Immunogenicity 12780
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PIAS4
Transcript ID
uc002lzg.3
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (510 aa)
MAAEL
1
VEAKN
6
MVMSF
11
RVSDL
16
QMLLG
21
FVGRS
26
KSGLK
31
HELVT
36
RALQL
41
VQFDC
46
SPELF
51
KKIKE
56
LYETR
61
YAKKN
66
SEPAP
71
QPHRP
76
LDPLT
81
MHSTY
86
DRAGA
91
VPRTP
96
LAGPN
101
IDYPV
106
LYGKY
111
LNGLG
116
RLPAK
121
TLKPE
126
VRLVK
131
LPFFN
136
MLDEL
141
LKPTE
146
LVPQN
151
NEKLQ
156
ESPCI
161
FALTP
166
RQVEL
171
IRNSR
176
ELQPG
181
VKAVQ
186
VVLRI
191
CYSDT
196
SCPQE
201
DQYPP
206
NIAVK
211
VNHSY
216
CSVPG
221
YYPSN
226
KPGVE
231
PKRPC
236
RPINL
241
THLMY
246
LSSAT
251
NRITV
256
TWGNY
261
GKSYS
266
VALYL
271
VRQLT
276
SSELL
281
QRLKT
286
IGVKH
291
PELCK
296
ALVKE
301
KLRLD
306
PDSEI
311
ATTGV
316
RVSLI
321
CPLVK
326
MRLSV
331
PCRAE
336
TCAHL
341
QCFDA
346
VFYLQ
351
MNEKK
356
PTWMC
361
PVCDK
366
PAPYD
371
QLIID
376
GLLSK
381
ILSEC
386
EDADE
391
IEYLV
396
DGSWC
401
PIRAE
406
KERSC
411
SPQGA
416
ILVLG
421
PSDAN
426
GLLPA
431
PSVNG
436
SGALG
441
STGGG
446
GPVGS
451
MENGK
456
PGADV
461
VDLTL
466
DSSSS
471
SEDEE
476
EEEEE
481
EEDED
486
EEGPR
491
PKRRC
496
PFQKG
501
LVPAC
506
Mutation Information
DNA mutation:
None
Peptide Range:
210 ~ 234
Mut AA position:
222 (13 in Wild Type peptide)
Alignment
Wild Type:
"PNIAVKVNHSYCSVPGYYPSNKPGV
||||||||||||.||||||||||||
Mutant:
PNIAVKVNHSYCFVPGYYPSNKPGV"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) PIAS4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay