Immunogenicity 12676
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PLEKHM1
Transcript ID
uc010wjn.1
HLA INFO
C*03:03
TCR INFO
No TCR info found!
Full length protein sequence (923 aa)
MVECF
1
ESGGT
6
RLSLS
11
SFNVS
16
CDSLR
21
EQLRE
26
WRCFQ
31
WWRMD
36
WTPRL
41
PSRHI
46
ISELE
51
HLTFV
56
NTDVG
61
RCRAW
66
LRLAL
71
NDGLM
76
ECYLK
81
LLLQE
86
QARLH
91
EYYQP
96
TALLR
101
DAEEG
106
EFLLS
111
FLQGL
116
TSLSF
121
ELSYK
126
SAILN
131
EWTLT
136
PLALS
141
GLCPL
146
SELDP
151
LSTSG
156
AELQR
161
KESLD
166
SISHS
171
SGSED
176
IEVHH
181
SGHKI
186
RRNQK
191
LTASS
196
LSLDT
201
ASSSQ
206
LSCSL
211
NSDSC
216
LLQEN
221
GSKSP
226
DHCEE
231
PMSCD
236
SDLGT
241
ANAED
246
SDRSL
251
QEVLL
256
EFSKA
261
QVNSV
266
PTNGL
271
SQETE
276
IPTPQ
281
ASLSL
286
HGLNT
291
STYLH
296
CEAPA
301
EPLPA
306
QAASG
311
TQDGV
316
HVQEP
321
RPQAP
326
SPLDL
331
QQPVE
336
STSGQ
341
QPSST
346
VSETA
351
REVGQ
356
GNGLQ
361
KAQAH
366
DGAGL
371
KLVVS
376
SPTSP
381
KNKSW
386
ISEDD
391
FYRPS
396
REQPL
401
ESASD
406
HPIAS
411
YRGTP
416
GSRPG
421
LHRHF
426
SQEPR
431
KNCSL
436
GALDQ
441
ACVPS
446
PGRRQ
451
AQAAP
456
SQGHK
461
SFRVV
466
HRRQM
471
GLSNP
476
FRGLM
481
KLGTV
486
ERRGA
491
MGIWK
496
ELFCE
501
LSPLE
506
FRLYL
511
SNEEH
516
TCVEN
521
CSLLR
526
CESVG
531
PAHSD
536
GRFEL
541
VFSGK
546
KLALR
551
ASSQD
556
EAEDW
561
LDRVR
566
EALQK
571
VRPQQ
576
EDEWV
581
NVQYP
586
DQPEE
591
PPEAP
596
QGCLS
601
PSDLL
606
SEPAA
611
LQGTQ
616
FDWSS
621
AQVPE
626
PDAIK
631
ESLLY
636
LYMDR
641
TWMPY
646
IFSLS
651
LEALK
656
CFRIR
661
NNEKM
666
LSDSH
671
GVETI
676
RDILP
681
DTSLG
686
GPSFF
691
KIITA
696
KAVLK
701
LQAGN
706
AEEAA
711
LWRDL
716
VRKVL
721
ASYLE
726
TAEEA
731
VTLGG
736
SLDEN
741
CQEVL
746
KFATR
751
ENGFL
756
LQYLV
761
AIPME
766
KGLDS
771
QGCFC
776
AGCSR
781
QIGFS
786
FVRPK
791
LCAFS
796
GLYYC
801
DICHQ
806
DDASV
811
IPARI
816
IHNWD
821
LTKRP
826
ICRQA
831
LKFLT
836
QIRAQ
841
PLINL
846
QMVNA
851
SLYEH
856
VERMH
861
LIGRR
866
REQLK
871
LLGDY
876
LGLCR
881
SGALK
886
ELSKR
891
LNHRN
896
YLLES
901
PHRFS
906
VADLQ
911
QIADG
916
VYE
921
Mutation Information
DNA mutation:
None
Peptide Range:
518 ~ 542
Mut AA position:
530 (13 in Wild Type peptide)
Alignment
Wild Type:
"EEHTCVENCSLLRCESVGPAHSDGR
||||||||||||.||||||||||||
Mutant:
EEHTCVENCSLLCCESVGPAHSDGR"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) PLEKHM1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
COS7
Assay
IFNg ELISPOT assay