Immunogenicity 12601
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ADAMTS18
Transcript ID
uc002ffc.4
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1221 aa)
MECAL
1
LLACA
6
FPAAG
11
SGPPR
16
GLAGL
21
GRVAK
26
ALQLC
31
CLCCA
36
SVAAA
41
LASDS
46
SSGAS
51
GLNDD
56
YVFVT
61
PVEVD
66
SAGSY
71
ISHDI
76
LHNGR
81
KKRSA
86
QNARS
91
SLHYR
96
FSAFG
101
QELHL
106
ELKPS
111
AILSS
116
HFIVQ
121
VLGKD
126
GASET
131
QKPEV
136
QQCFY
141
QGFIR
146
NDSSS
151
SVAVS
156
TCAGL
161
SGLIR
166
TRKNE
171
FLISP
176
LPQLL
181
AQEHN
186
YSSPA
191
GHHPH
196
VLYKR
201
TAEEK
206
IQRYR
211
GYPGS
216
GRNYP
221
GYSPS
226
HIPHA
231
SQSRE
236
TEYHH
241
RRLQK
246
QHFCG
251
RRKKY
256
APKPP
261
TEDTY
266
LRFDE
271
YGSSG
276
RPRRS
281
AGKSQ
286
KGLNV
291
ETLVV
296
ADKKM
301
VEKHG
306
KGNVT
311
TYILT
316
VMNMV
321
SGLFK
326
DGTIG
331
SDINV
336
VVVSL
341
ILLEQ
346
EPGGL
351
LINHH
356
ADQSL
361
NSFCQ
366
WQSAL
371
IGKNG
376
KRHDH
381
AILLT
386
GFDIC
391
SWKNE
396
PCDTL
401
GFAPI
406
SGMCS
411
KYRSC
416
TINED
421
TGLGL
426
AFTIA
431
HESGH
436
NFGMI
441
HDGEG
446
NPCRK
451
AEGNI
456
MSPTL
461
TGNNG
466
VFSWS
471
SCSRQ
476
YLKKF
481
LSTPQ
486
AGCLV
491
DEPKQ
496
AGQYK
501
YPDKL
506
PGQIY
511
DADTQ
516
CKWQF
521
GAKAK
526
LCSLG
531
FVKDI
536
CKSLW
541
CHRVG
546
HRCET
551
KFMPA
556
AEGTV
561
CGLSM
566
WCRQG
571
QCVKF
576
GELGP
581
RPIHG
586
QWSAW
591
SKWSE
596
CSRTC
601
GGGVK
606
FQERH
611
CNNPK
616
PQYGG
621
LFCPG
626
SSRIY
631
QLCNI
636
NPCNE
641
NSLDF
646
RAQQC
651
AEYNS
656
KPFRG
661
WFYQW
666
KPYTK
671
VEEED
676
RCKLY
681
CKAEN
686
FEFFF
691
AMSGK
696
VKDGT
701
PCSPN
706
KNDVC
711
IDGVC
716
ELVGC
721
DHELG
726
SKAVS
731
DACGV
736
CKGDN
741
STCKF
746
YKGLY
751
LNQHK
756
ANEYY
761
PVVLI
766
PAGAR
771
SIEIQ
776
ELQVS
781
SSYLA
786
VRSLS
791
QKYYL
796
TGGWS
801
IDWPG
806
EFPFA
811
GTTFE
816
YQRSF
821
NRPER
826
LYAPG
831
PTNET
836
LVFEI
841
LMQGK
846
NPGIA
851
WKYAL
856
PKVMN
861
GTPPA
866
TKRPA
871
YTWSI
876
VQSEC
881
SVSCG
886
GGYIN
891
VKAIC
896
LRDQN
901
TQVNS
906
SFCSA
911
KTKPV
916
TEPKI
921
CNAFS
926
CPAYW
931
MPGEW
936
STCSK
941
ACAGG
946
QQSRK
951
IQCVQ
956
KKPFQ
961
KEEAV
966
LHSLC
971
PVSTP
976
TQVQA
981
CNSHA
986
CPPQW
991
SLGPW
996
SQCSK
1001
TCGRG
1006
VRKRE
1011
LLCKG
1016
SAAET
1021
LPESQ
1026
CTSLP
1031
RPELQ
1036
EGCVL
1041
GRCPK
1046
NSRLQ
1051
WVASS
1056
WSECS
1061
ATCGL
1066
GVRKR
1071
EMKCS
1076
EKGFQ
1081
GKLIT
1086
FPERR
1091
CRNIK
1096
KPNLD
1101
LEETC
1106
NRRAC
1111
PAHPV
1116
YNMVA
1121
GWYSL
1126
PWQQC
1131
TVTCG
1136
GGVQT
1141
RSVHC
1146
VQQGR
1151
PSSSC
1156
LLHQK
1161
PPVLR
1166
ACNTN
1171
FCPAP
1176
EKRED
1181
PSCVD
1186
FFNWC
1191
HLVPQ
1196
HGVCN
1201
HKFYG
1206
KQCCK
1211
SCTRK
1216
I
1221
Mutation Information
DNA mutation:
None
Peptide Range:
253 ~ 277
Mut AA position:
265 (13 in Wild Type peptide)
Alignment
Wild Type:
"FCGRRKKYAPKPPTEDTYLRFDEYG
||||||||||||.||||||||||||
Mutant:
FCGRRKKYAPKPSTEDTYLRFDEYG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) ADAMTS18
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
COS7
Assay
IFNg ELISPOT assay