Immunogenicity 12379
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
AKAP6
Transcript ID
uc010aml.3
HLA INFO
B*13:02
TCR INFO
No TCR info found!
Full length protein sequence (1072 aa)
MSVTL
1
SPLRS
6
QDLDP
11
MATDA
16
SPMAI
21
NMTPT
26
VEQGE
31
GEEAM
36
KDMDS
41
DQQYE
46
KPPPL
51
HTGAD
56
WKIVL
61
HLPEI
66
ETWLR
71
MTSER
76
VRDLT
81
YSVQQ
86
DSDSK
91
HVDVH
96
LVQLK
101
DICED
106
ISDHV
111
EQIHA
116
LLETE
121
FSLKL
126
LSYSV
131
NVIVD
136
IHAVQ
141
LLWHQ
146
LRVSV
151
LVLRE
156
RILQG
161
LQDAN
166
GNYTR
171
QTDIL
176
QAFSE
181
ETKEG
186
RLDSL
191
TEVDD
196
SGQLT
201
IKCSQ
206
NYLSL
211
DCGIT
216
AFELS
221
DYSPS
226
EDLLS
231
GLGDM
236
TSSQV
241
KTKPF
246
DSWSY
251
SEMEK
256
EFPEL
261
IRSVG
266
LLTVA
271
ADSIS
276
TNGSE
281
AVTEE
286
VSQVS
291
LSVDD
296
KGGCE
301
EDNAS
306
AVEEQ
311
PGLTL
316
GVSSS
321
SGEAL
326
TNAAQ
331
PSSET
336
VQQES
341
SSSSH
346
HDAKN
351
QQPVP
356
CENAT
361
PKRTI
366
RDCFN
371
YNEDS
376
PTQPT
381
LPKRG
386
LFLKE
391
ETFKN
396
DLKGN
401
GGKRQ
406
MVDLK
411
PEMSR
416
STPSL
421
VDPPD
426
RSKLC
431
LVLQS
436
SYPNS
441
PSAAS
446
QSYEC
451
LHKVG
456
NGNLE
461
NTVKF
466
HIKEI
471
SSSLG
476
RLNDC
481
YKEKS
486
RLKKP
491
HKTSE
496
EVPPC
501
RTPKR
506
GTGSG
511
KQAKN
516
TKSSA
521
VPNGE
526
LSYTS
531
KAIEG
536
PQTNS
541
ASTSS
546
LEPCN
551
QRSWN
556
AKLQL
561
QSETS
566
SSPAF
571
TQSSE
576
SSVGS
581
DNIMS
586
PVPLL
591
SKHKS
596
KKGQA
601
SSPSH
606
VTRNG
611
EVVEA
616
WYGSD
621
EYLAL
626
PSHLK
631
QTEVL
636
ALKLE
641
NLTKL
646
LPQKP
651
RGETI
656
QNIDD
661
WELSE
666
MNSDS
671
EIYPT
676
YHVKK
681
KHTRL
686
GRVSP
691
SSSSD
696
IASSL
701
GESIE
706
SGPLS
711
DILSD
716
EESSM
721
PLAGM
726
KKYAD
731
EKSER
736
ASSSE
741
KNESH
746
SATKS
751
ALIQK
756
LMQDI
761
QHQDN
766
YEAIW
771
EKIEG
776
FVNKL
781
DEFIQ
786
WLNEA
791
METTE
796
NWTPP
801
KAEMD
806
DLKLY
811
LETHL
816
SFKLN
821
VDSHC
826
ALKEA
831
VEEEG
836
HQLLE
841
LIASH
846
KAGLK
851
DMLRM
856
IASQW
861
KELQR
866
QIKRQ
871
HSWIL
876
RALDT
881
IKAEI
886
LATDV
891
SVEDE
896
EGTGS
901
PKAEV
906
QLCYL
911
EAQRD
916
AVEQM
921
SLKLY
926
SEQYT
931
SSSKR
936
KEEFA
941
DMSKV
946
HSVGS
951
NGLLD
956
FDSEY
961
QELWD
966
WLIDM
971
ESLVM
976
DSHDL
981
MMSEE
986
QQQHL
991
YKRYS
996
VEMSI
1001
RHLKK
1006
TELLS
1011
KVEAL
1016
KKGGV
1021
LLPND
1026
LLEKV
1031
DSINE
1036
KWELL
1041
GVFAF
1046
LLLFV
1051
GYVYI
1056
FCVVK
1061
YSVRF
1066
LI
1071
Mutation Information
DNA mutation:
None
Peptide Range:
683 ~ 707
Mut AA position:
695 (13 in Wild Type peptide)
Alignment
Wild Type:
"VKKKHTRLGRVSPSSSSDIASSLGE
||||||||||||.||||||||||||
Mutant:
VKKKHTRLGRVSLSSSSDIASSLGE"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) AKAP6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay