Immunogenicity 1286

Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ZNF724
Transcript ID
ENST00000418100

HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
Full length protein sequence (619 aa)
MGPLT
1
FMDVA
6
IEFSV
11
EEWQC
16
LDTAQ
21
QNLYR
26
NVMLE
31
NYRNL
36
VFLGI
41
AVSKP
46
DLITC
51
LEQGK
56
EPWNM
61
ERHEM
66
VAKPP
71
GMCCY
76
FAQDL
81
RPEQS
86
IKASL
91
QRIIL
96
RKYEK
101
CGHHN
106
LQLKK
111
GYKSV
116
DEYKV
121
HKGSY
126
NGFNQ
131
CLTTT
136
QSKIF
141
QCDKY
146
VKDFH
151
KFSNS
156
NRHKT
161
EKNPF
166
KCKEC
171
GKSFC
176
VLSHL
181
TQHKR
186
IHTTV
191
NSYKL
196
EECGK
201
AFNVS
206
STLSQ
211
HKRIH
216
TGQKH
221
YKCEE
226
CGIAF
231
NKSSH
236
LNTHK
241
IIHTG
246
EKSYK
251
REECG
256
KAFNI
261
SSHLT
266
THKII
271
HTGEN
276
AYKCK
281
ECGKA
286
FNQSS
291
TLTRH
296
KIIHA
301
GEKPY
306
ICEHC
311
GRAFN
316
QSSNL
321
TKHKR
326
IHTGD
331
KPYKC
336
EECGK
341
AFNVS
346
STLTQ
351
HKRIH
356
TGEKP
361
YKCEE
366
CGKAF
371
NVSST
376
LTQHK
381
RIHTG
386
EKPYK
391
CEECG
396
KAFNT
401
SSHLT
406
THKRI
411
HTGEK
416
PYKCE
421
ECGKA
426
FNQFS
431
QLTTH
436
KIIHT
441
GEKPY
446
KCKEC
451
GKAFK
456
RSSNL
461
TEHRI
466
IHTGE
471
KPYKC
476
EECGK
481
AFNLS
486
SHLTT
491
HKKIH
496
TGEKP
501
YKCKE
506
CGKAF
511
NQSST
516
LARHK
521
IIHAG
526
EKPYK
531
CEECG
536
KAFYQ
541
YSNLT
546
QHKII
551
HTGEK
556
PYKCE
561
ECGKA
566
FNWSS
571
TLTKH
576
KVIHT
581
GEKPY
586
KCKEC
591
GKAFN
596
QCSNL
601
TTHKK
606
IHAVE
611
KSDK
616
Mutation Information
DNA mutation:
None
Peptide Range:
347 ~ 371
Mut AA position:
359 (13 in Wild Type peptide)
Alignment
Wild Type:
"FNVSSTLTQHKRIHTGEKPYKCEEC
||||||||||||.||||||||||||
Mutant:
FNVSSTLTQHKRVHTGEKPYKCEEC"

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000196081

Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay