Immunogenicity 131

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
AKAP9
Transcript ID
uc003uli.3
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (3968 aa)
MEDEE
1
RQKKL
6
EAGKA
11
KLAQF
16
RQRKA
21
QSDGQ
26
SPSKK
31
QKKKR
36
KTSSS
41
KHDVS
46
AHHDL
51
NIDQS
56
QCNEM
61
YINSS
66
QRVES
71
TVIPE
76
STIMR
81
TLHSG
86
EITSH
91
EQGFS
96
VELES
101
EISTT
106
ADDCS
111
SEVNG
116
CSFVM
121
RTGKP
126
TNLLR
131
EEEFG
136
VDDSY
141
SEQGA
146
QDSPT
151
HLEMM
156
ESELA
161
GKQHE
166
IEELN
171
RELEE
176
MRVTY
181
GTEGL
186
QQLQE
191
FEAAI
196
KQRDG
201
IITQL
206
TANLQ
211
QARRE
216
KDETM
221
REFLE
226
LTEQS
231
QKLQI
236
QFQQL
241
QASET
246
LRNST
251
HSSTA
256
ADLLQ
261
AKQQI
266
LTHQQ
271
QLEEQ
276
DHLLE
281
DYQKK
286
KEDFT
291
MQISF
296
LQEKI
301
KVYEM
306
EQDKK
311
VENSN
316
KEEIQ
321
EKETI
326
IEELN
331
TKIIE
336
EEKKT
341
LELKD
346
KLTTA
351
DKLLG
356
ELQEQ
361
IVQKN
366
QEIKN
371
MKLEL
376
TNSKQ
381
KERQS
386
SEEIK
391
QLMGT
396
VEELQ
401
KRNHK
406
DSQFE
411
TDIVQ
416
RMEQE
421
TQRKL
426
EQLRA
431
ELDEM
436
YGQQI
441
VQMKQ
446
ELIRQ
451
HMAQM
456
EEMKT
461
RHKGE
466
MENAL
471
RSYSN
476
ITVNE
481
DQIKL
486
MNVAI
491
NELNI
496
KLQDT
501
NSQKE
506
KLKEE
511
LGLIL
516
EEKCA
521
LQRQL
526
EDLVE
531
ELSFS
536
REQIQ
541
RARQT
546
IAEQE
551
SKLNE
556
AHKSL
561
STVED
566
LKAEI
571
VSASE
576
SRKEL
581
ELKHE
586
AEVTN
591
YKIKL
596
EMLEK
601
EKNAV
606
LDRMA
611
ESQEA
616
ELERL
621
RTQLL
626
FSHEE
631
ELSKL
636
KEDLE
641
IEHRI
646
NIEKL
651
KDNLG
656
IHYKQ
661
QIDGL
666
QNEMS
671
QKIET
676
MQFEK
681
DNLIT
686
KQNQL
691
ILEIS
696
KLKDL
701
QQSLV
706
NSKSE
711
EMTLQ
716
INELQ
721
KEIEI
726
LRQEE
731
KEKGT
736
LEQEV
741
QELQL
746
KTELL
751
EKQMK
756
EKEND
761
LQEKF
766
AQLEA
771
ENSIL
776
KDEKK
781
TLEDM
786
LKIHT
791
PVSQE
796
ERLIF
801
LDSIK
806
SKSKD
811
SVWEK
816
EIEIL
821
IEENE
826
DLKQQ
831
CIQLN
836
EEIEK
841
QRNTF
846
SFAEK
851
NFEVN
856
YQELQ
861
EEYAC
866
LLKVK
871
DDLED
876
SKNKQ
881
ELEYK
886
SKLKA
891
LNEEL
896
HLQRI
901
NPTTV
906
KMKSS
911
VFDED
916
KTFVA
921
ETLEM
926
GEVVE
931
KDTTE
936
LMEKL
941
EVTKR
946
EKLEL
951
SQRLS
956
DLSEQ
961
LKQKH
966
GEISF
971
LNEEV
976
KSLKQ
981
EKEQV
986
SLRCR
991
ELEII
996
INHNR
1001
AENVQ
1006
SCDTQ
1011
VSSLL
1016
DGVVT
1021
MTSRG
1026
AEGSV
1031
SKVNK
1036
SFGEE
1041
SKIMV
1046
EDKVS
1051
FENMT
1056
VGEES
1061
KQEQL
1066
ILDHL
1071
PSVTK
1076
ESSLR
1081
ATQPS
1086
ENDKL
1091
QKELN
1096
VLKSE
1101
QNDLR
1106
LQMEA
1111
QRICL
1116
SLVYS
1121
THVDQ
1126
VREYM
1131
ENEKD
1136
KALCS
1141
LKEEL
1146
IFAQE
1151
EKIKE
1156
LQKIH
1161
QLELQ
1166
TMKTQ
1171
ETGDE
1176
GKPLH
1181
LLIGK
1186
LQKAV
1191
SEECS
1196
YFLQT
1201
LCSVL
1206
GEYYT
1211
PALKC
1216
EVNAE
1221
DKENS
1226
GDYIS
1231
ENEDP
1236
ELQDY
1241
RYEVQ
1246
DFQEN
1251
MHTLL
1256
NKVTE
1261
EYNKL
1266
LVLQT
1271
RLSKI
1276
WGQQT
1281
DGMKL
1286
EFGEE
1291
NLPKE
1296
ETEFL
1301
SIHSQ
1306
MTNLE
1311
DIDVN
1316
HKSKL
1321
SSLQD
1326
LEKTK
1331
LEEQV
1336
QELES
1341
LISSL
1346
QQQLK
1351
ETEQN
1356
YEAEI
1361
HCLQK
1366
RLQAV
1371
SESTV
1376
PPSLP
1381
VDSVV
1386
ITESD
1391
AQRTM
1396
YPGSC
1401
VKKNI
1406
DGTIE
1411
FSGEF
1416
GVKEE
1421
TNIVK
1426
LLEKQ
1431
YQEQL
1436
EEEVA
1441
KVIVS
1446
MSIAF
1451
AQQTE
1456
LSRIS
1461
GGKEN
1466
TASSK
1471
QAHAV
1476
CQQEQ
1481
HYFNE
1486
MKLSQ
1491
DQIGF
1496
QTFET
1501
VDVKF
1506
KEEFK
1511
PLSKE
1516
LGEHG
1521
KEILL
1526
SNSDP
1531
HDIPE
1536
SKDCV
1541
LTISE
1546
EMFSK
1551
DKTFI
1556
VRQSI
1561
HDEIS
1566
VSSMD
1571
ASRQL
1576
MLNEE
1581
QLEDM
1586
RQELV
1591
RQYQE
1596
HQQAT
1601
ELLRQ
1606
AHMRQ
1611
MERQR
1616
EDQEQ
1621
LQEEI
1626
KRLNR
1631
QLAQR
1636
SSIDN
1641
ENLVS
1646
ERERV
1651
LLEEL
1656
EALKQ
1661
LSLAG
1666
REKLC
1671
CELRN
1676
SSTQT
1681
QNGNE
1686
NQGEV
1691
EEQTF
1696
KEKEL
1701
DRKPE
1706
DVPPE
1711
ILSNE
1716
SLHGG
1721
IWPLR
1726
FWLPH
1731
WIISM
1736
ERSQY
1741
GTQTR
1746
KTVYA
1751
LQKAN
1756
NRLLK
1761
ILLEV
1766
VKTTA
1771
AVEET
1776
IGRHV
1781
LGILD
1786
RSSKS
1791
QSSAS
1796
LIWRS
1801
EAEAS
1806
VKSCV
1811
HEEHT
1816
RVTDE
1821
SIPSY
1826
SGSDM
1831
PRNDI
1836
NMWSK
1841
VTEEG
1846
TELSQ
1851
RLVRS
1856
GFAGT
1861
EIDPE
1866
NEELM
1871
LNISS
1876
RLQAA
1881
VEKLL
1886
EAISE
1891
TSSQL
1896
EHAKV
1901
TQTEL
1906
MRESF
1911
RQKQE
1916
ATESL
1921
KCQEE
1926
LRERL
1931
HEESR
1936
AREQL
1941
AVELS
1946
KAEGV
1951
IDGYA
1956
DEKTL
1961
FERQI
1966
QEKTD
1971
IIDRL
1976
EQELL
1981
CASNR
1986
LQELE
1991
AEQQQ
1996
IQEER
2001
ELLSR
2006
QKEAM
2011
KAEAG
2016
PVEQR
2021
LVDAA
2026
VDAAP
2031
GAELL
2036
QETEK
2041
LMKEK
2046
LEVQC
2051
QAEKV
2056
RDDLQ
2061
KQVKA
2066
LEIDV
2071
EEQVS
2076
RFIEL
2081
EQEKN
2086
TELMD
2091
LRQQN
2096
QALEK
2101
QLEKM
2106
RKFLD
2111
EQAID
2116
REHER
2121
DVFQQ
2126
EIQKL
2131
EQQLK
2136
VVPRF
2141
QPISE
2146
HQTRE
2151
VEQLA
2156
NHLKE
2161
KTDKC
2166
SELLL
2171
SKEQL
2176
QRDIQ
2181
ERNEE
2186
IEKLE
2191
FRVRE
2196
LEQAL
2201
LVSAD
2206
TFQKV
2211
EDRKH
2216
FGAVE
2221
AKPEL
2226
SLEVQ
2231
LQAER
2236
DAIDR
2241
KEKEI
2246
TNLEE
2251
QLEQF
2256
REELE
2261
NKNEE
2266
VQQLH
2271
MQLEI
2276
QKKES
2281
TTRLQ
2286
ELEQE
2291
NKLFK
2296
DDMEK
2301
LGLAI
2306
KESDA
2311
MSTQD
2316
QHVLF
2321
GKFAQ
2326
IIQEK
2331
EVEID
2336
QLNEQ
2341
VTKLQ
2346
QQLKI
2351
TTDNK
2356
VIEEK
2361
NELIR
2366
DLETQ
2371
IECLM
2376
SDQEC
2381
VKRNR
2386
EEEIE
2391
QLNEV
2396
IEKLQ
2401
QELAN
2406
IGQKT
2411
SMNAH
2416
SLSEE
2421
ADSLK
2426
HQLDV
2431
VIAEK
2436
LALEQ
2441
QVETA
2446
NEEMT
2451
FMKNV
2456
LKETN
2461
FKMNQ
2466
LTQEL
2471
FSLKR
2476
ERESV
2481
EKIQS
2486
IPENS
2491
VNVAI
2496
DHLSK
2501
DKPEL
2506
EVVLT
2511
EDALK
2516
SLENQ
2521
TYFKS
2526
FEENG
2531
KGSII
2536
NLETR
2541
LLQLE
2546
STVSA
2551
KDLEL
2556
TQCYK
2561
QIKDM
2566
QEQGQ
2571
FETEM
2576
LQKKI
2581
VNLQK
2586
IVEEK
2591
VAAAL
2596
VSQIQ
2601
LEAVQ
2606
EYAKF
2611
CQDNQ
2616
TISSE
2621
PERTN
2626
IQNLN
2631
QLRED
2636
ELGSD
2641
ISALT
2646
LRISE
2651
LESQV
2656
VEMHT
2661
SLILE
2666
KEQVE
2671
IAEKN
2676
VLEKE
2681
KKLLE
2686
LQKLL
2691
EGNEK
2696
KQREK
2701
EKKRS
2706
PQDVE
2711
VLKTT
2716
TELFH
2721
SNEES
2726
GFFNE
2731
LEALR
2736
AESVA
2741
TKAEL
2746
ASYKE
2751
KAEKL
2756
QEELL
2761
VKETN
2766
MTSLQ
2771
KDLSQ
2776
VRDHL
2781
AEAKE
2786
KLSIL
2791
EKEDE
2796
TEVQE
2801
SKKAC
2806
MFEPL
2811
PIKLS
2816
KSIAS
2821
QTDGT
2826
LKISS
2831
SNQTP
2836
QILVK
2841
NAGIQ
2846
INLQS
2851
ECSSE
2856
EVTEI
2861
ISQFT
2866
EKIEK
2871
MQELH
2876
AAEIL
2881
DMESR
2886
HISET
2891
ETLKR
2896
EHYVA
2901
VQLLK
2906
EECGT
2911
LKAVI
2916
QCLRS
2921
KEGSS
2926
IPELA
2931
HSDAY
2936
QTREI
2941
CSSDS
2946
GSDWG
2951
QGIYL
2956
THSQG
2961
FDIAS
2966
EGRGE
2971
ESESA
2976
TDSFP
2981
KKIKG
2986
LLRAV
2991
HNEGM
2996
QVLSL
3001
TESPY
3006
SDGED
3011
HSIQQ
3016
VSEPW
3021
LEERK
3026
AYINT
3031
ISSLK
3036
DLITK
3041
MQLQR
3046
EAEVY
3051
DSSQS
3056
HESFS
3061
DWRGE
3066
LLLAL
3071
QQVFL
3076
EERSV
3081
LLAAF
3086
RTELT
3091
ALGTT
3096
DAVGL
3101
LNCLE
3106
QRIQE
3111
QGVEY
3116
QAAME
3121
CLQKA
3126
DRRSL
3131
LSEIQ
3136
ALHAQ
3141
MNGRK
3146
ITLKR
3151
EQESE
3156
KPSQE
3161
LLEYN
3166
IQQKQ
3171
SQMLE
3176
MQVEL
3181
SSMKD
3186
RATEL
3191
QEQLS
3196
SEKMV
3201
VAELK
3206
SELAQ
3211
TKLEL
3216
ETTLK
3221
AQHKH
3226
LKELE
3231
AFRLE
3236
VKDKT
3241
DEVHL
3246
LNDTL
3251
ASEQK
3256
KSREL
3261
QWALE
3266
KEKAK
3271
LGRSE
3276
ERDKE
3281
ELEDL
3286
KFSLE
3291
SQKQR
3296
NLQLN
3301
LLLEQ
3306
QKQLL
3311
NESQQ
3316
KIESQ
3321
RMLYD
3326
AQLSE
3331
EQGRN
3336
LELQV
3341
LLESE
3346
KVRIR
3351
EMSST
3356
LDRER
3361
ELHAQ
3366
LQSSD
3371
GTGQS
3376
RPPLP
3381
SEDLL
3386
KELQK
3391
QLEEK
3396
HSRIV
3401
ELLNE
3406
TEKYK
3411
LDSLQ
3416
TRQQM
3421
EKDRQ
3426
VHRKT
3431
LQTEQ
3436
EANTE
3441
GQKKM
3446
HELQS
3451
KVEDL
3456
QRQLE
3461
EKRQQ
3466
VYKLD
3471
LEGQR
3476
LQGIM
3481
QEFQK
3486
QELER
3491
EEKRE
3496
SRRIL
3501
YQNLN
3506
EPTTW
3511
SLTSD
3516
RTRNW
3521
VLQQK
3526
IEGET
3531
KESNY
3536
AKLIE
3541
MNGGG
3546
TGCNH
3551
ELEMI
3556
RQKLQ
3561
CVASK
3566
LQVLP
3571
QKASE
3576
RLQFE
3581
TADDE
3586
DFIWV
3591
QENID
3596
EIILQ
3601
LQKLT
3606
GQQGE
3611
EPSLV
3616
SPSTS
3621
CGSLT
3626
ERLLR
3631
QNAEL
3636
TGHIS
3641
QLTEE
3646
KNDLR
3651
NMVMK
3656
LEEQI
3661
RWYRQ
3666
TGAGR
3671
DNSSR
3676
FSLNG
3681
GANIE
3686
AIIAS
3691
EKEVW
3696
NREKL
3701
TLQKS
3706
LKRAE
3711
AEVYK
3716
LKAEL
3721
RNDSL
3726
LQTLS
3731
PDSEH
3736
VTLKR
3741
IYGKY
3746
LRAES
3751
FRKAL
3756
IYQKK
3761
YLLLL
3766
LGGFQ
3771
ECEDA
3776
TLALL
3781
ARMGG
3786
QPAFT
3791
DLEVI
3796
TNRPK
3801
GFTRF
3806
RSAVR
3811
VSIAI
3816
SRMKF
3821
LVRRW
3826
HRVTG
3831
SVSIN
3836
INRDG
3841
FGLNQ
3846
GAEKT
3851
DSFYH
3856
SSGGL
3861
ELYGE
3866
PRHTT
3871
YRSRS
3876
DLDYI
3881
RSPLP
3886
FQNRY
3891
PGTPA
3896
DFNPG
3901
SLACS
3906
QLQNY
3911
DPDRA
3916
LTDYI
3921
TRLEA
3926
LQRRL
3931
GTIQS
3936
GALSL
3941
TTSWQ
3946
HHSAR
3951
PTAPL
3956
SLKFF
3961
HTH
3966
Mutation Information
DNA mutation:
c.T2432C
Peptide Range:
1174 ~ 1198
Mut AA position:
1186 (13 in Wild Type peptide)
Alignment
Wild Type:
"TQETGDEGKPLHLLIGKLQKAVSEE
||||||||||||.||||||||||||
Mutant:
TQETGDEGKPLHPLIGKLQKAVSEE"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

TQETGDEGKPLHPLIGKLQKAVSEE

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT