Immunogenicity 1234

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF208
Transcript ID
ENST00000397126
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*06:03
sequence
Full length protein sequence (1280 aa)
MGSLT
1
FRDVA
6
IEFSL
11
EEWQC
16
LDTAQ
21
QNLYR
26
NVMLE
31
NYRNL
36
VFLGI
41
AAFKP
46
DLIIF
51
LEEGK
56
ESWNM
61
KRHEM
66
VEESP
71
VICSH
76
FAQDL
81
WPEQG
86
IEDSF
91
QKVIL
96
RRYEK
101
CGHEN
106
LHLKI
111
GYTNV
116
DECKV
121
HKEGY
126
NKLNQ
131
SLTTT
136
QSKVF
141
QRGKY
146
ANVFH
151
KCSNS
156
NRHKI
161
RHTGK
166
KHLQC
171
KEYVR
176
SFCML
181
SHLSQ
186
HKRIY
191
TRENS
196
YKCEE
201
GGKAF
206
NWSST
211
LTYYK
216
SAHTG
221
EKPYR
226
CKECG
231
KAFSK
236
FSILT
241
KHKVI
246
HTGEK
251
SYKCE
256
ECGKA
261
FNQSA
266
ILTKH
271
KIIHT
276
GEKPN
281
KCEEC
286
GKAFS
291
KVSTL
296
TTHKA
301
IHAGE
306
KPYKC
311
KECGK
316
AFSKV
321
STLIT
326
HKAIH
331
AGEKP
336
YKCKE
341
CGKAF
346
SKFSI
351
LTKHK
356
VIHTG
361
EKPYK
366
CEECG
371
KAYKW
376
PSTLS
381
YHKKI
386
HTGEK
391
PYKCE
396
ECGKG
401
FSMFS
406
ILTKH
411
EVIHT
416
GEKPY
421
KCEEC
426
GKAFN
431
WSSNL
436
MEHKK
441
IHTGE
446
TPYKC
451
EECGK
456
GFSMF
461
SILTK
466
HKVIH
471
NGEKP
476
YKCEE
481
CDKAT
486
HAGEK
491
PYKCE
496
ECGKA
501
FNWSS
506
NLMEH
511
KRIHT
516
GEKPY
521
KCEEC
526
GKSFS
531
TFSIL
536
TKHKV
541
IHTGE
546
KPYKC
551
EECGK
556
AYKWS
561
STLSY
566
HKKIH
571
TVEKP
576
YKCEE
581
CGKAF
586
NQSAI
591
LIKHK
596
RIHTG
601
EKPYK
606
CEECG
611
KTFSK
616
VSTLT
621
THKAI
626
HAGEK
631
PYKCK
636
ECGKT
641
FIKVS
646
TLTTH
651
KAIHA
656
GEKPY
661
KCKEC
666
GKAFS
671
KFSIL
676
TKHKV
681
IHTGE
686
KPYKC
691
EECGK
696
AFNWS
701
SNLME
706
HKRIH
711
TGEKP
716
YKCEE
721
CGKSF
726
STFSV
731
LTKHK
736
VIHTG
741
EKPYK
746
CEECG
751
KAYKW
756
SSTLS
761
YHKKI
766
HTVEK
771
PYKCE
776
ECGKA
781
FNRSA
786
ILIKH
791
KRIHT
796
DEKPY
801
KCEEC
806
GKTFS
811
KVSTL
816
TTHKA
821
IHAGE
826
KPYKC
831
KECGK
836
AFSKF
841
SILTK
846
HKVIH
851
TGEKP
856
YKCEE
861
CGKAY
866
KWPST
871
LSYHK
876
KIHTG
881
EKPYK
886
CEECG
891
KGFSM
896
FSILT
901
KHEVI
906
HTGEK
911
PYKCE
916
ECGKA
921
FSWLS
926
VFSKH
931
KKTHA
936
GEKFY
941
KCEAC
946
GKAYK
951
SSSTL
956
SYHKK
961
IHTEE
966
KPYKY
971
EECGK
976
GFSTF
981
SILTK
986
HKVIH
991
TGEKP
996
YKCEE
1001
CGKAF
1006
NWSSN
1011
LMEHK
1016
KIHTG
1021
ETPYK
1026
CEECD
1031
KAFSW
1036
PSSLT
1041
EHKAT
1046
HAGEK
1051
PYKCE
1056
ECGKA
1061
FSWPS
1066
RLTEH
1071
KATHA
1076
GEEPY
1081
KCEEC
1086
GKAFN
1091
WSSNL
1096
MEHKR
1101
IHTGE
1106
KPYKC
1111
EECGK
1116
SFSTF
1121
SILTK
1126
HKVIH
1131
TGEKP
1136
YKCEE
1141
CGKAY
1146
KWSST
1151
LSYHK
1156
KIHTV
1161
EKPYK
1166
CEECG
1171
KGFVM
1176
FSILA
1181
KHKVI
1186
HTGEK
1191
LYKCE
1196
ECGKA
1201
YKWPS
1206
TLRYH
1211
KKIHT
1216
GEKPY
1221
KCEEC
1226
GKAFS
1231
TFSIL
1236
TKHKV
1241
IHTGE
1246
KPYKC
1251
EECGK
1256
AFSWL
1261
SVFSK
1266
HKKIH
1271
TGEKL
1276
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 25
Mut AA position:
13 (13 in Wild Type peptide)
Alignment
Wild Type:
"MGSLTFRDVAIEFSLEEWQCLDTAQ
||||||||||||.||||||||||||
Mutant:
MGSLTFRDVAIELSLEEWQCLDTAQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF208

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay