Immunogenicity 12661
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MLLT6
Transcript ID
uc002hqi.4
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (1093 aa)
MKEMV
1
GGCCV
6
CSDER
11
GWAEN
16
PLVYC
21
DGHAC
26
SVAVH
31
QACYG
36
IVQVP
41
TGPWF
46
CRKCE
51
SQERA
56
ARVRC
61
ELCPH
66
KDGAL
71
KRTDN
76
GGWAH
81
VVCAL
86
YIPEV
91
QFANV
96
LTMEP
101
IVLQY
106
VPHDR
111
FNKTC
116
YICEE
121
QGRES
126
KAASG
131
ACMTC
136
NRHGC
141
RQAFH
146
VTCAQ
151
MAGLL
156
CEEEV
161
LEVDN
166
VKYCG
171
YCKYH
176
FSKMK
181
TSRHS
186
SGGGG
191
GGAGG
196
GGGSM
201
GGGGS
206
GFISG
211
RRSRS
216
ASPST
221
QQEKH
226
PTHHE
231
RGQKK
236
SRKDK
241
ERLKQ
246
KHKKR
251
PESPP
256
SILTP
261
PVVPT
266
ADKVS
271
SSASS
276
SSHHE
281
ASTQE
286
TSESS
291
RESKG
296
KKSSS
301
HSLSH
306
KGKKL
311
SSGKG
316
VSSFT
321
SASSS
326
SSSSS
331
SSSGG
336
PFQPA
341
VSSLQ
346
SSPDF
351
SAFPK
356
LEQPE
361
EDKYS
366
KPTAP
371
APSAP
376
PSPSA
381
PEPPK
386
ADLFE
391
QKVVF
396
SGFGP
401
IMRFS
406
TTTSS
411
SGRAR
416
APSPG
421
DYKSP
426
HVTGS
431
GASAG
436
THKRM
441
PALSA
446
TPVPA
451
DETPE
456
TGLKE
461
KKHKA
466
SKRSR
471
HGPGR
476
PKGSR
481
NKEGT
486
GGPAA
491
PSLPS
496
AQLAG
501
FTATA
506
ASPFS
511
GGSLV
516
SSGLG
521
GLSSR
526
TFGPS
531
GSLPS
536
LSLES
541
PLLGA
546
GIYTS
551
NKDPI
556
SHSGG
561
MLRAV
566
CSTPL
571
SSSLL
576
GPPGT
581
SALPR
586
LSRSP
591
FTSTL
596
PSSSA
601
SISTT
606
QVFSL
611
AGSTF
616
SLPST
621
HIFGT
626
PMGAV
631
NPLLS
636
QAESS
641
HTEPD
646
LEDCS
651
FRCRG
656
TSPQE
661
SLSSM
666
SPISS
671
LPALF
676
DQTAS
681
APCGG
686
GQLDP
691
AAPGT
696
TNMEQ
701
LLEKQ
706
GDGEA
711
GVNIV
716
EMLKA
721
LHALQ
726
KENQR
731
LQEQI
736
LSLTA
741
KKERL
746
QILNV
751
QLSVP
756
FPALP
761
AALPA
766
ANGPV
771
PGPYG
776
LPPQA
781
GSSDS
786
LSTSK
791
SPPGK
796
SSLGL
801
DNSLS
806
TSSED
811
PHSGC
816
PSRSS
821
SSLSF
826
HSTPP
831
PLPLL
836
QQSPA
841
TLPLA
846
LPGAP
851
APLPP
856
QPQNG
861
LGRAP
866
GAAGL
871
GAMPM
876
AEGLL
881
GGLAG
886
SGGLP
891
LNGLL
896
GGLNG
901
AAAPN
906
PASLS
911
QAGGA
916
PTLQL
921
PGCLN
926
SLTEQ
931
QRHLL
936
QQQEQ
941
QLQQL
946
QQLLA
951
SPQLT
956
PEHQT
961
VVYQM
966
IQQIQ
971
QKREL
976
QRLQM
981
AGGSQ
986
LPMAS
991
LLAGS
996
STPLL
1001
SAGTP
1006
GLLPT
1011
ASAPP
1016
LLPAG
1021
ALVAP
1026
SLGNN
1031
TSLMA
1036
AAAAA
1041
AAVAA
1046
AGGPP
1051
VLTAQ
1056
TNPFL
1061
SLSGA
1066
EGSGG
1071
GPKGG
1076
TADKG
1081
ASANQ
1086
EKG
1091
Mutation Information
DNA mutation:
None
Peptide Range:
545 ~ 569
Mut AA position:
557 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPLLGAGIYTSNKDPISHSGGMLRA
||||||||||||.||||||||||||
Mutant:
SPLLGAGIYTSNEDPISHSGGMLRA"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) MLLT6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay