Immunogenicity 12495
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ALPK3
Transcript ID
uc002ble.3
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (1907 aa)
MEVAW
1
LVYVL
6
GQQPL
11
ARQGE
16
GQSRL
21
VPGRG
26
LVLWL
31
PGLPR
36
SSPSW
41
PAVDL
46
APLAP
51
ARPRG
56
PLICH
61
TGHEQ
66
AGREP
71
GPGSS
76
TKGPV
81
LHDQD
86
TRCAF
91
LPRPP
96
GPLQT
101
RRYCR
106
HQGRQ
111
GSGLG
116
AGPGA
121
GTWAP
126
APPGV
131
SKPRC
136
PGRAR
141
PGEGQ
146
QQVTT
151
ARPPA
156
INRGA
161
RQPRA
166
GAAAA
171
GRGPG
176
AGAWR
181
TGEAA
186
ASAGP
191
AVGEG
196
GAMGS
201
RRAPS
206
RGWGA
211
GGRSG
216
AGGDG
221
EDDGP
226
VWIPS
231
PASRS
236
YLLSV
241
RPETS
246
LSSNR
251
LSHPS
256
SGRST
261
FCSII
266
AQLTE
271
ETQPL
276
FETTL
281
KSRSV
286
SEDSD
291
VRFTC
296
IVTGY
301
PEPEV
306
TWYKD
311
DTELD
316
RYCGL
321
PKYEI
326
THQGN
331
RHTLQ
336
LYRCR
341
EEDAA
346
IYQAS
351
AQNSK
356
GIVSC
361
SGVLE
366
VGTMT
371
EYKIH
376
QRWFA
381
KLKRK
386
AAAKL
391
REIEQ
396
SWKHE
401
KAVPG
406
EVDTL
411
RKLSP
416
DRFQR
421
KRRLS
426
GAQAP
431
GPSVP
436
TREPE
441
GGTLA
446
AWQEG
451
ETETA
456
QHSGL
461
GLINS
466
FASGE
471
VTTNG
476
EAAPE
481
NGEDG
486
EHGLL
491
TYICD
496
AMELG
501
PQRAL
506
KEESG
511
AKKKK
516
KDEES
521
KQGLR
526
KPELE
531
KAAQS
536
RRSSE
541
NCIPS
546
SDEPD
551
SCGTQ
556
GPVGV
561
EQVQT
566
QPRGR
571
AARGP
576
GSSGT
581
DSTRK
586
PASAV
591
GTPDK
596
AQKAP
601
GPGPG
606
QEVYF
611
SLKDM
616
YLENT
621
QAVRP
626
LGEEG
631
PQTLS
636
VRAPG
641
ESPKG
646
KAPLR
651
ARSEG
656
VPGAP
661
GQPTH
666
SLTPQ
671
PTRPF
676
NRKRF
681
APPKP
686
KGEAT
691
TDSKP
696
ISSLS
701
QAPEC
706
GAQSL
711
GKAPP
716
QASVQ
721
VPTPP
726
ARRRH
731
GTRDS
736
TLQGQ
741
AGHRT
746
PGEVL
751
ECQTT
756
TAPTM
761
SASSS
766
SDVAS
771
IGVST
776
SGSQG
781
IIEPM
786
DMETQ
791
EDGRT
796
SANQR
801
TGSKK
806
NVQAD
811
GKIQV
816
DGRTR
821
GDGTQ
826
TAQRT
831
RADRK
836
TQVDA
841
GTQES
846
KRPQS
851
DRSAQ
856
KGMMT
861
QGRAE
866
TQLET
871
TQAGE
876
KIQED
881
RKAQA
886
DKGTQ
891
EDRRM
896
QGEKG
901
MQGEK
906
GTQSE
911
GSAPT
916
AMEGQ
921
SEQEV
926
ATSLG
931
PPSRT
936
PKLPP
941
TAGPR
946
APLNI
951
ECFVQ
956
TPEGS
961
CFPKK
966
PGCLP
971
RSEEA
976
VVTAS
981
RNHEQ
986
TVLGP
991
LSGNL
996
MLPAQ
1001
PPHEG
1006
SVEQV
1011
GGERC
1016
RGPQS
1021
SGPVE
1026
AKQED
1031
SPFQC
1036
PKEER
1041
PGGVP
1046
CMDQG
1051
GCPLA
1056
GLSQE
1061
VPTMP
1066
SLPGT
1071
GLTAS
1076
PKAGP
1081
CSTPT
1086
SQHGS
1091
TATFL
1096
PSEDQ
1101
VLMSS
1106
APTLH
1111
LGLGT
1116
PTQSH
1121
PPETM
1126
ATSSE
1131
GACAQ
1136
VPDVE
1141
GRTPG
1146
PRSCD
1151
PGLID
1156
SLKNY
1161
LLLLL
1166
KLSST
1171
ETSGA
1176
GGESQ
1181
VGAAT
1186
GGLVP
1191
SATLT
1196
PTVEV
1201
AGLSP
1206
RTSRR
1211
ILERV
1216
ENNHL
1221
VQSAQ
1226
TLLLS
1231
PCTSR
1236
RLTGL
1241
LDREV
1246
QAGRQ
1251
ALAAA
1256
RGSWG
1261
PGPSS
1266
LTVPA
1271
IVVDE
1276
EDPGL
1281
ASEGA
1286
SEGEG
1291
EVSPE
1296
GPGLL
1301
GASQE
1306
SSMAG
1311
RLGEA
1316
GGQAA
1321
PGQGP
1326
SAESI
1331
AQEPS
1336
QEEKF
1341
PGEAL
1346
TGLPA
1351
ATPEE
1356
LALGA
1361
RRKRF
1366
LPKVR
1371
AAGDG
1376
EATTP
1381
EERES
1386
PTVSP
1391
RGPRK
1396
SLVPG
1401
SPGTP
1406
GRERR
1411
SPTQG
1416
RKASM
1421
LEVPR
1426
AEEEL
1431
AAGDL
1436
GPSPK
1441
AGGLD
1446
TEVAL
1451
DEGKQ
1456
ETLAK
1461
PRKAK
1466
DLLKA
1471
PQVIR
1476
KIRVE
1481
QFPDA
1486
SGSLK
1491
LWCQF
1496
FNILS
1501
DSVLT
1506
WAKDQ
1511
RPVGE
1516
VGRSA
1521
GDEGP
1526
AALAI
1531
VQASP
1536
VDCGV
1541
YRCTI
1546
HNEHG
1551
SASTD
1556
FCLSP
1561
EVLSG
1566
FISRE
1571
EGEVG
1576
EEIEM
1581
TPMVF
1586
AKGLA
1591
DSGCW
1596
GDKLF
1601
GRLVS
1606
EELRG
1611
GGYGC
1616
GLRKA
1621
SQAKV
1626
IYGLE
1631
PIFES
1636
GRTCI
1641
IKVSS
1646
LLVFG
1651
PSSET
1656
SLVGR
1661
NYDVT
1666
IQGCK
1671
IQNMS
1676
REYCK
1681
IFAAE
1686
ARAAP
1691
GFGEV
1696
PEIIP
1701
LYLIY
1706
RPANN
1711
IPYAT
1716
LEEDL
1721
GKPLE
1726
SYCSR
1731
EWGCA
1736
EAPTA
1741
SGSSE
1746
AMQKC
1751
QTFQH
1756
WLYQW
1761
TNGSF
1766
LVTDL
1771
AGVDW
1776
KMTDV
1781
QIATK
1786
LRGYQ
1791
GLKES
1796
CFPAL
1801
LDRFA
1806
SSHQC
1811
NAYCE
1816
LLGLT
1821
PLKGP
1826
EAAHP
1831
QAKAK
1836
GSKSP
1841
SAGRK
1846
GSQLS
1851
PQPQK
1856
KGLPS
1861
PQGTR
1866
KSAPS
1871
SKATP
1876
QASEP
1881
VTTQL
1886
LGQPP
1891
TQEEG
1896
SKAQG
1901
MR
1906
Mutation Information
DNA mutation:
None
Peptide Range:
1061 ~ 1085
Mut AA position:
1073 (13 in Wild Type peptide)
Alignment
Wild Type:
"GLSQEVPTMPSLPGTGLTASPKAGP
||||||||||||.||||||||||||
Mutant:
GLSQEVPTMPSLSGTGLTASPKAGP"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) ALPK3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay