Immunogenicity 127
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PREP
Transcript ID
uc003prc.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (492 aa)
MLSLQ
1
YPDVY
6
RDETA
11
VQDYH
16
GHKIC
21
DPYAW
26
LEDPD
31
SEQTK
36
AFVEA
41
QNKIT
46
VPFLE
51
QCPIR
56
GLYKE
61
RMTEL
66
YDYPK
71
YSCHF
76
KKGKR
81
YFYFY
86
NTGLQ
91
NQRVL
96
YVQDS
101
LEGEA
106
RVFLD
111
PNILS
116
DDGTV
121
ALRGY
126
AFSED
131
GEYFA
136
YGLSA
141
SGSDW
146
VTIKF
151
MKVDG
156
AKELP
161
DVLER
166
VKFSC
171
MAWTH
176
DGKGM
181
FYNSY
186
PQQDG
191
KSDGT
196
ETSTN
201
LHQKL
206
YYHVL
211
GTDQS
216
EDILC
221
AEFPD
226
EPKWM
231
GGAEL
236
SDDGR
241
YVLLS
246
IREGC
251
DPVNR
256
LWYCD
261
LQQES
266
SGIAG
271
ILKWV
276
KLIDN
281
FEGEY
286
DYVTN
291
EGTVF
296
TFKTN
301
RQSPN
306
YRVIN
311
IDFRD
316
PEESK
321
WKVLV
326
PEHEK
331
DVLEW
336
IACVR
341
SNFLV
346
LCYLH
351
DVKNI
356
LQLHD
361
LTTGA
366
LLKTF
371
PLDVG
376
SIVGY
381
SGQKK
386
DTEIF
391
YQFTS
396
FLSPG
401
IIYHC
406
DLTKE
411
ELEPR
416
VFREV
421
TVKGI
426
DASDY
431
QTVQI
436
PRFLK
441
TEGLK
446
QPCVE
451
QVCYH
456
HFPNS
461
MCSVR
466
VCHIL
471
IILTM
476
FQAFS
481
LLHHS
486
EL
491
Mutation Information
DNA mutation:
c.C58T
Peptide Range:
8 ~ 32
Mut AA position:
20 (13 in Wild Type peptide)
Alignment
Wild Type:
"DVYRDETAVQDYHGHKICDPYAWLE
||||||||||||.||||||||||||
Mutant:
DVYRDETAVQDYYGHKICDPYAWLE"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) PREP
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
DVYRDETAVQDYYGHKICDPYAWLE
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT