Immunogenicity 12621
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DNAH2
Transcript ID
uc002giu.1
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (4427 aa)
MSSKA
1
EKKQR
6
LSGRG
11
SSQAS
16
WSGRA
21
TRAAV
26
ATQEQ
31
GNAPA
36
VSEPE
41
LQAEL
46
PKEEP
51
EPRLE
56
GPQAQ
61
SEESV
66
EPEAD
71
VKPLF
76
LSRAA
81
LTGLA
86
DAVWT
91
QEHDA
96
ILEHF
101
AQDPT
106
ESILT
111
IFIDP
116
CFGLK
121
LELGM
126
PVQTQ
131
NQLVY
136
FIRQA
141
PVPIT
146
WENFE
151
ATVQF
156
GTVRG
161
PYIPA
166
LLRLL
171
GGVFA
176
PQIFA
181
NTGWP
186
ESIRN
191
HFASH
196
LHKFL
201
ACLTD
206
TRYKL
211
EGHTV
216
LYIPA
221
EAMNM
226
KPEMV
231
IKDKE
236
LVQRL
241
ETSMI
246
HWTRQ
251
IKEML
256
SAQET
261
VETGE
266
NLGPL
271
EEIEF
276
WRNRC
281
MDLSG
286
ISKQL
291
VKKGV
296
KHVES
301
ILHLA
306
KSSYL
311
APFMK
316
LAQQI
321
QDGSR
326
QAQSN
331
LTFLS
336
ILKEP
341
YQELA
346
FMKPK
351
DISSK
356
LPKLI
361
SLIRI
366
IWVNS
371
PHYNT
376
RERLT
381
SLFRK
386
VCDCQ
391
YHFAR
396
WEDGK
401
QGPLP
406
CFFGA
411
QGPQI
416
TRNLL
421
EIEDI
426
FHKNL
431
HTLRA
436
VRGGI
441
LDVKN
446
TCWHE
451
DYNKF
456
RAGIK
461
DLEVM
466
TQNLI
471
TSAFE
476
LVRDV
481
PHGVL
486
LLDTF
491
HRLAS
496
REAIK
501
RTYDK
506
KAVDL
511
YMLFN
516
SELAL
521
VNRER
526
NKKWP
531
DLEPY
536
VAQYS
541
GKARW
546
VHILR
551
RRIDR
556
VMTCL
561
AGAHF
566
LPRIG
571
TGKES
576
VHTYQ
581
QMVQA
586
IDELV
591
RKTFQ
596
EWTSS
601
LDKDC
606
IRRLD
611
TPLLR
616
ISQEK
621
AGMLD
626
VNFDK
631
SLLIL
636
FAEID
641
YWERL
646
LFETP
651
HYVVN
656
VAERA
661
EDLRI
666
LRENL
671
LLVAR
676
DYNRI
681
IAMLS
686
PDEQA
691
LFKER
696
IRLLD
701
KKIHP
706
GLKKL
711
HWALK
716
GASAF
721
FITEC
726
RIHAS
731
KVQMI
736
VNEFK
741
ASTLT
746
IGWRA
751
QEMSE
756
KLLVR
761
ISGKR
766
VYRDL
771
EFEED
776
QREHR
781
AAVQQ
786
KLMNL
791
HQDVV
796
TIMTN
801
SYEVF
806
KNDGP
811
EIQQQ
816
WMLYM
821
IRLDR
826
MMEDA
831
LRLNV
836
KWSLL
841
ELSKA
846
INGDG
851
KTSPN
856
PLFQV
861
LVILK
866
NDLQG
871
SVAQV
876
EFSPT
881
LQTLA
886
GVVND
891
IGNHL
896
FSTIS
901
VFCHL
906
PDILT
911
KRKLH
916
REPIQ
921
TVVEQ
926
DEDIK
931
KIQTQ
936
ISSGM
941
TNNAS
946
LLQNY
951
LKTWD
956
MYREI
961
WEINK
966
DSFIH
971
RYQRL
976
NPPVS
981
SFVAD
986
IARYT
991
EVANN
996
VQKEE
1001
TVTNI
1006
QFVLL
1011
DCSHL
1016
KFSLV
1021
QHCNE
1026
WQNKF
1031
ATLLR
1036
EMAAG
1041
RLLEL
1046
HTYLK
1051
ENAEK
1056
ISRPP
1061
QTLEE
1066
LGVSL
1071
QLVDA
1076
LKHDL
1081
ANVET
1086
QIPPI
1091
HEQFA
1096
ILEKY
1101
EVPVE
1106
DSVLE
1111
MLDSL
1116
NGEWV
1121
VFQQT
1126
LLDSK
1131
QMLKK
1136
HKEKF
1141
KTGLI
1146
HSADD
1151
FKKKA
1156
HTLLE
1161
DFEFK
1166
GHFTS
1171
NVGYM
1176
SALDQ
1181
ITQVR
1186
AMLMA
1191
MREEE
1196
NSLRA
1201
NLGIF
1206
KIEQP
1211
PSKDL
1216
QNLEK
1221
ELDAL
1226
QQIWE
1231
IARDW
1236
EENWN
1241
EWKTG
1246
RFLIL
1251
QTETM
1256
ETTAH
1261
GLFRR
1266
LTKLA
1271
KEYKD
1276
RNWEI
1281
IETTR
1286
SKIEQ
1291
FKRTM
1296
PLISD
1301
LRNPA
1306
LRERH
1311
WDQVR
1316
DEIQR
1321
EFDQE
1326
SESFT
1331
LEQIV
1336
ELGMD
1341
QHVEK
1346
IGEIS
1351
ASATK
1356
ELAIE
1361
VALQN
1366
IAKTW
1371
DVTQL
1376
DIVPY
1381
KDKGH
1386
HRLRG
1391
TEEVF
1396
QALED
1401
NQVAL
1406
STMKA
1411
SRFVK
1416
AFEKD
1421
VDHWE
1426
RCLSL
1431
ILEVI
1436
EMILT
1441
VQRQW
1446
MYLEN
1451
IFLGE
1456
DIRKQ
1461
LPNES
1466
TLFDQ
1471
VNSNW
1476
KAIMD
1481
RMNKD
1486
NNALR
1491
STHHP
1496
GLLDT
1501
LIEMN
1506
TILED
1511
IQKSL
1516
DMYLE
1521
TKRHI
1526
FPRFY
1531
FLSND
1536
DLLEI
1541
LGQSR
1546
NPEAV
1551
QPHLK
1556
KCFDN
1561
IKLLR
1566
IQKVG
1571
GPSSK
1576
WEAVG
1581
MFSGD
1586
GEYID
1591
FLHSV
1596
FLEGP
1601
VESWL
1606
GDVEQ
1611
TMRVT
1616
LRDLL
1621
RNCHL
1626
ALRKF
1631
LNKRD
1636
KWVKE
1641
WAGQV
1646
VITAS
1651
QIQWT
1656
ADVTK
1661
CLLTA
1666
KERAD
1671
KKILK
1676
VMKKN
1681
QVSIL
1686
NKYSE
1691
AIRGN
1696
LTKIM
1701
RLKIV
1706
ALVTI
1711
EIHAR
1716
DVLEK
1721
LYKSG
1726
LMDVN
1731
SFDWL
1736
SQLRF
1741
YWEKD
1746
LDDCV
1751
IRQTN
1756
TQFQY
1761
NYEYL
1766
GNSGR
1771
LVITP
1776
LTDRC
1781
YMTLT
1786
TALHL
1791
HRGGS
1796
PKGPA
1801
GTGKT
1806
ETVKD
1811
LGKAL
1816
GIYVI
1821
VVNCS
1826
EGLDY
1831
KSMGR
1836
MYSGL
1841
AQTGA
1846
WGCFD
1851
EFNRI
1856
NIEVL
1861
SVVAH
1866
QILCI
1871
LSALA
1876
AGLTH
1881
FHFDG
1886
FEINL
1891
VWSCG
1896
IFITM
1901
NPGYA
1906
GRTEL
1911
PENLK
1916
SMFRP
1921
IAMVV
1926
PDSTL
1931
IAEII
1936
LFGEG
1941
FGNCK
1946
ILAKK
1951
VYTLY
1956
SLAVQ
1961
QLSRQ
1966
DHYDF
1971
GLRAL
1976
TSLLR
1981
YAGKK
1986
RRLQP
1991
DLTDE
1996
EVLLL
2001
SMRDM
2006
NIAKL
2011
TSVDA
2016
PLFNA
2021
IVQDL
2026
FPNIE
2031
LPVID
2036
YGKLR
2041
ETVEQ
2046
EIRDM
2051
GLQST
2056
PFTLT
2061
KVFQL
2066
YETKN
2071
SRHST
2076
MIVGC
2081
TGSGK
2086
TASWR
2091
ILQAS
2096
LSSLC
2101
RAGDP
2106
NFNIV
2111
REFPL
2116
NPKAL
2121
SLGEL
2126
YGEYD
2131
LSTNE
2136
WTDGI
2141
LSSVM
2146
RTACA
2151
DEKPD
2156
EKWIL
2161
FDGPV
2166
DTLWI
2171
ENMNS
2176
VMDDN
2181
KVLTL
2186
INGER
2191
IAMPE
2196
QVSLL
2201
FEVED
2206
LAMAS
2211
PATVS
2216
RCGMV
2221
YTDYA
2226
DLGWK
2231
PYVQS
2236
WLEKR
2241
PKAEV
2246
EPLQR
2251
MFEKL
2256
INKML
2261
AFKKD
2266
NCKEL
2271
VPLPE
2276
YSGIT
2281
SLCKL
2286
YSALA
2291
TPENG
2296
VNPAD
2301
GENYV
2306
TMVEM
2311
TFVFS
2316
MIWSV
2321
CASVD
2326
EEGRK
2331
RIDSY
2336
LREIE
2341
GSFPN
2346
KDTVY
2351
EYFVD
2356
PKIRS
2361
WTSFE
2366
DKLPK
2371
SWRYP
2376
PNAPF
2381
YKIMV
2386
PTVDT
2391
VRYNY
2396
LVSSL
2401
VANQN
2406
PILLV
2411
GPVGT
2416
GKTSI
2421
AQSVL
2426
QSLPS
2431
SQWSV
2436
LVVNM
2441
SAQTT
2446
SNNVQ
2451
SIIES
2456
RVEKR
2461
TKGVY
2466
VPFGG
2471
KSMIT
2476
FMDDL
2481
NMPAK
2486
DMFGS
2491
QPPLE
2496
LIRLW
2501
IDYGF
2506
WYDRT
2511
KQTIK
2516
YIREM
2521
FLMAA
2526
MGPPG
2531
GGRTV
2536
ISPRL
2541
RSRFN
2546
IINMT
2551
FPTKS
2556
QIIRI
2561
FGTMI
2566
NQKLQ
2571
DFEEE
2576
VKPIG
2581
NVVTE
2586
ATLDM
2591
YNTVV
2596
QRFLP
2601
TPTKM
2606
HYLFN
2611
LRDIS
2616
KVFQG
2621
MLRAN
2626
KDFHD
2631
TKSSI
2636
TRLWI
2641
HECFR
2646
VFSDR
2651
LVDAA
2656
DTEAF
2661
MGIIS
2666
DKLGS
2671
FFDLT
2676
FHHLC
2681
PSKRP
2686
PIFGD
2691
FLKEP
2696
KVYED
2701
LTDLT
2706
VLKTV
2711
METAL
2716
NEYNL
2721
SPSVV
2726
PMQLV
2731
LFREA
2736
IEHIT
2741
RIVRV
2746
IGQPR
2751
GNMLL
2756
VGIGG
2761
SGRQS
2766
LARLA
2771
SSICD
2776
YTTFQ
2781
IEVTK
2786
HYRKQ
2791
EFRDD
2796
IKRLY
2801
RQAGV
2806
ELKTT
2811
SFIFV
2816
DTQIA
2821
DESFL
2826
EDINN
2831
ILSSG
2836
EVPNL
2841
YKPDE
2846
FEEIQ
2851
SHIID
2856
QARVE
2861
QVPES
2866
SDSLF
2871
AYLIE
2876
RVQNN
2881
LHIVL
2886
CLSPM
2891
GDPFR
2896
NWIRQ
2901
YPALV
2906
NCTTI
2911
NWFSE
2916
WPQEA
2921
LLEVA
2926
EKCLI
2931
GVDLG
2936
TQENI
2941
HRKVA
2946
QIFVT
2951
MHWSV
2956
AQYSQ
2961
KMLLE
2966
LRRHN
2971
YVTPT
2976
KYLEL
2981
LSGYK
2986
KLLGE
2991
KRQEL
2996
LAQAN
3001
KLRTG
3006
LFKID
3011
ETREK
3016
VQVMS
3021
LELED
3026
AKKKV
3031
AEFQK
3036
QCEEY
3041
LVIIV
3046
QQKRE
3051
ADEQQ
3056
KAVTA
3061
NSEKI
3066
AVEEI
3071
KCQAL
3076
ADNAQ
3081
KDLEE
3086
ALPAL
3091
EEAMR
3096
ALESL
3101
NKKDI
3106
GEIKS
3111
YGRPP
3116
AQVEI
3121
VMQAV
3126
MILRG
3131
NEPTW
3136
AEAKR
3141
QLGEQ
3146
NFIKS
3151
LINFD
3156
KDNIS
3161
DKVLK
3166
KIGAY
3171
CAQPD
3176
FQPDI
3181
IGRVS
3186
LAAKS
3191
LCMWV
3196
RAMEL
3201
YGRLY
3206
RVVEP
3211
KRIRM
3216
NAALA
3221
QLREK
3226
QAALA
3231
EAQEK
3236
LREVA
3241
EKLEM
3246
LKKQY
3251
DEKLA
3256
QKEEL
3261
RKKSE
3266
EMELK
3271
LERAG
3276
MLVSG
3281
LAGEK
3286
ARWEE
3291
TVQGL
3296
EEDLG
3301
YLVGD
3306
CLLAA
3311
AFLSY
3316
MGPFL
3321
TNYRD
3326
EIVNQ
3331
IWIGK
3336
IWELQ
3341
VPCSP
3346
SFAID
3351
NFLCN
3356
PTKVR
3361
DWNIQ
3366
GLPSD
3371
AFSTE
3376
NGIIV
3381
TRGNR
3386
WALMI
3391
DPQAQ
3396
ALKWI
3401
KNMEG
3406
GQGLK
3411
IIDLQ
3416
MSDYL
3421
RILEH
3426
AIHFG
3431
YPVLL
3436
QNVQE
3441
YLDPT
3446
LNPML
3451
NKSVA
3456
RIGGR
3461
LLMRI
3466
GDKEV
3471
EYNTN
3476
FRFYI
3481
TTKLS
3486
NPHYS
3491
PETSA
3496
KTTIV
3501
NFAVK
3506
EQGLE
3511
AQLLG
3516
IVVRK
3521
ERPEL
3526
EEQKD
3531
SLVIN
3536
IAAGK
3541
RKLKE
3546
LEDEI
3551
LRLLN
3556
EATGS
3561
LLDDV
3566
QLVNT
3571
LHTSK
3576
ITATE
3581
VTEQL
3586
ETSET
3591
TEINT
3596
DLARE
3601
AYRPC
3606
AQRAS
3611
ILFFV
3616
LNDMG
3621
CIDPM
3626
YQFSL
3631
DAYIS
3636
LFILS
3641
IDKSH
3646
RSNKL
3651
EDRID
3656
YLNDY
3661
HTYAV
3666
YRYTC
3671
RTLFE
3676
RHKLL
3681
FSFHM
3686
CAKIL
3691
ETSGK
3696
LNMDE
3701
YNFFL
3706
RGGVV
3711
LDREG
3716
QMDNP
3721
CSSWL
3726
ADAYW
3731
DNITE
3736
LDKLT
3741
NFHGL
3746
MNSFE
3751
QYPRD
3756
WHLWY
3761
TNAAP
3766
EKAML
3771
PGEWE
3776
NACNE
3781
MQRML
3786
IVRSL
3791
RQDRV
3796
AFCVT
3801
SFIIT
3806
NLGSR
3811
FIEPP
3816
VLNMK
3821
SVLED
3826
STPRS
3831
PLVFI
3836
LSPGV
3841
DPTSA
3846
LLQLA
3851
EHMGM
3856
AQRFH
3861
ALSLG
3866
QGQAP
3871
IAARL
3876
LREGV
3881
TQGHW
3886
VFLAN
3891
CHLSL
3896
SWMPN
3901
LDKLV
3906
EQLQV
3911
EDPHP
3916
SFRLW
3921
LSSIP
3926
HPDFP
3931
ISILQ
3936
VSIKM
3941
TTEPP
3946
KGLKA
3951
NMTRL
3956
YQLMS
3961
EPQFS
3966
RCSKP
3971
AKYKK
3976
LLFSL
3981
CFFHS
3986
VLLER
3991
KKFLQ
3996
LGWNI
4001
IYGFN
4006
DSDFE
4011
VSENL
4016
LSLYL
4021
DEYEE
4026
TPWDA
4031
LKYLI
4036
AGINY
4041
GGHVT
4046
DDWDR
4051
RLLTT
4056
YINDY
4061
FCDQS
4066
LSTPF
4071
HRLSA
4076
LETYF
4081
IPKDG
4086
SLASY
4091
KEYIS
4096
LLPGM
4101
DPPEA
4106
FGQHP
4111
NADVA
4116
SQITE
4121
AQTLF
4126
DTLLS
4131
LQPQI
4136
TPTRA
4141
GGQTR
4146
EEKVL
4151
ELAAD
4156
VKQKI
4161
PEMID
4166
YEGTQ
4171
KLLAL
4176
DPSPL
4181
NVVLL
4186
QEIQR
4191
YNTLM
4196
QTILF
4201
SLTDL
4206
EKGIQ
4211
GLIVM
4216
STSLE
4221
EIFNC
4226
IFDAH
4231
VPPLW
4236
GKAYP
4241
SQKPL
4246
AAWTR
4251
DLAMR
4256
VEQFE
4261
LWASR
4266
ARPPV
4271
IFWLS
4276
GFTFP
4281
TGFLT
4286
AVLQS
4291
SARQN
4296
NVSVD
4301
SLSWE
4306
FIVST
4311
VDDSN
4316
LVYPP
4321
KDGVW
4326
VRGLY
4331
LEGAG
4336
WDRKN
4341
SCLVE
4346
AEPMQ
4351
LVCLM
4356
PTIHF
4361
RPAES
4366
RKKSA
4371
KGMYS
4376
CPCYY
4381
YPNRA
4386
GSSDR
4391
ASFVI
4396
GIDLR
4401
SGAMT
4406
PDHWI
4411
KRGTA
4416
LLMSL
4421
DS
4426
Mutation Information
DNA mutation:
None
Peptide Range:
2620 ~ 2644
Mut AA position:
2632 (13 in Wild Type peptide)
Alignment
Wild Type:
"SKVFQGMLRANKDFHDTKSSITRLW
||||||||||||.||||||||||||
Mutant:
SKVFQGMLRANKNFHDTKSSITRLW"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DNAH2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay