Immunogenicity 12934

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZNF586
Transcript ID
uc010euh.3
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (359 aa)
MLETL
1
TLISS
6
LGCWH
11
GGEDE
16
AAPSK
21
QSTCI
26
HIYKD
31
QGGHS
36
GERPY
41
ECGEY
46
RKLFK
51
NKSCL
56
TEPRR
61
DHKHR
66
NVRTG
71
ERPYE
76
CSKYG
81
KLFHQ
86
KPTLH
91
IHERF
96
HTGQK
101
TYECS
106
ECGKS
111
FHQSS
116
SLLQR
121
QTLHT
126
RERPY
131
ECIEC
136
GKAFA
141
EKSSL
146
INHRK
151
VHSGA
156
KRYEC
161
NECGK
166
SFAYT
171
SSLIK
176
HRRIH
181
TGERP
186
YECSE
191
CGRSF
196
AENSS
201
LIKHL
206
RVHTG
211
ERPYE
216
CVECG
221
KSFRR
226
SSSLL
231
QHQRV
236
HTRER
241
PYECS
246
ECGKS
251
FSLRS
256
NLIHH
261
QRVHT
266
GERHE
271
CGQCG
276
KSFSR
281
KSSLI
286
IHLRV
291
HTGER
296
PYECS
301
DCGKS
306
FAENS
311
SLIKH
316
LRVHT
321
GERPY
326
ECIDC
331
GKSFR
336
HSSSF
341
RRHQR
346
VHTGM
351
RPYK
356
Mutation Information
DNA mutation:
None
Peptide Range:
174 ~ 198
Mut AA position:
186 (13 in Wild Type peptide)
Alignment
Wild Type:
"YTSSLIKHRRIHTGERPYECSECGR
||||||||||||.||||||||||||
Mutant:
YTSSLIKHRRIHIGERPYECSECGR"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay