Immunogenicity 12330

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HTR2A
Transcript ID
uc010acr.4
HLA INFO
C*03:03
TCR INFO

No TCR info found!

T cell Tumor cell C*03:03
sequence
Full length protein sequence (471 aa)
MDILC
1
EENTS
6
LSSTT
11
NSLMQ
16
LNDDT
21
RLYSN
26
DFNSG
31
EANTS
36
DAFNW
41
TVDSE
46
NRTNL
51
SCEGC
56
LSPSC
61
LSLLH
66
LQEKN
71
WSALL
76
TAVVI
81
ILTIA
86
GNILV
91
IMAVS
96
LEKKL
101
QNATN
106
YFLMS
111
LAIAD
116
MLLGF
121
LVMPV
126
SMLTI
131
LYGYR
136
WPLPS
141
KLCAV
146
WIYLD
151
VLFST
156
ASIMH
161
LCAIS
166
LDRYV
171
AIQNP
176
IHHSR
181
FNSRT
186
KAFLK
191
IIAVW
196
TISVG
201
ISMPI
206
PVFGL
211
QDDSK
216
VFKEG
221
SCLLA
226
DDNFV
231
LIGSF
236
VSFFI
241
PLTIM
246
VITYF
251
LTIKS
256
LQKEA
261
TLCVS
266
DLGTR
271
AKLAS
276
FSFLP
281
QSSLS
286
SEKLF
291
QRSIH
296
REPGS
301
YTGRR
306
TMQSI
311
SNEQK
316
ACKVL
321
GIVFF
326
LFVVM
331
WCPFF
336
ITNIM
341
AVICK
346
ESCNE
351
DVIGA
356
LLNVF
361
VWIGY
366
LSSAV
371
NPLVY
376
TLFNK
381
TYRSA
386
FSRYI
391
QCQYK
396
ENKKP
401
LQLIL
406
VNTIP
411
ALAYK
416
SSQLQ
421
MGQKK
426
NSKQD
431
AKTTD
436
NDCSM
441
VALGK
446
QHSEE
451
ASKDN
456
SDGVN
461
EKVSC
466
V
471
Mutation Information
DNA mutation:
None
Peptide Range:
393 ~ 417
Mut AA position:
405 (13 in Wild Type peptide)
Alignment
Wild Type:
"RYIQCQYKENKKPLQLILVNTIPAL
||||||||||||.||||||||||||
Mutant:
RYIQCQYKENKKSLQLILVNTIPAL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay