Immunogenicity 12803

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZNF653
Transcript ID
uc002mrz.2
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (615 aa)
MAERA
1
LEPEA
6
EAEAE
11
AGAGG
16
EAAAE
21
EGAAG
26
RKARG
31
RPRLT
36
ESDRA
41
RRRLE
46
SRKKY
51
DVRRV
56
YLGEA
61
HGPWV
66
DLRRR
71
SGWSD
76
AKLAA
81
YLISL
86
ERGQR
91
SGRHG
96
KPWEQ
101
VPKKP
106
KRKKR
111
RRRNV
116
NCLKN
121
VVIWY
126
EDHKH
131
RCPYE
136
PHLAE
141
LDPTF
146
GLYTT
151
AVWQC
156
EAGHR
161
YFQDL
166
HSPLK
171
PLSDS
176
DPDSD
181
KVGNG
186
LVAGS
191
SDSSS
196
SGSAS
201
DSEES
206
PEGQP
211
VKAAA
216
AAAAA
221
TPTSP
226
VGSSG
231
LITQE
236
GVHIP
241
FDVHH
246
VESLA
251
EQGTP
256
LCSNP
261
AGNGP
266
EALET
271
VVCVP
276
VPVQV
281
GAGPS
286
ALFEN
291
VPQEA
296
LGEVV
301
ASCPM
306
PGMVP
311
GSQVI
316
IIAGP
321
GYDAL
326
TAEGI
331
HLNMA
336
AGSGV
341
PGSGL
346
GEEVP
351
CAMME
356
GVAAY
361
TQTEP
366
EGSQP
371
STMDA
376
TAVAG
381
IETKK
386
EKEDL
391
CLLKK
396
EEKEE
401
PVAPE
406
LATTV
411
PESAE
416
PEAEA
421
DGEEL
426
DGSDM
431
SAIIY
436
EIPKE
441
PEKRR
446
RSKRS
451
RVMDA
456
DGLLE
461
MFHCP
466
YEGCS
471
QVYVA
476
LSSFQ
481
NHVNL
486
VHRKG
491
KTKVC
496
PHPGC
501
GKKFY
506
LSNHL
511
RRHMI
516
IHSGV
521
REFTC
526
ETCGK
531
SFKRK
536
NHLEV
541
HRRTH
546
TGETP
551
LQCEI
556
CGYQC
561
RQRAS
566
LNWHM
571
KKHTA
576
EVQYN
581
FTCDR
586
CGKRF
591
EKLDS
596
VKFHT
601
LKSHP
606
DHKPT
611
Mutation Information
DNA mutation:
None
Peptide Range:
489 ~ 513
Mut AA position:
501 (13 in Wild Type peptide)
Alignment
Wild Type:
"NLVHRKGKTKVCPHPGCGKKFYLSN
||||||||||||.||||||||||||
Mutant:
NLVHRKGKTKVCFHPGCGKKFYLSN"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay