Immunogenicity 12576

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PRSS54
Transcript ID
uc002eng.3
HLA INFO
B*27:02
TCR INFO

No TCR info found!

T cell Tumor cell B*27:02
sequence
Full length protein sequence (395 aa)
MVSAA
1
GLSGD
6
GKMRG
11
VLLVL
16
LGLLY
21
SSTSC
26
GVQKA
31
SVFYG
36
PDPKE
41
GLVSS
46
MEFPW
51
VVSLQ
56
DSQYT
61
HLAFG
66
CILSE
71
FWVLS
76
IASAI
81
QNRKD
86
IVVIV
91
GISNM
96
DPSKI
101
AHTEY
106
PVNTI
111
IIHED
116
FDNNS
121
MSNNI
126
ALLKT
131
DTAMH
136
FGNLV
141
QSICF
146
LGRML
151
HTPPV
156
LQNCW
161
VSGWN
166
PTSAT
171
GNHMT
176
MSVLR
181
KIFVK
186
DLDMC
191
PLYKL
196
QKTEC
201
GSHTK
206
EETKT
211
ACLGD
216
PGSPM
221
MCQLQ
226
QFDLW
231
VLRGV
236
LNFGG
241
ETCPG
246
LFLYT
251
KVEDY
256
SKWIT
261
SKAER
266
AGPPL
271
SSLHH
276
WEKLI
281
SFSHH
286
GPNAT
291
MTQKT
296
YSDSE
301
LGHVG
306
SYLQG
311
QRRTI
316
THSRL
321
GNSSR
326
DSLDV
331
REKDV
336
KESGR
341
SPEAS
346
VQPLY
351
YDYYG
356
GEVGE
361
GRIFA
366
GQNRL
371
YQPEE
376
IILVS
381
FVLVF
386
FCSSI
391
Mutation Information
DNA mutation:
None
Peptide Range:
24 ~ 48
Mut AA position:
36 (13 in Wild Type peptide)
Alignment
Wild Type:
"LYSSTSCGVQKASVFYGPDPKEGLV
||||||||||||.||||||||||||
Mutant:
LYSSTSCGVQKAFVFYGPDPKEGLV"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay