Immunogenicity 12307

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
FRY
Transcript ID
uc001utx.3
HLA INFO
C*02:02
TCR INFO

No TCR info found!

T cell Tumor cell C*02:02
sequence
Full length protein sequence (3013 aa)
MASQQ
1
DSGFF
6
EISIK
11
YLLKS
16
WSNTS
21
PVGNG
26
YIKPP
31
VPPAS
36
GTHRE
41
KGPPT
46
MLPIN
51
VDPDS
56
KPGEY
61
VLKSL
66
FVNFT
71
TQAER
76
KIRII
81
MAEPL
86
EKPLT
91
KSLQR
96
GEDPQ
101
FDQVI
106
SSMSS
111
LSEYC
116
LPSIL
121
RTLFD
126
WYKRQ
131
NGIED
136
ESHEY
141
RPRTS
146
NKSKS
151
DEQQR
156
DYLME
161
RRDLA
166
IDFIF
171
SLVLI
176
EVLKQ
181
IPLHP
186
VIDSL
191
IHDVI
196
NLAFK
201
HFKYK
206
EGYLG
211
PNTGN
216
MHIVA
221
DLYAE
226
VIGVL
231
AQAKF
236
PAVKK
241
KFMAE
246
LKELR
251
HKEQN
256
PYVVQ
261
SIISL
266
IMGMK
271
FFRIK
276
MYPVE
281
DFEAS
286
LQFMQ
291
ECAHY
296
FLEVK
301
DKDIK
306
HALAG
311
LFVEI
316
LVPVA
321
AAVKN
326
EVNVP
331
CLRNF
336
VESLY
341
DTTLE
346
LSSRK
351
KHSLA
356
LYPLV
361
TCLLC
366
VSQKQ
371
LFLNR
376
WHIFL
381
NNCLS
386
NLKNK
391
DPKMA
396
RVALE
401
SLYRL
406
LWVYM
411
IRIKC
416
ESNTA
421
TQSRL
426
ITIIT
431
TLFPK
436
GSRGV
441
VPRDM
446
PLNIF
451
VKIIQ
456
FIAQE
461
RLDFA
466
MKEII
471
FDFLC
476
VGKPA
481
KAFSL
486
NPERM
491
NIGLR
496
AFLVI
501
ADSLQ
506
QKDGE
511
PPMPV
516
TGAVL
521
PSGNT
526
LRVKK
531
TYLSK
536
TLTEE
541
EAKMI
546
GMSLY
551
YSQVR
556
KAVDN
561
ILRHL
566
DKEVG
571
RCMML
576
TNVQM
581
LNKEP
586
EDMIT
591
GERKP
596
KIDLF
601
RTCVA
606
AIPRL
611
LPDGM
616
SKLEL
621
IDLLA
626
RLSIH
631
MDDEL
636
RHIAQ
641
NSLQG
646
LLVDF
651
SDWRE
656
DVLFG
661
FTNFL
666
LREVN
671
DMHHT
676
LLDSS
681
LKLLL
686
QLLTQ
691
WKLVI
696
QTQGK
701
VYEQA
706
NKIRN
711
SELIA
716
NGSSH
721
RIQSE
726
RGPHC
731
SVLHA
736
VEGFA
741
LVLLC
746
SFQVA
751
TRKLS
756
VLILK
761
EIRAL
766
FIALG
771
QPEDD
776
DRPMI
781
DVMDQ
786
LSSSI
791
LESFI
796
HVAVS
801
DSATL
806
PLTHN
811
VDLQW
816
LVEWN
821
AVLVN
826
SHYDV
831
KSPSH
836
VWIFA
841
QSVKD
846
PWVLC
851
LFSFL
856
RQENL
861
PKHCP
866
TALSY
871
AWPYA
876
FTRLQ
881
SVMPL
886
VDPNS
891
PINAK
896
KTSTA
901
GSGDN
906
YVTLW
911
RNYLI
916
LCFGV
921
AKPSI
926
MSPGH
931
LRAST
936
PEIMA
941
TTPDG
946
TVSYD
951
NKAIG
956
TPSVG
961
VLLKQ
966
LVPLM
971
RLESI
976
EITES
981
LVLGF
986
GRTNS
991
LVFRE
996
LVEEL
1001
HPLMK
1006
EALER
1011
RPENK
1016
KRRER
1021
RDLLR
1026
LQLLR
1031
IFELL
1036
ADAGV
1041
ISDST
1046
NGALE
1051
RDTLA
1056
LGALF
1061
LEYVD
1066
LTRML
1071
LEAEN
1076
DKEVE
1081
ILKDI
1086
RAHFS
1091
AMVAN
1096
LIQCV
1101
PVHHR
1106
RFLFP
1111
QQSLR
1116
HHLFI
1121
LFSQW
1126
AGPFS
1131
IMFTP
1136
LDRYS
1141
DRNHQ
1146
ITRYQ
1151
YCALK
1156
AMSAV
1161
LCCGP
1166
VFDNV
1171
GLSPD
1176
GYLYK
1181
WLDNI
1186
LACQD
1191
LRVHQ
1196
LGCEV
1201
VVLLL
1206
ELNPD
1211
QINLF
1216
NWAID
1221
RCYTG
1226
SYQLA
1231
SGCFK
1236
AIATV
1241
CGSRN
1246
YPFDI
1251
VTLLN
1256
LVLFK
1261
ASDTN
1266
REIYE
1271
ISMQL
1276
MQILE
1281
AKLFV
1286
YSKKV
1291
AEQRP
1296
GSILY
1301
GTHGP
1306
LPPLY
1311
SVSLA
1316
LLSCE
1321
LARMY
1326
PELTL
1331
PLFSE
1336
VSQRF
1341
PTTHP
1346
NGRQI
1351
MLTYL
1356
LPWLH
1361
NIELV
1366
DSRLL
1371
LPGSS
1376
PSSPE
1381
DEVKD
1386
REGDV
1391
TASHG
1396
LRGNG
1401
WGSPE
1406
ATSLV
1411
LNNLM
1416
YMTAK
1421
YGDEV
1426
PGPEM
1431
ENAWN
1436
ALANN
1441
EKWSN
1446
NLRIT
1451
LQFLI
1456
SLCGV
1461
SSDTV
1466
LLPYI
1471
KKVAI
1476
YLCRN
1481
NTIQT
1486
MEELL
1491
FELQQ
1496
TEPVN
1501
PIVQH
1506
CDNPP
1511
FYRFT
1516
ASSKA
1521
SAAAS
1526
GTTSS
1531
SNTVV
1536
AGQEN
1541
FPDAE
1546
ENKIL
1551
KESDE
1556
RFSNV
1561
IRAHT
1566
RLESR
1571
YSNSS
1576
GGSYD
1581
EDKND
1586
PISPY
1591
TGWLL
1596
TITET
1601
KQPQP
1606
LPMPC
1611
TGGCW
1616
APLVD
1621
YLPET
1626
ITPRG
1631
PLHRC
1636
NIAVI
1641
FMTEM
1646
VVDHS
1651
VREDW
1656
ALHLP
1661
LLLHA
1666
VFLGL
1671
DHYRP
1676
EVFEH
1681
SKKLL
1686
LHLLI
1691
ALSCN
1696
SNFHS
1701
IASVL
1706
LQTRE
1711
MGEAK
1716
TLTVQ
1721
PAYQP
1726
EYLYT
1731
GGFDF
1736
LREDQ
1741
SSPVP
1746
DSGLS
1751
SSSTS
1756
SSISL
1761
GGSSG
1766
NLPQM
1771
TQEVE
1776
DVDTA
1781
AETDE
1786
KANKL
1791
IEFLT
1796
TRAFG
1801
PLWCH
1806
EDITP
1811
KNQNS
1816
KSAEQ
1821
LTNFL
1826
RHVVS
1831
VFKDS
1836
KSGFH
1841
LEHQL
1846
SEVAL
1851
QTALA
1856
SSSRH
1861
YAGRS
1866
FQIFR
1871
ALKQP
1876
LSAHA
1881
LSDLL
1886
SRLVE
1891
VIGEH
1896
GDEIQ
1901
GYVME
1906
ALLTL
1911
EAAVD
1916
NLSDC
1921
LKNSD
1926
LLTVL
1931
SRSSS
1936
PDLSS
1941
SSKLT
1946
ASRKS
1951
TGQLN
1956
MNPGT
1961
TSGNT
1966
ATAER
1971
SRHQR
1976
SFSVP
1981
KKFGV
1986
IDRSS
1991
DPPRS
1996
ATLDR
2001
IQACT
2006
QQGLS
2011
SKTRS
2016
SSSLK
2021
DSLTD
2026
PSHIN
2031
HPTNL
2036
LATIF
2041
WVTVA
2046
LMESD
2051
FEFEY
2056
LMALR
2061
LLSRL
2066
LAHMP
2071
LDKAE
2076
NREKL
2081
EKLQA
2086
QLKWA
2091
DFSGL
2096
QQLLL
2101
KGFTS
2106
LTTTD
2111
LTLQL
2116
FSLLT
2121
PVSKI
2126
SMVDA
2131
SHAIG
2136
FPLNV
2141
LCLLP
2146
QLIQH
2151
FENPN
2156
QFCKD
2161
IAERI
2166
AQVCL
2171
EEKNP
2176
KLSNL
2181
AHVMT
2186
LYKTH
2191
SYTRD
2196
CATWV
2201
NVVCR
2206
YLHEA
2211
YADIT
2216
LNMVT
2221
YLAEL
2226
LEKGL
2231
PSVQQ
2236
PLLQV
2241
IYSLL
2246
SYMDL
2251
SVVPV
2256
KQFNV
2261
EVLKT
2266
IEKYV
2271
QSVHW
2276
REALN
2281
ILKLV
2286
VSRSA
2291
SLVLP
2296
SYQHS
2301
DLSKI
2306
EIHRV
2311
WTSAS
2316
KELPG
2321
KTLDF
2326
HFDIS
2331
ETPII
2336
GRRYD
2341
ELQNS
2346
SGRDG
2351
KPRAM
2356
AVTRS
2361
TSSTS
2366
SGSNS
2371
NVLVP
2376
VSWKR
2381
PQYSQ
2386
KRTKE
2391
KLVHV
2396
LSLCG
2401
QEVGL
2406
SKNPS
2411
VIFSS
2416
CGDLD
2421
LLEHQ
2426
TSLVS
2431
SEDGA
2436
REQEN
2441
MDDTN
2446
SEQQF
2451
RVFRD
2456
FDFLD
2461
VELED
2466
GEGES
2471
MDNFN
2476
WGVRR
2481
RSLDS
2486
LDKCD
2491
MQILE
2496
ERQLS
2501
GSTPS
2506
LNKMH
2511
HEDSD
2516
ESSEE
2521
EDLTA
2526
SQILE
2531
HSDLI
2536
MTLSP
2541
SEETN
2546
PMELL
2551
TTACD
2556
STPAE
2561
PHSFN
2566
TRMSS
2571
FDASL
2576
PDMNN
2581
LQISE
2586
GSKAE
2591
AVREE
2596
EDTTV
2601
HEDDL
2606
SSSIN
2611
ELPAA
2616
FECSD
2621
SFSLD
2626
MTEGE
2631
EKGNR
2636
ALDQF
2641
TLASF
2646
GEGDR
2651
GVSPP
2656
PSPFF
2661
SAILA
2666
AFQPA
2671
ACDDA
2676
EEAWR
2681
SHINQ
2686
LMCDS
2691
DGSCA
2696
VYTFH
2701
VFSSL
2706
FKNIQ
2711
KRFCF
2716
LTCDA
2721
ASYLG
2726
DNLRG
2731
IGSKF
2736
VSSSQ
2741
MLTSC
2746
SECPT
2751
LFVDA
2756
ETLLS
2761
CGLLD
2766
KLKFS
2771
VLELQ
2776
EYLDT
2781
YNNRK
2786
EATLS
2791
WLANC
2796
KATFA
2801
GGSRD
2806
GVITC
2811
QPGDS
2816
EEKQL
2821
ELCQR
2826
LYKLH
2831
FQLLL
2836
LFQSY
2841
CKLIG
2846
QVHEV
2851
SSMPE
2856
LLNMS
2861
RELSD
2866
LKKHL
2871
KEASA
2876
VIAAD
2881
PLYSD
2886
GAWSE
2891
PTFTS
2896
TEAAI
2901
QSMLE
2906
CLKNN
2911
ELGKA
2916
LRQIR
2921
ECRSL
2926
WPNDI
2931
FGSSS
2936
DDEVQ
2941
TLLNI
2946
YFRHQ
2951
TLGQT
2956
GTYAL
2961
VGSNQ
2966
SLTEI
2971
CTKLM
2976
ELNME
2981
IRDMI
2986
RRAQS
2991
YRVLT
2996
TFLPD
3001
SSVSG
3006
TSL
3011
Mutation Information
DNA mutation:
None
Peptide Range:
1131 ~ 1155
Mut AA position:
1143 (13 in Wild Type peptide)
Alignment
Wild Type:
"AGPFSIMFTPLDRYSDRNHQITRYQ
||||||||||||.||||||||||||
Mutant:
AGPFSIMFTPLDCYSDRNHQITRYQ"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay