQS
2886
GFRKD
2891
SSLYK
2896
APWAR
2901
VLVYG
2906
LGHKV
2911
KRNGQ
2916
LNLIE
2921
AACYP
2926
RDASP
2931
ANTGL
2936
APPPT
2941
ADQYP
2946
SVVLS
2951
TDRVH
2956
IKLGV
2961
SPPPG
2966
AVLVL
2971
HSLPL
2976
EFPLA
2981
MAFAE
2986
QLLSW
2991
KSEDS
2996
EGKSE
3001
DEPDT
3006
IPTSV
3011
LLQVV
3016
ELLGN
3021
FLWTT
3026
DMAAC
3031
VKELV
3036
FHLLA
3041
ELLRT
3046
VHTLE
3051
QRRHP
3056
AGLSS
3061
SIALQ
3066
LNPCL
3071
AMLMA
3076
LQSEL
3081
HKLYD
3086
EETQN
3091
WVSGG
3096
ACGGS
3101
GGAAA
3106
GDQGR
3111
FSTYF
3116
HALME
3121
GCLAV
3126
AEVTL
3131
PTNMS
3136
VTASG
3141
VTSAT
3146
APNLS
3151
DSSSS
3156
SSSSP
3161
GQTPQ
3166
SPSLL
3171
SKRKK
3176
VKMKR
3181
EKASS
3186
SGKRQ
3191
SSRTV
3196
DSDPT
3201
VLSIG
3206
GSKPE
3211
DMLWF
3216
HRALT
3221
LLIIL
3226
RHLTR
3231
KDPQG
3236
LGVTS
3241
DAIAD
3246
ACQAL
3251
VGPTA
3256
HSRLL
3261
VISGI
3266
PTHLD
3271
EGVVR
3276
GAIRK
3281
ACNAH
3286
GGVFK
3291
DEIYI
3296
PLQEE
3301
DTKKP
3306
KDKAE
3311
GGDGK
3316
VEPEK
3321
TLAFP
3326
GTDSM
3331
EVSTS
3336
SSLTP
3341
AMSIS
3346
ASAST
3351
SQASI
3356
CSSQG
3361
ISQTV
3366
SDLSV
3371
DPLPA
3376
GLELP
3381
IPPGL
3386
LEPHA
3391
VSSQE
3396
SLDIS
3401
LCSTG
3406
SLGSL
3411
GSLGE
3416
PLDNA
3421
ETASV
3426
SDMGS
3431
MYTVT
3436
SLDNQ
3441
PLAAR
3446
PIKGF
3451
AVVEI
3456
RSRAK
3461
IEKIR
3466
ASLFN
3471
NNDLI
3476
GLSSL
3481
DGEDE
3486
LMEMS
3491
TEEIL
3496
TVSVV
3501
NQSLF
3506
DTQGS
3511
PGLED
3516
YFNDK
3521
SIKGE
3526
KLVPG
3531
AREVL
3536
TEIFK
3541
SCAHS
3546
EQTLS
3551
LTPAK
3556
PIRVS
3561
DIYLS
3566
KEQIN
3571
SQTPG
3576
NLLHL
3581
FFTNV
3586
RPPKK
3591
VLEDQ
3596
LTQIL
3601
RKYGV
3606
PKPKF
3611
DKSKY
3616
SKAGK
3621
EQHPV
3626
KVVST
3631
KRPIT
3636
KPPAK
3641
DKAVL
3646
NSVSR
3651
TALSE
3656
KKPTV
3661
KPKSP
3666
EKSKP
3671
DEKDP
3676
EKSPT
3681
KKQEV
3686
PEEKY
3691
LTLEG
3696
FHKFV
3701
IDRAR
3706
QDIRS
3711
VWRAI
3716
LSCGY
3721
DLHFE
3726
RCACI
3731
DVRHA
3736
QKASR
3741
KWTLE
3746
MDVAL
3751
VQYIN
3756
QLCRH
3761
LAITP
3766
ARLHP
3771
HEVYL
3776
DPADA
3781
ADPRV
3786
ACLLN
3791
VPIES
3796
LRLRF
3801
ALLQS
3806
LNTTL
3811
ETFFL
3816
PLVEL
3821
RQTPM
3826
YTHSI
3831
AALLK
3836
EAKGL
3841
IFYDT
3846
KVTVM
3851
NRVLN
3856
ATVQR
3861
TADHA
3866
APEIT
3871
LDPLE
3876
IVGGE
3881
IRASE
3886
NSYFC
3891
QAARQ
3896
LASVP
3901
SSQLC
3906
VKLAS
3911
GGDPT
3916
YAFNI
3921
RFTGE
3926
EVHGT
3931
SGSFR
3936
HFLWQ
3941
VCKEL
3946
QSSSL
3951
SLLLL
3956
CPSSA
3961
VNKNK
3966
GKYIL
3971
TPSPI
3976
TYGEE
3981
QLLHF
3986
LGQLL
3991
GIAIR
3996
ADVPL
4001
PLDLL
4006
PSFWK
4011
TLVGE
4016
PLDPE
4021
QDLQE
4026
ADILT
4031
YNYVK
4036
KFESI
4041
NDETE
4046
LEALC
4051
AEIAS
4056
QHLAT
4061
ESPDS
4066
PNKPC
4071
CRFTY
4076
LTMTG
4081
EEVEL
4086
CSRGR
4091
HILVA
4096
WENKD
4101
IYAAA
4106
IRSLR
4111
LRELQ
4116
NVECV
4121
TAVRA
4126
GLGSI
4131
IPLQL
4136
LTMLS
4141
PLEME
4146
LRTCG
4151
LPYIN
4156
LEFLK
4161
AHTMY
4166
QVGLM
4171
ETDQH
4176
IEFFW
4181
GALEM
4186
FTQEE
4191
LCKFI
4196
KFACN
4201
QERIP
4206
FTCPC
4211
KDGGP
4216
DTAHV
4221
PPYPM
4226
KIAPP
4231
DGTAG
4236
SPDSR
4241
YIRVE
4246
TCMFM
4251
IKLPQ
4256
YSSLE
4261
IMLEK
4266
LRCAI
4271
HYRED
4276
PLSG
4281
Mutation Information
DNA mutation:
None
Peptide Range:
2864 ~ 2888
Mut AA position:
2876 (13 in Wild Type peptide)
Alignment
Wild Type:
"ISESKVNMDVNFPGAAFVVVSCKES
||||||||||||.||||||||||||
Mutant:
ISESKVNMDVNFSGAAFVVVSCKES"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay