Immunogenicity 13068
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CPS1
Transcript ID
uc010fus.3
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (1049 aa)
MKEEN
1
VKTVL
6
MNPNI
11
ASVQT
16
NEVGL
21
KQADT
26
VYFLP
31
ITPQF
36
VTEVI
41
KAEQP
46
DGLIL
51
GMGGQ
56
TALNC
61
GVELF
66
KRGVL
71
KEYGV
76
KVLGT
81
SVESI
86
MATED
91
RQLFS
96
DKLNE
101
INEKI
106
APSFA
111
VESIE
116
DALKA
121
ADTIG
126
YPVMI
131
RSAYA
136
LGGLG
141
SGICP
146
NRETL
151
MDLST
156
KAFAM
161
TNQIL
166
VEKSV
171
TGWKE
176
IEYEV
181
VRDAD
186
DNCVT
191
VCNME
196
NVDAM
201
GVHTG
206
DSVVV
211
APAQT
216
LSNAE
221
FQMLR
226
RTSIN
231
VVRHL
236
GIVGE
241
CNIQF
246
ALHPT
251
SMEYC
256
IIEVN
261
ARLSR
266
SSALA
271
SKATG
276
YPLAF
281
IAAKI
286
ALGIP
291
LPEIK
296
NVVSG
301
KTSAC
306
FEPSL
311
DYMVT
316
KIPRW
321
DLDRF
326
HGTSS
331
RIGSS
336
MKSVG
341
EVMAI
346
GRTFE
351
ESFQK
356
ALRMC
361
HPSIE
366
GFTPR
371
LPMNK
376
EWPSN
381
LDLRK
386
ELSEP
391
SSTRI
396
YAIAK
401
AIDDN
406
MSLDE
411
IEKLT
416
YIDKW
421
FLYKM
426
RDILN
431
MEKTL
436
KGLNS
441
ESMTE
446
ETLKR
451
AKEIG
456
FSDKQ
461
ISKCL
466
GLTEA
471
QTREL
476
RLKKN
481
IHPWV
486
KQIDT
491
LAAEY
496
PSVTN
501
YLYVT
506
YNGQE
511
HDVNF
516
DDHGM
521
MVLGC
526
GPYHI
531
GSSVE
536
FDWCA
541
VSSIR
546
TLRQL
551
GKKTV
556
VVNCN
561
PETVS
566
TDFDE
571
CDKLY
576
FEELS
581
LERIL
586
DIYHQ
591
EACGG
596
CIISV
601
GGQIP
606
NNLAV
611
PLYKN
616
GVKIM
621
GTSPL
626
QIDRA
631
EDRSI
636
FSAVL
641
DELKV
646
AQAPW
651
KAVNT
656
LNEAL
661
EFAKS
666
VDYPC
671
LLRPS
676
YVLSG
681
SAMNV
686
VFSED
691
EMKKF
696
LEEAT
701
RVSQE
706
HPVVL
711
TKFVE
716
GAREV
721
EMDAV
726
GKDGR
731
VISHA
736
ISEHV
741
EDAGV
746
HSGDA
751
TLMLP
756
TQTIS
761
QGAIE
766
KVKDA
771
TRKIA
776
KAFAI
781
SGPFN
786
VQFLV
791
KGNDV
796
LVIEC
801
NLRAS
806
RSFPF
811
VSKTL
816
GVDFI
821
DVATK
826
VMIGE
831
NVDEK
836
HLPTL
841
DHPII
846
PADYV
851
AIKAP
856
MFSWP
861
RLRDA
866
DPILR
871
CEMAS
876
TGEVA
881
CFGEG
886
IHTAF
891
LKAML
896
STGFK
901
IPQKG
906
ILIGI
911
QQSFR
916
PRFLG
921
VAEQL
926
HNEGF
931
KLFAT
936
EATSD
941
WLNAN
946
NVPAT
951
PVAWP
956
SQEGQ
961
NPSLS
966
SIRKL
971
IRDGS
976
IDLVI
981
NLPNN
986
NTKFV
991
HDNYV
996
IRRTA
1001
VDSGI
1006
PLLTN
1011
FQVTK
1016
LFAEA
1021
VQKSR
1026
KVDSK
1031
SLFHY
1036
RQYSA
1041
GKAA
1046
Mutation Information
DNA mutation:
None
Peptide Range:
268 ~ 292
Mut AA position:
731 (13 in Wild Type peptide)
Alignment
Wild Type:
"LSRSSALASKATGYPLAFIAAKIAL
||||||||||||.||||||||||||
Mutant:
LSRSSALASKATSYPLAFIAAKIAL"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CPS1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay