Immunogenicity 12751

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SERPINB3
Transcript ID
uc002lji.3
HLA INFO
C*03:03
TCR INFO

No TCR info found!

T cell Tumor cell C*03:03
sequence
Full length protein sequence (390 aa)
MNSLS
1
EANTK
6
FMFDL
11
FQQFR
16
KSKEN
21
NIFYS
26
PISIT
31
SALGM
36
VLLGA
41
KDNTA
46
QQIKK
51
VLHFD
56
QVTEN
61
TTGKA
66
ATYHV
71
DRSGN
76
VHHQF
81
QKLLT
86
EFNKS
91
TDAYE
96
LKIAN
101
KLFGE
106
KTYLF
111
LQEYL
116
DAIKK
121
FYQTS
126
VESVD
131
FANAP
136
EESRK
141
KINSW
146
VESQT
151
NEKIK
156
NLIPE
161
GNIGS
166
NTTLV
171
LVNAI
176
YFKGQ
181
WEKKF
186
NKEDT
191
KEEKF
196
WPNKN
201
TYKSI
206
QMMRQ
211
YTSFH
216
FASLE
221
DVQAK
226
VLEIP
231
YKGKD
236
LSMIV
241
LLPNE
246
IDGLQ
251
KLEEK
256
LTAEK
261
LMEWT
266
SLQNM
271
RETRV
276
DLHLP
281
RFKVE
286
ESYDL
291
KDTLR
296
TMGMV
301
DIFNG
306
DADLS
311
GMTGS
316
RGLVL
321
SGVLH
326
KAFVE
331
VTEEG
336
AEAAA
341
ATAVV
346
GFGSS
351
PTSTN
356
EEFHC
361
NHPFL
366
FFIRQ
371
NKTNS
376
ILFYG
381
RFSSP
386
Mutation Information
DNA mutation:
None
Peptide Range:
238 ~ 262
Mut AA position:
250 (13 in Wild Type peptide)
Alignment
Wild Type:
"GKDLSMIVLLPNEIDGLQKLEEKLT
||||||||||||.||||||||||||
Mutant:
GKDLSMIVLLPNKIDGLQKLEEKLT"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay