Immunogenicity 12474
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
FANCA
Transcript ID
uc002bfn.2
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (349 aa)
MGLGQ
1
AAWKE
6
ARVFL
11
QNLLS
16
VSQAR
21
LRDDT
26
ELRKC
31
AFISQ
36
ASATM
41
HLPAT
46
IGDYT
51
DFYSS
56
RQHAT
61
NVGIM
66
FRDKE
71
NALMP
76
NWLHL
81
PVGYH
86
GRASS
91
VVVSG
96
TPIRR
101
PMGQM
106
KPDDS
111
KPPVY
116
GACKL
121
LDMEL
126
EMAFF
131
VGPGN
136
RLGEP
141
IPISK
146
AHEHI
151
FGMVL
156
MNDWS
161
ARDIQ
166
KWEYV
171
PLGPF
176
LGKSF
181
GTTVS
186
PWVVP
191
MDALM
196
PFAVP
201
NPKQD
206
PRPLP
211
YLCHD
216
EPYTF
221
DINLS
226
VNLKG
231
EGMSQ
236
AATIC
241
KSNFK
246
YMYWT
251
MLQQL
256
THHSV
261
NGCNL
266
RPGDL
271
LASGT
276
ISGPE
281
PENFG
286
SMLEL
291
SWKGT
296
KPIDL
301
GNGQT
306
RKFLL
311
DGDEV
316
IITGY
321
CQGDG
326
YRIGF
331
GQCAG
336
KVLPA
341
LLPS
346
Mutation Information
DNA mutation:
None
Peptide Range:
56 ~ 80
Mut AA position:
68 (13 in Wild Type peptide)
Alignment
Wild Type:
"DFYSSRQHATNVGIMFRDKENALMP
||||||||||||.||||||||||||
Mutant:
DFYSSRQHATNVRIMFRDKENALMP"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) FAH
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
COS7
Assay
IFNg ELISPOT assay