Immunogenicity 12458

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS13C
Transcript ID
uc002ahc.2
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (3585 aa)
MVLES
1
VVADL
6
LNRFL
11
GDYVE
16
NLNKS
21
QLKLG
26
IWGGN
31
VALDN
36
LQIKE
41
NALSE
46
LDVPF
51
KVKAG
56
QIDKL
61
TLKIP
66
WKNLY
71
GEAVV
76
ATLEG
81
LYLLV
86
VPGAS
91
IKYDA
96
VKEEK
101
SLQDV
106
KQKEL
111
SRIEE
116
ALQKA
121
AEKDK
126
PKEAK
131
KDTFV
136
EKLAT
141
QVIKN
146
VQVKI
151
TDIHI
156
KYEDD
161
VTDPK
166
RPLSF
171
GVTLG
176
ELSLL
181
TANEH
186
WTPCI
191
LNEAD
196
KIIYK
201
LIRLD
206
SLSAY
211
WNVNC
216
SMSYQ
221
RSREQ
226
ILDQL
231
KNEIL
236
TSGNI
241
PPNYQ
246
YIFQP
251
ISASA
256
KLYMN
261
PYAES
266
ELKTP
271
KLDCN
276
IEIQN
281
IAIEL
286
TKPQY
291
LSMID
296
LLESV
301
DYMVR
306
NAPYR
311
KYKPY
316
LPLHT
321
NGRRW
326
WKYAI
331
DSVLE
336
VHIRR
341
YTQMW
346
SWSNI
351
KKHRQ
356
LLKSY
361
KIAYK
366
NKLTQ
371
SKVSE
376
EIQKE
381
IQDLE
386
KTLDV
391
FNIIL
396
ARQQA
401
QVEVI
406
RSGQK
411
LRKKS
416
ADTGE
421
KRGGW
426
FSGLW
431
GKKES
436
KKKDE
441
ESLIP
446
ETIDD
451
LMTPE
456
EKDKL
461
FTAIG
466
YSEST
471
HNLTL
476
PKQYV
481
AHIMT
486
LKLVS
491
TSVTI
496
RENKN
501
IPEIL
506
KIQII
511
GLGTQ
516
VSQRP
521
GAQAL
526
KVEAK
531
LEHWY
536
ITGLR
541
QQDIV
546
PSLVA
551
SIGDT
556
TSSLL
561
KIKFE
566
TNPED
571
SPADQ
576
TLIVQ
581
SQPVE
586
VIYDA
591
KTVNA
596
VVEFF
601
QSNKG
606
LDLEQ
611
ITSAT
616
LMKLE
621
EIKER
626
TATGL
631
THIIE
636
TRKVL
641
DLRIN
646
LKPSY
651
LVVPQ
656
TGFHH
661
EKSDL
666
LILDF
671
GTFQL
676
NSKDQ
681
GLQKT
686
TNSSL
691
EEIMD
696
KAYDK
701
FDVEI
706
KNVQL
711
LFARA
716
EETWK
721
KCRFQ
726
HPSTM
731
HILQP
736
MDIHV
741
ELAKA
746
MVEKD
751
IRMAR
756
FKVSG
761
GLPLM
766
HVRIS
771
DQKMK
776
DVLYL
781
MNSIP
786
LPQKS
791
SAQSP
796
ERQVS
801
SIPII
806
SGGTK
811
GLLGT
816
SLLLD
821
TVESE
826
SDDEY
831
FDAED
836
GEPQT
841
CKSMK
846
GSELK
851
KAAEV
856
PNEEL
861
INLLL
866
KFEIK
871
EVILE
876
FTKQQ
881
KEEDT
886
ILVFN
891
VTQLG
896
TEATM
901
RTFDL
906
TVVSY
911
LKKIS
916
LDYHE
921
IEGSK
926
RKPLH
931
LISSS
936
DKPGL
941
DLLKV
946
EYIKA
951
DKNGP
956
SFQTA
961
FGKTE
966
QTVKV
971
AFSSL
976
NLLLQ
981
TQALV
986
ASINY
991
LTTII
996
PSDDQ
1001
SISVA
1006
KEVQI
1011
STEKQ
1016
QKNST
1021
LPKAI
1026
VSSRD
1031
SDIID
1036
FRLFA
1041
KLNAF
1046
CVIVC
1051
NEKNN
1056
IAEIK
1061
IQGLD
1066
SSLSL
1071
QSRKQ
1076
SLFAR
1081
LENII
1086
VTDVD
1091
PKTVH
1096
KKAVS
1101
IMGNE
1106
VFRFN
1111
LDLYP
1116
DATEG
1121
DLYTD
1126
MSKVD
1131
GVLSL
1136
NVGCI
1141
QIVYL
1146
HKFLM
1151
SLLNF
1156
LNNFQ
1161
TAKES
1166
LSAAT
1171
AQAAE
1176
RAATS
1181
VKDLA
1186
QRSFR
1191
VSINI
1196
DLKAP
1201
VIVIP
1206
QSSIS
1211
TNAVV
1216
VDLGL
1221
IRVHN
1226
QFSLV
1231
SDEDY
1236
LNPPV
1241
IDRMD
1246
VQLTK
1251
LTLYR
1256
TVIQP
1261
GIYHP
1266
DIQLL
1271
HPINL
1276
EFLVN
1281
RNLAA
1286
SWYHK
1291
VPVVE
1296
IKGHL
1301
DSMNV
1306
SLNQE
1311
DLNLL
1316
FRILT
1321
ENLCE
1326
GTEDL
1331
DKVKP
1336
RVQET
1341
GEIKE
1346
PLEIS
1351
ISQDV
1356
HDSKN
1361
TLTTG
1366
VEEIR
1371
SVDII
1376
NMLLN
1381
FEIKE
1386
VVVTL
1391
MKKSE
1396
KKGRP
1401
LHELN
1406
VLQLG
1411
MEAKV
1416
KTYDM
1421
TAKAY
1426
LKKIS
1431
MQCFD
1436
FTDSK
1441
GEPLH
1446
IINSS
1451
NVTDE
1456
PLLKM
1461
LLTKA
1466
DSDGP
1471
EFKTI
1476
HDSTK
1481
QRLKV
1486
SFASL
1491
DLVLH
1496
LEALL
1501
SFMDF
1506
LSSAA
1511
PFSEP
1516
SSSEK
1521
ESELK
1526
PLVGE
1531
SRSIA
1536
VKAVS
1541
SNISQ
1546
KDVFD
1551
LKITA
1556
ELNAF
1561
NVFVC
1566
DQKCN
1571
IADIK
1576
IHGMD
1581
ASISV
1586
KPKQT
1591
DVFAR
1596
LKDII
1601
VMNVD
1606
LQSIH
1611
KKAVS
1616
ILGDE
1621
VFRFQ
1626
LTLYP
1631
DATEG
1636
EAYAD
1641
MSKVD
1646
GKLSF
1651
KVGCI
1656
QIVYV
1661
HKFFM
1666
SLLNF
1671
LNNFQ
1676
TAKEA
1681
LSTAT
1686
VQAAE
1691
RAASS
1696
MKDLA
1701
QKSFR
1706
LLMDI
1711
NLKAP
1716
VIIIP
1721
QSSVS
1726
PNAVI
1731
ADLGL
1736
IRVEN
1741
KFSLV
1746
PMEHY
1751
SLPPV
1756
IDKMN
1761
IELTQ
1766
LKLSR
1771
TILQA
1776
SLPQN
1781
DIEIL
1786
KPVNM
1791
LLSIQ
1796
RNLAA
1801
AWYVQ
1806
IPGME
1811
IKGKL
1816
KPMQV
1821
ALSED
1826
DLTVL
1831
MKILL
1836
ENLGE
1841
ASSQP
1846
SPTQS
1851
VQETV
1856
RVRKV
1861
DVSSV
1866
PDHLK
1871
EQEDW
1876
TDSKL
1881
SMNQI
1886
VSLQF
1891
DFHFE
1896
SLSII
1901
LYNND
1906
INQES
1911
GVAFH
1916
NDSFQ
1921
LGELR
1926
LHLMA
1931
SSGKM
1936
FKDGS
1941
MNVSV
1946
KLKTC
1951
TLDDL
1956
REGIE
1961
RATSR
1966
MIDRK
1971
NDQDN
1976
NSSMI
1981
DISYK
1986
QDKNG
1991
SQIDA
1996
VLDKL
2001
YVCAS
2006
VEFLM
2011
TVADF
2016
FIKAV
2021
PQSPE
2026
NVAKE
2031
TQILP
2036
RQTAT
2041
GKVKI
2046
EKDDS
2051
VRPNM
2056
TLKAM
2061
ITDPE
2066
VVFVA
2071
SLTKA
2076
DAPAL
2081
TASFQ
2086
CNLSL
2091
STSKL
2096
EQMME
2101
ASVRD
2106
LKVLA
2111
CPFLR
2116
EKRGK
2121
NITTV
2126
LQPCS
2131
LFMEK
2136
CTWAS
2141
GKQNI
2146
NIMVK
2151
EFIIK
2156
ISPII
2161
LNTVL
2166
TIMAA
2171
LSPKT
2176
KEDGS
2181
KDTSK
2186
EMENL
2191
WGIKS
2196
INDYN
2201
TWFLG
2206
VDTAT
2211
EITES
2216
FKGIE
2221
HSLIE
2226
ENCGV
2231
VVESI
2236
QVTLE
2241
CGLGH
2246
RTVPL
2251
LLAES
2256
KFSGN
2261
IKNWT
2266
SLMAA
2271
VADVT
2276
LQVHY
2281
YNEIH
2286
AVWEP
2291
LIERV
2296
EGKRQ
2301
WNLRL
2306
DVKKN
2311
PVQDK
2316
SLLPG
2321
DDFIP
2326
EPQMA
2331
IHISS
2336
GNTMN
2341
ITISK
2346
SCLNV
2351
FNNLA
2356
KGFSE
2361
GTAST
2366
FDYSL
2371
KDRAP
2376
FTVKN
2381
AVGVP
2386
IKVKP
2391
NCNLR
2396
VMGFP
2401
EKSDI
2406
FDVDA
2411
GQNLE
2416
LEYAS
2421
MVPSS
2426
QGNLS
2431
ILSRQ
2436
ESSFF
2441
TLTIV
2446
PHGYT
2451
EVANI
2456
PVARP
2461
GRRLY
2466
NVRNP
2471
NASHS
2476
DSVLV
2481
QIDAT
2486
EGNKV
2491
ITLRS
2496
PLQIK
2501
NHFSI
2506
AFIIY
2511
KFVKN
2516
VKLLE
2521
RIGIA
2526
RPEEE
2531
FHVPL
2536
DSYRC
2541
QLFIQ
2546
PAGIL
2551
EHQYK
2556
ESTTY
2561
ISWKE
2566
ELHRS
2571
REVRC
2576
MLQCP
2581
SVEVS
2586
FLPLI
2591
VNTVA
2596
LPDEL
2601
SYICT
2606
HGEDW
2611
DVAYI
2616
IHLYP
2621
SLTLR
2626
NLLPY
2631
SLRYL
2636
LEGTA
2641
ETHEL
2646
AEGST
2651
ADVLH
2656
SRISG
2661
EIMEL
2666
VLVKY
2671
QGKNW
2676
NGHFR
2681
IRDTL
2686
PEFFP
2691
VCFSS
2696
DSTEV
2701
TTVDL
2706
SVHVR
2711
RIGSR
2716
MVLSV
2721
FSPYW
2726
LINKT
2731
TRVLQ
2736
YRSED
2741
IHVKH
2746
PADFR
2751
DIILF
2756
SFKKK
2761
NIFTK
2766
NKVQL
2771
KISTS
2776
AWSSS
2781
FSLDT
2786
VGSYG
2791
CVKCP
2796
ANNME
2801
YLVGV
2806
SIKMS
2811
SFNLS
2816
RIVTL
2821
TPFCT
2826
IANKS
2831
SLELE
2836
VGEIA
2841
SDGSM
2846
PTNKW
2851
NYIAS
2856
SECLP
2861
FWPES
2866
LSGKL
2871
CVRVV
2876
GCEGS
2881
SKPFF
2886
YNRQD
2891
NGTLL
2896
SLEDL
2901
NGGIL
2906
VDVNT
2911
AEHST
2916
VITFS
2921
DYHEG
2926
SAPAL
2931
IMNHT
2936
PWDIL
2941
TYKQS
2946
GSPEE
2951
MVLLP
2956
RQARL
2961
FAWAD
2966
PTGTR
2971
KLTWT
2976
YAANV
2981
GEHDL
2986
LKDGC
2991
GQFPY
2996
DANIQ
3001
IHWVS
3006
FLDGR
3011
QRVLL
3016
FTDDV
3021
ALVSK
3026
ALQAE
3031
EMEQA
3036
DYEIT
3041
LSLHS
3046
LGLSL
3051
VNNES
3056
KQEVS
3061
YIGIT
3066
SSGVV
3071
WEVKP
3076
KQKWK
3081
PFSQK
3086
QIILL
3091
EQSYQ
3096
KHQIS
3101
RDHGW
3106
IKLDN
3111
NFEVN
3116
FDKDP
3121
MEMRL
3126
PIRSP
3131
IKRDF
3136
LSGIQ
3141
IEFKQ
3146
SSHQR
3151
SLRAR
3156
LYWLQ
3161
VDNQL
3166
PGAMF
3171
PVVFH
3176
PVAPP
3181
KSIAL
3186
DSEPK
3191
PFIDV
3196
SVITR
3201
FNEYS
3206
KVLQF
3211
KYFMV
3216
LIQEM
3221
ALKID
3226
QGFLG
3231
AIIAL
3236
FTPTT
3241
DPEAE
3246
RRRTK
3251
LIQQD
3256
IDALN
3261
AELME
3266
TSMTD
3271
MSILS
3276
FFEHF
3281
HISPV
3286
KLHLS
3291
LSLGS
3296
GGEES
3301
DKEKQ
3306
EMFAV
3311
HSVNL
3316
LLKSI
3321
GATLT
3326
DVDDL
3331
IFKLA
3336
YYEIR
3341
YQFYK
3346
RDQLI
3351
WSVVR
3356
HYSEQ
3361
FLKQM
3366
YVLVL
3371
GLDVL
3376
GNPFG
3381
LIRGL
3386
SEGVE
3391
ALFYE
3396
PFQGA
3401
VQGPE
3406
EFAEG
3411
LVIGV
3416
RSLFG
3421
HTVGG
3426
AAGVV
3431
SRITG
3436
SVGKG
3441
LAAIT
3446
MDKEY
3451
QQKRR
3456
EELSR
3461
QPRDF
3466
GDSLA
3471
RGGKG
3476
FLRGV
3481
VGGVT
3486
GIITK
3491
PVEGA
3496
KKEGA
3501
AGFFK
3506
GIGKG
3511
LVGAV
3516
ARPTG
3521
GIVDM
3526
ASSTF
3531
QGIQR
3536
AAEST
3541
EEVSS
3546
LRPPR
3551
LIHED
3556
GIIRP
3561
YDRQE
3566
SEGSD
3571
LLEQE
3576
LEIQE
3581
Mutation Information
DNA mutation:
None
Peptide Range:
62 ~ 86
Mut AA position:
74 (13 in Wild Type peptide)
Alignment
Wild Type:
"IDKLTLKIPWKNLYGEAVVATLEGL
||||||||||||.||||||||||||
Mutant:
IDKLTLKIPWKNFYGEAVVATLEGL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay