Immunogenicity 12605

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
KCNG4
Transcript ID
uc010voc.2
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (519 aa)
MPMPS
1
RDGGL
6
HPRHH
11
HYGSH
16
SPWSQ
21
LLSSP
26
METPS
31
IKGLY
36
YRRVR
41
KVGAL
46
DASPV
51
DLKKE
56
ILINV
61
GGRRY
66
LLPWS
71
TLDRF
76
PLSRL
81
SKLRL
86
CRSYE
91
EIVQL
96
CDDYD
101
EDSQE
106
FFFDR
111
SPSAF
116
GVIVS
121
FLAAG
126
KLVLL
131
QEMCA
136
LSFQE
141
ELAYW
146
GIEEA
151
HLERC
156
CLRKL
161
LRKLE
166
ELEEL
171
AKLHR
176
EDVLR
181
QQRET
186
RRPAS
191
HSSRW
196
GLCMN
201
RLREM
206
VENPQ
211
SGLPG
216
KVFAC
221
LSILF
226
VATTA
231
VSLCV
236
STMPD
241
LRAEE
246
DQGEC
251
SRKCY
256
YIFIV
261
ETICV
266
AWFSL
271
EFCLR
276
FVQAQ
281
DKCQF
286
FQGPL
291
NIIDI
296
LAISP
301
YYVSL
306
AVSEE
311
PPEDG
316
ERPSG
321
SSYLE
326
KVGLV
331
LRVLR
336
ALRIL
341
YVMRL
346
ARHSL
351
GLQTL
356
GLTVR
361
RCTRE
366
FGLLL
371
LFLAV
376
AITLF
381
SPLVY
386
VAEKE
391
SGRVL
396
EFTSI
401
PASYW
406
WAIIS
411
MTTVG
416
YGDMV
421
PRSVP
426
GQMVA
431
LSSIL
436
SGILI
441
MAFPA
446
TSIFH
451
TFSHS
456
YLELK
461
KEQEQ
466
LQARL
471
RHLQN
476
TGPAS
481
ECELL
486
DPHVA
491
SEHEL
496
MNDVN
501
DLILE
506
GPALP
511
IMHM
516
Mutation Information
DNA mutation:
None
Peptide Range:
245 ~ 269
Mut AA position:
257 (13 in Wild Type peptide)
Alignment
Wild Type:
"DLRAEEDQGECSRKCYYIFIVETIC
||||||||||||.||||||||||||
Mutant:
DLRAEEDQGECSWKCYYIFIVETIC"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay